FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010221837> ?p ?o ?g. }

• W2010221837 endingPage "856" @default.
• W2010221837 startingPage "849" @default.
• W2010221837 abstract "Background. We have previously reported that by means of a breath test with intravenously administered L-[1-13C] phenylalanine (13Cphe), hepatopathy could be quantitatively evaluated by measuring expiratory 13CO2 levels in a short period. It is known that phenylalanine hydroxylase activity (PAHA) plays an important role in phenylalanine metabolism. We examined the relationship between changes in PAHA and the results of the 13Cphe breath test during hepatic regeneration in a rat model of 70% hepatectomy, to assess their usefulness for evaluating hepatic regeneration. Methods. Male Wistar rats (Shizvoka Laboratory Animal Center, Hamamatsu, Japan) weighing 230 to 290 g were subjected to 70% hepatectomy under anesthesia with sodium pentobarbital. One, 2, 3, 5, 7, and 14 days postoperatively, 30 mg/kg 13Cphe was intravenously injected into the femoral vein, and the increase in exhaled 13CO2 (Δ13CO2) was measured for 15 minutes. Simple laparotomy was performed in control rats. After the breath test, the regenerated liver was removed and weighed. The amount of DNA, amount of hepatic tissue total protein (TP), and PAHA were determined. Results. The r between liver weight/body weight and PAHA, between DNA and PAHA, and between TP and PAHA were 0.832, 0.720, and 0.758, respectively. Breath test graphs revealed that liver weight/body weight, DNA, and TP showed the best correlations with the peak value of Δ13CO2 (liver weight/body weight percentage, r = 0.801; DNA, r = 0.660; TP, r = 0.706), and r between PAHA and peak value was 0.638. Conclusions. These results suggest that measurement of PAHA in regenerated liver is an effective method for following up liver function after hepatic resection. Moreover, the 13Cphe breath test may also be useful to evaluate liver function after partial hepatectomy. Surgery 2002;132:849-56." @default.
• W2010221837 created "2016-06-24" @default.
• W2010221837 creator A5028206707 @default.
• W2010221837 creator A5040477628 @default.
• W2010221837 creator A5041567002 @default.
• W2010221837 creator A5059623734 @default.
• W2010221837 creator A5069502632 @default.
• W2010221837 creator A5081950928 @default.
• W2010221837 date "2002-11-01" @default.
• W2010221837 modified "2023-09-27" @default.
• W2010221837 title "Recovery of liver function in two-third partial hepatectomized rats evaluated by L-[1-13C]phenylalanine breath test" @default.
• W2010221837 cites W151282024 @default.
• W2010221837 cites W1524236485 @default.
• W2010221837 cites W1574726974 @default.
• W2010221837 cites W181242617 @default.
• W2010221837 cites W1971061718 @default.
• W2010221837 cites W1971911112 @default.
• W2010221837 cites W1975219904 @default.
• W2010221837 cites W1977476963 @default.
• W2010221837 cites W1986398072 @default.
• W2010221837 cites W1986798034 @default.
• W2010221837 cites W1989329516 @default.
• W2010221837 cites W1996986690 @default.
• W2010221837 cites W2003160173 @default.
• W2010221837 cites W2004305056 @default.
• W2010221837 cites W2024986726 @default.
• W2010221837 cites W2031504305 @default.
• W2010221837 cites W2040117573 @default.
• W2010221837 cites W2041278399 @default.
• W2010221837 cites W2058515064 @default.
• W2010221837 cites W2071580040 @default.
• W2010221837 cites W2075423334 @default.
• W2010221837 cites W2076271795 @default.
• W2010221837 cites W2078183000 @default.
• W2010221837 cites W2080154945 @default.
• W2010221837 cites W2088725852 @default.
• W2010221837 cites W2101325170 @default.
• W2010221837 cites W2138391231 @default.
• W2010221837 cites W2140528975 @default.
• W2010221837 cites W2152233239 @default.
• W2010221837 cites W2156698123 @default.
• W2010221837 cites W2160297030 @default.
• W2010221837 cites W2247149472 @default.
• W2010221837 cites W2261074722 @default.
• W2010221837 cites W2285466600 @default.
• W2010221837 cites W2413010272 @default.
• W2010221837 cites W28865656 @default.
• W2010221837 cites W78633279 @default.
• W2010221837 doi "https://doi.org/10.1067/msy.2002.127947" @default.
• W2010221837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12464870" @default.
• W2010221837 hasPublicationYear "2002" @default.
• W2010221837 type Work @default.
• W2010221837 sameAs 2010221837 @default.
• W2010221837 citedByCount "16" @default.
• W2010221837 countsByYear W20102218372012 @default.
• W2010221837 crossrefType "journal-article" @default.
• W2010221837 hasAuthorship W2010221837A5028206707 @default.
• W2010221837 hasAuthorship W2010221837A5040477628 @default.
• W2010221837 hasAuthorship W2010221837A5041567002 @default.
• W2010221837 hasAuthorship W2010221837A5059623734 @default.
• W2010221837 hasAuthorship W2010221837A5069502632 @default.
• W2010221837 hasAuthorship W2010221837A5081950928 @default.
• W2010221837 hasConcept C126322002 @default.
• W2010221837 hasConcept C134018914 @default.
• W2010221837 hasConcept C140793950 @default.
• W2010221837 hasConcept C141071460 @default.
• W2010221837 hasConcept C147583825 @default.
• W2010221837 hasConcept C159110652 @default.
• W2010221837 hasConcept C185592680 @default.
• W2010221837 hasConcept C2775981797 @default.
• W2010221837 hasConcept C2776409635 @default.
• W2010221837 hasConcept C2776909242 @default.
• W2010221837 hasConcept C2777431362 @default.
• W2010221837 hasConcept C515207424 @default.
• W2010221837 hasConcept C55493867 @default.
• W2010221837 hasConcept C71924100 @default.
• W2010221837 hasConcept C86803240 @default.
• W2010221837 hasConceptScore W2010221837C126322002 @default.
• W2010221837 hasConceptScore W2010221837C134018914 @default.
• W2010221837 hasConceptScore W2010221837C140793950 @default.
• W2010221837 hasConceptScore W2010221837C141071460 @default.
• W2010221837 hasConceptScore W2010221837C147583825 @default.
• W2010221837 hasConceptScore W2010221837C159110652 @default.
• W2010221837 hasConceptScore W2010221837C185592680 @default.
• W2010221837 hasConceptScore W2010221837C2775981797 @default.
• W2010221837 hasConceptScore W2010221837C2776409635 @default.
• W2010221837 hasConceptScore W2010221837C2776909242 @default.
• W2010221837 hasConceptScore W2010221837C2777431362 @default.
• W2010221837 hasConceptScore W2010221837C515207424 @default.
• W2010221837 hasConceptScore W2010221837C55493867 @default.
• W2010221837 hasConceptScore W2010221837C71924100 @default.
• W2010221837 hasConceptScore W2010221837C86803240 @default.
• W2010221837 hasIssue "5" @default.
• W2010221837 hasLocation W20102218371 @default.
• W2010221837 hasLocation W20102218372 @default.
• W2010221837 hasOpenAccess W2010221837 @default.
• W2010221837 hasPrimaryLocation W20102218371 @default.
• W2010221837 hasRelatedWork W1992523552 @default.

• next