FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010359871> ?p ?o ?g. }

• W2010359871 endingPage "129" @default.
• W2010359871 startingPage "121" @default.
• W2010359871 abstract "Summary The bovine major histocompatibility complex ( MHC ) or BoLA is organized differently from typical mammalian MHC s in that a large portion of the class II region, called class IIb , has been transposed to a position near the centromere on bovine chromosome 23. Gene mapping indicated that the rearrangement resulted from a single inversion, but the boundaries and gene content of the inverted segment have not been fully determined. Here, we report the genomic sequence of BoLA IIb . Comparative sequence analysis with the human MHC revealed that the proximal inversion breakpoint occurred approximately 2.5 kb from the 3′ end of the glutamate‐cysteine ligase, catalytic subunit ( GCLC ) locus and that the distal breakpoint occurred about 2 kb from the 5′ end from a divergent class II DR β ‐like sequence designated DSB . Gene content, order and orientation of BoLA IIb are consistent with the single inversion hypothesis when compared with the corresponding region of the human class II MHC ( HLA class II ). Differences with HLA include the presence of a single histone H2B gene located between the proteasome subunit, beta type, 9 ( PSMB9 ) and DMB loci and a duplicated TAP2 with a variant splice site. BoLA IIb spans approximately 450 kb DNA, with 20 apparently intact genes and no obvious pseudogenes. The region contains 227 simple sequence repeats (SSRs) and approximately 167 kb of retroviral‐related repetitive DNA. Nineteen of the 20 genes identified in silico are supported by bovine EST data indicating that the functional gene content of BoLA IIb has not been diminished because it has been transposed from the remainder of BoLA genes." @default.
• W2010359871 created "2016-06-24" @default.
• W2010359871 creator A5003025455 @default.
• W2010359871 creator A5003945271 @default.
• W2010359871 creator A5021753814 @default.
• W2010359871 creator A5022844690 @default.
• W2010359871 creator A5025910539 @default.
• W2010359871 creator A5036093168 @default.
• W2010359871 creator A5051111376 @default.
• W2010359871 creator A5052546138 @default.
• W2010359871 creator A5056043869 @default.
• W2010359871 creator A5059626751 @default.
• W2010359871 date "2005-12-21" @default.
• W2010359871 modified "2023-10-16" @default.
• W2010359871 title "Comparative analysis of the bovine <i>MHC class IIb</i> sequence¹ identifies inversion breakpoints and three unexpected genes" @default.
• W2010359871 cites W1480645851 @default.
• W2010359871 cites W1497954397 @default.
• W2010359871 cites W1712008638 @default.
• W2010359871 cites W1979197138 @default.
• W2010359871 cites W1994896486 @default.
• W2010359871 cites W1999169677 @default.
• W2010359871 cites W2003994689 @default.
• W2010359871 cites W2005198251 @default.
• W2010359871 cites W2009992605 @default.
• W2010359871 cites W2012177908 @default.
• W2010359871 cites W2013974249 @default.
• W2010359871 cites W2029484053 @default.
• W2010359871 cites W2030665572 @default.
• W2010359871 cites W2032599295 @default.
• W2010359871 cites W2036721340 @default.
• W2010359871 cites W2040132703 @default.
• W2010359871 cites W2045253355 @default.
• W2010359871 cites W2045682866 @default.
• W2010359871 cites W2055043387 @default.
• W2010359871 cites W2062156010 @default.
• W2010359871 cites W2068873280 @default.
• W2010359871 cites W2081303646 @default.
• W2010359871 cites W2086579330 @default.
• W2010359871 cites W2106635753 @default.
• W2010359871 cites W2116244785 @default.
• W2010359871 cites W2119088963 @default.
• W2010359871 cites W2119923823 @default.
• W2010359871 cites W2121016876 @default.
• W2010359871 cites W2123181416 @default.
• W2010359871 cites W2134374259 @default.
• W2010359871 cites W2141847640 @default.
• W2010359871 cites W2143249496 @default.
• W2010359871 cites W2144362290 @default.
• W2010359871 cites W2145893715 @default.
• W2010359871 cites W2151119733 @default.
• W2010359871 cites W2166861783 @default.
• W2010359871 doi "https://doi.org/10.1111/j.1365-2052.2005.01395.x" @default.
• W2010359871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16573526" @default.
• W2010359871 hasPublicationYear "2005" @default.
• W2010359871 type Work @default.
• W2010359871 sameAs 2010359871 @default.
• W2010359871 citedByCount "33" @default.
• W2010359871 countsByYear W20103598712012 @default.
• W2010359871 countsByYear W20103598712013 @default.
• W2010359871 countsByYear W20103598712014 @default.
• W2010359871 countsByYear W20103598712015 @default.
• W2010359871 countsByYear W20103598712016 @default.
• W2010359871 countsByYear W20103598712017 @default.
• W2010359871 countsByYear W20103598712019 @default.
• W2010359871 countsByYear W20103598712020 @default.
• W2010359871 countsByYear W20103598712021 @default.
• W2010359871 countsByYear W20103598712022 @default.
• W2010359871 crossrefType "journal-article" @default.
• W2010359871 hasAuthorship W2010359871A5003025455 @default.
• W2010359871 hasAuthorship W2010359871A5003945271 @default.
• W2010359871 hasAuthorship W2010359871A5021753814 @default.
• W2010359871 hasAuthorship W2010359871A5022844690 @default.
• W2010359871 hasAuthorship W2010359871A5025910539 @default.
• W2010359871 hasAuthorship W2010359871A5036093168 @default.
• W2010359871 hasAuthorship W2010359871A5051111376 @default.
• W2010359871 hasAuthorship W2010359871A5052546138 @default.
• W2010359871 hasAuthorship W2010359871A5056043869 @default.
• W2010359871 hasAuthorship W2010359871A5059626751 @default.
• W2010359871 hasBestOaLocation W20103598711 @default.
• W2010359871 hasConcept C104317684 @default.
• W2010359871 hasConcept C112212490 @default.
• W2010359871 hasConcept C138626823 @default.
• W2010359871 hasConcept C141231307 @default.
• W2010359871 hasConcept C153911025 @default.
• W2010359871 hasConcept C170627219 @default.
• W2010359871 hasConcept C180754005 @default.
• W2010359871 hasConcept C206936463 @default.
• W2010359871 hasConcept C207936829 @default.
• W2010359871 hasConcept C34957205 @default.
• W2010359871 hasConcept C54355233 @default.
• W2010359871 hasConcept C84597430 @default.
• W2010359871 hasConcept C86803240 @default.
• W2010359871 hasConcept C94671646 @default.
• W2010359871 hasConceptScore W2010359871C104317684 @default.
• W2010359871 hasConceptScore W2010359871C112212490 @default.
• W2010359871 hasConceptScore W2010359871C138626823 @default.
• W2010359871 hasConceptScore W2010359871C141231307 @default.
• W2010359871 hasConceptScore W2010359871C153911025 @default.

• next