Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010349723> ?p ?o ?g. }
- W2010349723 endingPage "103" @default.
- W2010349723 startingPage "93" @default.
- W2010349723 abstract "We sought to determine whether the changes in microvascular endothelial cells (EC) caused by a polarized chronic inflammatory stimulus depend on proximity to the stimulus. C3H mice were infected with Mycoplasma pulmonis, which attaches to the airway epithelium and creates a polarized inflammatory stimulus across the airway wall. At 1, 2, or 4 weeks, the tracheal vasculature was stained by perfusion of silver nitrate to mark EC borders or biotinylated Lycopersicon esculentum lectin to label the EC surface and adherent leukocytes. E-selectin immunoreactivity and EC proliferation were also localized. We found that the size, shape, and immunoreactivity for adhesion molecules on EC nearest the airway lumen (subepithelial EC) were different from those on the opposite surface of the same vessels. Subepithelial EC were smaller, more irregular in shape, had greater E-selectin immunoreactivity, and had twice as many adherent leukocytes. In contrast, proliferating EC were uniformly distributed around the vessel circumference. We conclude that the polarized stimulus created by M. pulmonis infection differentially changes the size, shape, and function of EC nearest the airway epithelium. This heterogeneity may result from a gradient of inflammatory mediators that triggers the influx of leukocytes into the airway lumen." @default.
- W2010349723 created "2016-06-24" @default.
- W2010349723 creator A5003462092 @default.
- W2010349723 creator A5015053419 @default.
- W2010349723 creator A5029984044 @default.
- W2010349723 creator A5030977027 @default.
- W2010349723 date "1999-07-01" @default.
- W2010349723 modified "2023-10-17" @default.
- W2010349723 title "Endothelial Cell Heterogeneity in Venules of Mouse Airways Induced by Polarized Inflammatory Stimulus" @default.
- W2010349723 cites W1820527381 @default.
- W2010349723 cites W1830344560 @default.
- W2010349723 cites W184065906 @default.
- W2010349723 cites W1902747848 @default.
- W2010349723 cites W1968968207 @default.
- W2010349723 cites W1982918107 @default.
- W2010349723 cites W1993050941 @default.
- W2010349723 cites W1997165412 @default.
- W2010349723 cites W2015531285 @default.
- W2010349723 cites W2023762992 @default.
- W2010349723 cites W2025409425 @default.
- W2010349723 cites W2025745642 @default.
- W2010349723 cites W2048185125 @default.
- W2010349723 cites W2076399226 @default.
- W2010349723 cites W2077098817 @default.
- W2010349723 cites W2080436034 @default.
- W2010349723 cites W2082964997 @default.
- W2010349723 cites W2084874619 @default.
- W2010349723 cites W2092027489 @default.
- W2010349723 cites W2092186152 @default.
- W2010349723 cites W2103633130 @default.
- W2010349723 cites W2110913661 @default.
- W2010349723 cites W2139660331 @default.
- W2010349723 cites W2155783433 @default.
- W2010349723 cites W2182151941 @default.
- W2010349723 cites W2203045174 @default.
- W2010349723 cites W2405177011 @default.
- W2010349723 cites W2418496815 @default.
- W2010349723 cites W34737126 @default.
- W2010349723 cites W2028553018 @default.
- W2010349723 doi "https://doi.org/10.1016/s0002-9440(10)65104-8" @default.
- W2010349723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1866655" @default.
- W2010349723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10393842" @default.
- W2010349723 hasPublicationYear "1999" @default.
- W2010349723 type Work @default.
- W2010349723 sameAs 2010349723 @default.
- W2010349723 citedByCount "30" @default.
- W2010349723 countsByYear W20103497232014 @default.
- W2010349723 countsByYear W20103497232016 @default.
- W2010349723 countsByYear W20103497232018 @default.
- W2010349723 countsByYear W20103497232020 @default.
- W2010349723 crossrefType "journal-article" @default.
- W2010349723 hasAuthorship W2010349723A5003462092 @default.
- W2010349723 hasAuthorship W2010349723A5015053419 @default.
- W2010349723 hasAuthorship W2010349723A5029984044 @default.
- W2010349723 hasAuthorship W2010349723A5030977027 @default.
- W2010349723 hasBestOaLocation W20103497232 @default.
- W2010349723 hasConcept C105702510 @default.
- W2010349723 hasConcept C105922876 @default.
- W2010349723 hasConcept C134018914 @default.
- W2010349723 hasConcept C141071460 @default.
- W2010349723 hasConcept C142724271 @default.
- W2010349723 hasConcept C15744967 @default.
- W2010349723 hasConcept C203014093 @default.
- W2010349723 hasConcept C2776992346 @default.
- W2010349723 hasConcept C2779918689 @default.
- W2010349723 hasConcept C2780098789 @default.
- W2010349723 hasConcept C529295009 @default.
- W2010349723 hasConcept C542102704 @default.
- W2010349723 hasConcept C71924100 @default.
- W2010349723 hasConcept C86803240 @default.
- W2010349723 hasConcept C87568996 @default.
- W2010349723 hasConcept C95444343 @default.
- W2010349723 hasConceptScore W2010349723C105702510 @default.
- W2010349723 hasConceptScore W2010349723C105922876 @default.
- W2010349723 hasConceptScore W2010349723C134018914 @default.
- W2010349723 hasConceptScore W2010349723C141071460 @default.
- W2010349723 hasConceptScore W2010349723C142724271 @default.
- W2010349723 hasConceptScore W2010349723C15744967 @default.
- W2010349723 hasConceptScore W2010349723C203014093 @default.
- W2010349723 hasConceptScore W2010349723C2776992346 @default.
- W2010349723 hasConceptScore W2010349723C2779918689 @default.
- W2010349723 hasConceptScore W2010349723C2780098789 @default.
- W2010349723 hasConceptScore W2010349723C529295009 @default.
- W2010349723 hasConceptScore W2010349723C542102704 @default.
- W2010349723 hasConceptScore W2010349723C71924100 @default.
- W2010349723 hasConceptScore W2010349723C86803240 @default.
- W2010349723 hasConceptScore W2010349723C87568996 @default.
- W2010349723 hasConceptScore W2010349723C95444343 @default.
- W2010349723 hasFunder F4320332161 @default.
- W2010349723 hasIssue "1" @default.
- W2010349723 hasLocation W20103497231 @default.
- W2010349723 hasLocation W20103497232 @default.
- W2010349723 hasLocation W20103497233 @default.
- W2010349723 hasLocation W20103497234 @default.
- W2010349723 hasOpenAccess W2010349723 @default.
- W2010349723 hasPrimaryLocation W20103497231 @default.
- W2010349723 hasRelatedWork W1997814296 @default.
- W2010349723 hasRelatedWork W2000434989 @default.