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- W2010229146 abstract "ABSTRACT To evaluate the usefulness of tissue fluorescence to distinguish normal from atherosclerotic regions inhuman arteries, we examined fluorescence spectral maps obtained over a wide range of excitation andemission wavelengths from 15 normal and 26 atherosclerotic human aorta specimens. After defining criteriato maximize safety, ease of use, reproducibility and predictive accuracy, we derived an optimum fluorescencediscriminant function from this data set which reliably identifies normal and diseased arterial tissue, is independent of sampling device characteristics and vessel geometry, and utilizes simple, available methodologies. This discriminant function, the ratio of fluorescence intensity emitted at 380 nm to thatemitted at 420 nm with excitation wavelength of 360 nm [(I380420)360] compared favorably to otherfluorescent discrimination techniques previously described.1. INTRODUCTIONInitial attempts at human coronary artery laser angioplasty uggest that controlled application of laserenergy will be necessary for safe and effective recanalization'2. Such studies have heightened interest in" @default.
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- W2010229146 date "1989-06-15" @default.
- W2010229146 modified "2023-09-23" @default.
- W2010229146 title "Fluorescence Spectra Of Normal And Atherosclerotic Human Aorta: Optimum Discriminant Analysis" @default.
- W2010229146 doi "https://doi.org/10.1117/12.952109" @default.
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