Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010284891> ?p ?o ?g. }
- W2010284891 endingPage "375" @default.
- W2010284891 startingPage "365" @default.
- W2010284891 abstract "The transcriptional activator, VnfA, is necessary for the expression of the structural genes encoding vanadium-dependent nitrogenase in Azotobacter vinelandii. We have previously reported that VnfA harbours a Fe-S cluster as a prosthetic group, presumably a 3Fe-4S type, which is vital for the transcriptionally active VnfA. A plausible effector molecule is a reactive oxygen species (ROS), which disassembles the Fe-S cluster switching the active VnfA to become fully inactive. This finding prompted us to investigate the effect of nitric oxide (NO), another physiologically important radical species on the VnfA activity. Unlike ROS, the VnfA activity was moderately inhibited and converged to 70% of the maximum by NO irrespective of its concentration. The Fe-S cluster of VnfA was found to react with NO to form a dinitrosyl–iron complex, either in the dimeric or monomeric form, dependent on the relative stoichiometry of NO to the Fe-S cluster. The VnfA species harbouring the dinitrosyl–iron complexes in each form exhibited 50% ATPase activity compared to the active VnfA. The findings of this study would open an argument about a biological effect of NO on nitrogenase in light of its transcriptional regulatory system." @default.
- W2010284891 created "2016-06-24" @default.
- W2010284891 creator A5006279424 @default.
- W2010284891 creator A5017240422 @default.
- W2010284891 creator A5048002266 @default.
- W2010284891 creator A5062077739 @default.
- W2010284891 creator A5066307283 @default.
- W2010284891 date "2014-12-09" @default.
- W2010284891 modified "2023-09-27" @default.
- W2010284891 title "Effect of nitric oxide on VnfA, a transcriptional activator of VFe-nitrogenase in Azotobacter vinelandii" @default.
- W2010284891 cites W1513371424 @default.
- W2010284891 cites W1563367929 @default.
- W2010284891 cites W1630518968 @default.
- W2010284891 cites W1665129578 @default.
- W2010284891 cites W1900428721 @default.
- W2010284891 cites W1931589825 @default.
- W2010284891 cites W1966517868 @default.
- W2010284891 cites W1969826059 @default.
- W2010284891 cites W1969965615 @default.
- W2010284891 cites W1973328394 @default.
- W2010284891 cites W1973995249 @default.
- W2010284891 cites W1975266973 @default.
- W2010284891 cites W2003089170 @default.
- W2010284891 cites W2004083823 @default.
- W2010284891 cites W2017719449 @default.
- W2010284891 cites W2021091767 @default.
- W2010284891 cites W2026034783 @default.
- W2010284891 cites W2041859669 @default.
- W2010284891 cites W2042843861 @default.
- W2010284891 cites W2044280081 @default.
- W2010284891 cites W2049595568 @default.
- W2010284891 cites W2051317564 @default.
- W2010284891 cites W2055567280 @default.
- W2010284891 cites W2056519327 @default.
- W2010284891 cites W2060740333 @default.
- W2010284891 cites W2062193292 @default.
- W2010284891 cites W2065237831 @default.
- W2010284891 cites W2066794906 @default.
- W2010284891 cites W2067215036 @default.
- W2010284891 cites W2081338348 @default.
- W2010284891 cites W2087611734 @default.
- W2010284891 cites W2092682318 @default.
- W2010284891 cites W2095417019 @default.
- W2010284891 cites W2096413679 @default.
- W2010284891 cites W2099301511 @default.
- W2010284891 cites W2112242238 @default.
- W2010284891 cites W2113990685 @default.
- W2010284891 cites W2115845817 @default.
- W2010284891 cites W2124345503 @default.
- W2010284891 cites W2126626255 @default.
- W2010284891 cites W2144296814 @default.
- W2010284891 cites W2145166380 @default.
- W2010284891 cites W2154274648 @default.
- W2010284891 cites W2162387553 @default.
- W2010284891 cites W2166005059 @default.
- W2010284891 cites W43357869 @default.
- W2010284891 doi "https://doi.org/10.1093/jb/mvu083" @default.
- W2010284891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25500211" @default.
- W2010284891 hasPublicationYear "2014" @default.
- W2010284891 type Work @default.
- W2010284891 sameAs 2010284891 @default.
- W2010284891 citedByCount "1" @default.
- W2010284891 countsByYear W20102848912020 @default.
- W2010284891 crossrefType "journal-article" @default.
- W2010284891 hasAuthorship W2010284891A5006279424 @default.
- W2010284891 hasAuthorship W2010284891A5017240422 @default.
- W2010284891 hasAuthorship W2010284891A5048002266 @default.
- W2010284891 hasAuthorship W2010284891A5062077739 @default.
- W2010284891 hasAuthorship W2010284891A5066307283 @default.
- W2010284891 hasConcept C104317684 @default.
- W2010284891 hasConcept C12554922 @default.
- W2010284891 hasConcept C141280058 @default.
- W2010284891 hasConcept C178790620 @default.
- W2010284891 hasConcept C181199279 @default.
- W2010284891 hasConcept C181440489 @default.
- W2010284891 hasConcept C185592680 @default.
- W2010284891 hasConcept C2776159390 @default.
- W2010284891 hasConcept C2776217839 @default.
- W2010284891 hasConcept C36857842 @default.
- W2010284891 hasConcept C48349386 @default.
- W2010284891 hasConcept C51785407 @default.
- W2010284891 hasConcept C519581460 @default.
- W2010284891 hasConcept C537208039 @default.
- W2010284891 hasConcept C55493867 @default.
- W2010284891 hasConcept C86803240 @default.
- W2010284891 hasConcept C88045685 @default.
- W2010284891 hasConceptScore W2010284891C104317684 @default.
- W2010284891 hasConceptScore W2010284891C12554922 @default.
- W2010284891 hasConceptScore W2010284891C141280058 @default.
- W2010284891 hasConceptScore W2010284891C178790620 @default.
- W2010284891 hasConceptScore W2010284891C181199279 @default.
- W2010284891 hasConceptScore W2010284891C181440489 @default.
- W2010284891 hasConceptScore W2010284891C185592680 @default.
- W2010284891 hasConceptScore W2010284891C2776159390 @default.
- W2010284891 hasConceptScore W2010284891C2776217839 @default.
- W2010284891 hasConceptScore W2010284891C36857842 @default.
- W2010284891 hasConceptScore W2010284891C48349386 @default.
- W2010284891 hasConceptScore W2010284891C51785407 @default.