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- W2010224713 abstract "Intrinsic oscillations at the level of the membrane potential are a widespread feature of nerve cells. Several evidences exist that, in particular, sensory neurons combine their oscillatory membrane potentials with intrinsic, membrane and/or synaptic noise to obtain sensitive encoding properties. An interesting example are mammalian cold receptors where stimulus transduction results from modulation of intrinsic receptor oscillations with essential contribution of noise thereby generating a rich spectrum of impulse patterns. To further explore the dynamics of these receptors we here investigate an HH-type model for oscillations and spike initiation in cold receptors. By use of a biophysically plausible temperature scaling and with addition of noise, the model successfully mimicks the principle temperature-dependence of stationary impulse patterns of real cold receptors. Our results suggest that interactions between stochastic and deterministic dynamics are of functional importance for the encoding charcteristics of cold receptors." @default.
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- W2010224713 date "2000-09-01" @default.
- W2010224713 modified "2023-10-03" @default.
- W2010224713 title "Stochastic encoding in sensory neurons: impulse patterns of mammalian cold receptors" @default.
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- W2010224713 doi "https://doi.org/10.1016/s0960-0779(99)00126-5" @default.
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