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- W2010314567 abstract "Objective Chronic infections and liver diseases may lead to malnutrition. However, growth failure is rarely reported in chronic hepatitis B. We aimed to establish the nutritional status of children with chronic hepatitis B and the relation between anthropometric data and laboratory findings in a population with low socioeconomic status. Methods Anthropometrical and laboratory findings were noted from the hospital records. Cases with and without malnutrition were compared with regard to sex, age, histological activity (HAI) scores, aspartate aminotransferase, alanine aminotransferase, γ-glutamyl transpeptidase, protein, albumin, and hepatitis B virus (HBV) DNA levels. Results Eighty children, of which 36 (45%) were girls, with a mean age of 11.5±3.2 years were enrolled in the study. Malnutrition was found in 39 (49%). Acute malnutrition (24 out of 39, 61.5%) was the most common form. There was no difference of age or sex between children with and without malnutrition. Age of diagnosis was higher and duration of follow-up was shorter in cases with malnutrition (P = 0.051 and P = 0.016, respectively). In children with malnutrition, aspartate aminotransferase levels were significantly higher but other laboratory results were not different. Malnutrition rate was not different between groups that did and did not receive treatment or that did and did not respond to treatment. Anthropometrical data and malnutrition rate was similar in children with high and low HAI scores. Conclusion As features suggesting severe liver disease like high alanine aminotransferase values, HAI scores, or HBV DNA levels were not different in children with and without malnutrition, it may be proposed that chronic HBV infection does not have an effect on nutritional status." @default.
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- W2010314567 date "2009-11-01" @default.
- W2010314567 modified "2023-09-25" @default.
- W2010314567 title "Nutritional status of children with chronic hepatitis B in a population with low socioeconomic status" @default.
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- W2010314567 doi "https://doi.org/10.1097/meg.0b013e32832a4ec3" @default.
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