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• W2010283908 abstract "Summary Objective To evaluate the associations between triglyceride to high‐density lipoprotein cholesterol ( TG / HDL ‐C) ratios and the risks of gestational diabetes mellitus ( GDM ) and delivering large‐for‐gestational‐age ( LGA ) infant. Design This was a single‐centre prospective observational study. Patients Six hundred and thirty‐six women with a singleton pregnancy were recruited. Measurements Lipids profile, HbA1c and glucose were measured at the time of oral glucose tolerance test ( OGTT ) during 24–28 gestational weeks. TG / HDL ‐C ratios were calculated and clinical data including perinatal parameters were analysed. Results The prevalence of GDM was 17·30% ( n = 110) and LGA was 3·93% ( n = 25) in this study. TG / HDL ‐C ratios were found to be significantly higher in GDM group ( P < 0·01) and LGA group ( P = 0·045) compared with those in non‐ GDM group and non‐ LGA group, respectively. TG / HDL ‐C ratios were independently associated with the risks of GDM ( OR = 1·64, P = 0·02) and LGA ( OR = 2·87, P < 0·01). The area under the combined ROC curve of TG / HDL ‐C ratio and HbA1c to detect GDM was 0·705 (95% CI , 0·637–0·772). Furthermore, the area under the ROC curve of TG / HDL ‐C ratio combined with HbA1c and prepregnancy BMI to detect LGA was 0·806 (95% CI , 0·719–0·893). Conclusions TG / HDL ‐C ratios in combination with HbA1c and prepregnancy BMI can be good markers to predict the risks of GDM and delivering LGA infant." @default.
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• W2010283908 date "2015-03-06" @default.
• W2010283908 modified "2023-10-10" @default.
• W2010283908 title "The associations between triglyceride to high‐density lipoprotein cholesterol ratios and the risks of gestational diabetes mellitus and large‐for‐gestational‐age infant" @default.
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• W2010283908 doi "https://doi.org/10.1111/cen.12742" @default.
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