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- W2010286570 abstract "1472 We examined the hypothesis that glucose flux was directly related to relative exercise intensity both before and after a 12 week cycle ergometer training program (5 d/w, 1 hr, 75% VO2peak) in healthy female subjects(n=17; age=23.8±2.0 years). Two pre-training trials (45% and 65% of VO2peak) and two post-training trials (same absolute workload-65% of old VO2peak) and same relative-65% of new VO2peak) were performed on 9 subjects using a primed-continuous infusion of [1-13C]- and [6,6-2H]glucose. Eight additional trials were conducted using[6,6-2H]glucose, alone. Subjects were studied post-absorptive for 90 min of rest and 1 hour of cycling exercise. After training, subjects increased VO2peak by 25.2±2.4%. Pre-training, the intensity effect on glucose kinetics was evident between 45% and 65% of VO2peak with rate of appearance (Ra: 4.52±0.25 vs. 5.53±0.33 mg·kg-1·min-1), disappearance (Rd: 4.46±0.25 vs. 5.54±0.33 mg·kg-1·min-1), oxidation (Rox: 2.45±0.16 vs. 4.35±0.26 mg·kg-1·min-1) and metabolic clearance (MCR: 5.44±0.37 vs. 6.67±0.44 ml·kg-1·min-1) of glucose being significantly greater (p≤0.05) in the 65% than the 45% trial. Training reduced Ra to(4.70±0.30), Rd (4.69±0.20), MCR (5.41±0.29), and Rox(3.54±0.50), when tested at the same absolute workload (p≤0.05). However, when subjects were tested at the same relative workload, Ra, Rd, MCR, and Rox were not significantly different following training. These results show that in young women: 1) glucose use is directly related to exercise intensity, 2) training decreases glucose flux for a given power output, and 3) when expressed as relative exercise intensity, training does not affect the magnitude of blood glucose flux and oxidation during exercise." @default.
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- W2010286570 title "GLUCOSE FLUX IN YOUNG WOMEN DURING EXERCISE BEFORE AND AFTER ENDURANCE TRAINING" @default.
- W2010286570 doi "https://doi.org/10.1097/00005768-199805001-01471" @default.
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