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- W2010278537 abstract "Recovery from gram-negative septicemia depends on the successful joint action of antibiotics and host defense mechanisms. The possible enhancement of host defense with either immunotherapy or antibiotic treatment has been the subject of numerous investigations. Because of the great similarity of core epitopes within different species of Enterobacteriaceae, most studies have focused on the development of cross-reactive and/or cross-protective antibodies to these common epitopes. The majority of strains that cause severe gram-negative septicemia, however, possess a complete 0 antigen (and often a K antigen) that maycamouflage the common antigenic determinants. Antibodies to these common antigens therefore may be unable to recognize their targets. Subinhibitory concentrations of certain antibiotics have been shown to alter surface structures of Enterobacteriaceae to such an extent that the structures no longer camouflage underlying epitopes, allowing binding of cross-reactive or cross-protective antibodies to these epitopes. Thus antibiotics and antibodies may synergistically fight infection." @default.
- W2010278537 created "2016-06-24" @default.
- W2010278537 creator A5031344953 @default.
- W2010278537 creator A5065619937 @default.
- W2010278537 date "1991-07-01" @default.
- W2010278537 modified "2023-09-24" @default.
- W2010278537 title "Role of Antibodies and Antibiotics in Aerobic Gram-Negative Septicemia: Possible Synergism Between Antimicrobial Treatment and Immunotherapy" @default.
- W2010278537 cites W107477466 @default.
- W2010278537 cites W123342169 @default.
- W2010278537 cites W1458582449 @default.
- W2010278537 cites W1522899169 @default.
- W2010278537 cites W1530423872 @default.
- W2010278537 cites W1531521794 @default.
- W2010278537 cites W1537098436 @default.
- W2010278537 cites W1547064788 @default.
- W2010278537 cites W1556511762 @default.
- W2010278537 cites W1568275547 @default.
- W2010278537 cites W1604363183 @default.
- W2010278537 cites W1619510002 @default.
- W2010278537 cites W1707385839 @default.
- W2010278537 cites W1758217761 @default.
- W2010278537 cites W1819898082 @default.
- W2010278537 cites W1833207062 @default.
- W2010278537 cites W1836782776 @default.
- W2010278537 cites W1838733824 @default.
- W2010278537 cites W1845158209 @default.
- W2010278537 cites W1852463882 @default.
- W2010278537 cites W1854128845 @default.
- W2010278537 cites W1887233856 @default.
- W2010278537 cites W1897200274 @default.
- W2010278537 cites W1899176882 @default.
- W2010278537 cites W1921242279 @default.
- W2010278537 cites W1941873691 @default.
- W2010278537 cites W1952804450 @default.
- W2010278537 cites W1961243873 @default.
- W2010278537 cites W1961875834 @default.
- W2010278537 cites W1965323794 @default.
- W2010278537 cites W1966450495 @default.
- W2010278537 cites W1969331579 @default.
- W2010278537 cites W1969358382 @default.
- W2010278537 cites W1971264244 @default.
- W2010278537 cites W1971372846 @default.
- W2010278537 cites W1973652464 @default.
- W2010278537 cites W1978501963 @default.
- W2010278537 cites W1981878606 @default.
- W2010278537 cites W1986147894 @default.
- W2010278537 cites W1988719268 @default.
- W2010278537 cites W1989557398 @default.
- W2010278537 cites W1990407734 @default.
- W2010278537 cites W1992258769 @default.
- W2010278537 cites W1992737694 @default.
- W2010278537 cites W1996341536 @default.
- W2010278537 cites W1999262804 @default.
- W2010278537 cites W1999713685 @default.
- W2010278537 cites W2000559951 @default.
- W2010278537 cites W2002508503 @default.
- W2010278537 cites W2007164880 @default.
- W2010278537 cites W2007738702 @default.
- W2010278537 cites W2008742324 @default.
- W2010278537 cites W2009727962 @default.
- W2010278537 cites W2014338973 @default.
- W2010278537 cites W2014781329 @default.
- W2010278537 cites W2018261520 @default.
- W2010278537 cites W2020906214 @default.
- W2010278537 cites W2021327461 @default.
- W2010278537 cites W2023122744 @default.
- W2010278537 cites W2024096824 @default.
- W2010278537 cites W2025107120 @default.
- W2010278537 cites W2029600545 @default.
- W2010278537 cites W2030998727 @default.
- W2010278537 cites W2033981815 @default.
- W2010278537 cites W2038998020 @default.
- W2010278537 cites W2039292786 @default.
- W2010278537 cites W2048009202 @default.
- W2010278537 cites W2049332147 @default.
- W2010278537 cites W2053352564 @default.
- W2010278537 cites W2054524213 @default.
- W2010278537 cites W2055496485 @default.
- W2010278537 cites W2056729760 @default.
- W2010278537 cites W2063529632 @default.
- W2010278537 cites W2063680032 @default.
- W2010278537 cites W2064107559 @default.
- W2010278537 cites W2066197563 @default.
- W2010278537 cites W2068546132 @default.
- W2010278537 cites W2068964705 @default.
- W2010278537 cites W2071163319 @default.
- W2010278537 cites W2071833467 @default.
- W2010278537 cites W2073337046 @default.
- W2010278537 cites W2077699049 @default.
- W2010278537 cites W2078642823 @default.
- W2010278537 cites W2081430713 @default.
- W2010278537 cites W2081860876 @default.
- W2010278537 cites W2083197320 @default.
- W2010278537 cites W2089621550 @default.
- W2010278537 cites W2090462235 @default.
- W2010278537 cites W2091479800 @default.
- W2010278537 cites W2093826422 @default.
- W2010278537 cites W2097330926 @default.