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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010211289> ?p ?o ?g. }

• W2010211289 abstract "We reported recently the Structure-Activity Relationship (SAR) of a class of CXCL8 allosteric modulators. They invariably share a 2-arylpropionic moiety so far considered a key structural determinant of the biological activity. We show the results of recent SAR studies on a novel series of phenylacetic derivatives supported by a combined approach of mutagenesis experiments and conformational analysis. The results suggest novel insights on the fine role of the propionic/acetic chain in the modulation of CXCL8 receptors." @default.
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• W2010211289 date "2009-08-01" @default.
• W2010211289 modified "2023-09-23" @default.
• W2010211289 title "Structure–Activity Relationship of novel phenylacetic CXCR1 inhibitors" @default.
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• W2010211289 doi "https://doi.org/10.1016/j.bmcl.2009.06.027" @default.
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