Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010329700> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2010329700 abstract "Equatorial and axial N-methyl diastereomers of the analgesic drug nefopam hydrochloride were differentiated using a hypothetical model of the serotonin (5-hydroxytryptamine) uptake area. Both diastereomers were placed within the hypothetical model area to form van der Waals interactions involving the phenyl group of nefopam, but only in the case of the equatorial N-methyl epimer was the +N--H bond able to be oriented towards the proposed hydrogen-bonding site. A comparison of equatorial N-methyl nefopam hydrochloride enantiomers in the proposed two-site binding mode points to less severe nonbonding steric interactions for the (+)-(1S,5S)-enantiomer compared with the (-)-(1R,5R)-isomer." @default.
- W2010329700 created "2016-06-24" @default.
- W2010329700 creator A5053438967 @default.
- W2010329700 creator A5061290907 @default.
- W2010329700 date "1989-02-01" @default.
- W2010329700 modified "2023-09-24" @default.
- W2010329700 title "Stereoisomer Differentiation for the Analgesic Drug Nefopam Hydrochloride Using Modeling Studies of Serotonin Uptake Area" @default.
- W2010329700 cites W12773230 @default.
- W2010329700 cites W1977294562 @default.
- W2010329700 cites W1987137765 @default.
- W2010329700 cites W1993863683 @default.
- W2010329700 cites W2004496093 @default.
- W2010329700 cites W2005381654 @default.
- W2010329700 cites W2023858005 @default.
- W2010329700 cites W2024371859 @default.
- W2010329700 cites W2027728223 @default.
- W2010329700 cites W2036610598 @default.
- W2010329700 cites W2045502014 @default.
- W2010329700 cites W2049957442 @default.
- W2010329700 cites W2050622977 @default.
- W2010329700 cites W2063658060 @default.
- W2010329700 cites W2064588775 @default.
- W2010329700 cites W2089112003 @default.
- W2010329700 cites W2092468144 @default.
- W2010329700 cites W2092839111 @default.
- W2010329700 cites W2094261239 @default.
- W2010329700 cites W2112774062 @default.
- W2010329700 cites W2135694192 @default.
- W2010329700 cites W2171507306 @default.
- W2010329700 cites W3004969213 @default.
- W2010329700 doi "https://doi.org/10.1002/jps.2600780202" @default.
- W2010329700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2715942" @default.
- W2010329700 hasPublicationYear "1989" @default.
- W2010329700 type Work @default.
- W2010329700 sameAs 2010329700 @default.
- W2010329700 citedByCount "11" @default.
- W2010329700 crossrefType "journal-article" @default.
- W2010329700 hasAuthorship W2010329700A5053438967 @default.
- W2010329700 hasAuthorship W2010329700A5061290907 @default.
- W2010329700 hasConcept C112887158 @default.
- W2010329700 hasConcept C138716334 @default.
- W2010329700 hasConcept C170493617 @default.
- W2010329700 hasConcept C178790620 @default.
- W2010329700 hasConcept C185592680 @default.
- W2010329700 hasConcept C201194858 @default.
- W2010329700 hasConcept C203130289 @default.
- W2010329700 hasConcept C2775864247 @default.
- W2010329700 hasConcept C2776460385 @default.
- W2010329700 hasConcept C2780820201 @default.
- W2010329700 hasConcept C32909587 @default.
- W2010329700 hasConcept C486523 @default.
- W2010329700 hasConcept C55493867 @default.
- W2010329700 hasConcept C71240020 @default.
- W2010329700 hasConcept C71924100 @default.
- W2010329700 hasConcept C98274493 @default.
- W2010329700 hasConceptScore W2010329700C112887158 @default.
- W2010329700 hasConceptScore W2010329700C138716334 @default.
- W2010329700 hasConceptScore W2010329700C170493617 @default.
- W2010329700 hasConceptScore W2010329700C178790620 @default.
- W2010329700 hasConceptScore W2010329700C185592680 @default.
- W2010329700 hasConceptScore W2010329700C201194858 @default.
- W2010329700 hasConceptScore W2010329700C203130289 @default.
- W2010329700 hasConceptScore W2010329700C2775864247 @default.
- W2010329700 hasConceptScore W2010329700C2776460385 @default.
- W2010329700 hasConceptScore W2010329700C2780820201 @default.
- W2010329700 hasConceptScore W2010329700C32909587 @default.
- W2010329700 hasConceptScore W2010329700C486523 @default.
- W2010329700 hasConceptScore W2010329700C55493867 @default.
- W2010329700 hasConceptScore W2010329700C71240020 @default.
- W2010329700 hasConceptScore W2010329700C71924100 @default.
- W2010329700 hasConceptScore W2010329700C98274493 @default.
- W2010329700 hasLocation W20103297001 @default.
- W2010329700 hasLocation W20103297002 @default.
- W2010329700 hasOpenAccess W2010329700 @default.
- W2010329700 hasPrimaryLocation W20103297001 @default.
- W2010329700 hasRelatedWork W1970204526 @default.
- W2010329700 hasRelatedWork W1976173055 @default.
- W2010329700 hasRelatedWork W1977212555 @default.
- W2010329700 hasRelatedWork W2010329700 @default.
- W2010329700 hasRelatedWork W2015543498 @default.
- W2010329700 hasRelatedWork W2062897035 @default.
- W2010329700 hasRelatedWork W2949193459 @default.
- W2010329700 hasRelatedWork W2951448726 @default.
- W2010329700 hasRelatedWork W2956376780 @default.
- W2010329700 hasRelatedWork W3036100935 @default.
- W2010329700 isParatext "false" @default.
- W2010329700 isRetracted "false" @default.
- W2010329700 magId "2010329700" @default.
- W2010329700 workType "article" @default.