FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010371873> ?p ?o ?g. }

• W2010371873 endingPage "358" @default.
• W2010371873 startingPage "357" @default.
• W2010371873 abstract "Psychiatry Research. 21,357-358 Elsevier Letter Subcortical Signal Hyperintensities in Bipolar Patients Detected by MRI To the Editors: Some recent reports have shown increased ventricle-brain ratios (Nasrallah et al., 1984; Pearlson et al., 1984) and altered attenuation values (Coffmanand Nasrallah, 1984; Schle- gal and Kretzschmar, 1987) in the computed tomographic (CT) scans of bipolar patients compared with controls. Using magnetic resonance imaging (MRI), we have exam- ined 15 bipolar patients and 8 controls for the presence of ventricular enlargement and par- enchymal abnormalities. All patients and controls were screened with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version (Endi- cott and Spitzer, 1978), history, and labora- tory and physical examinations. Participants with a history of a neurological disorder, birth trauma, developmental delay, uncon- trolled hypertension, or significant alcohol or drug abuse were excluded. Controls were free of personal and family history of psychi- atric disorder. All screening was completed before the MRI. Ventricular rank and pres- ence of parenchymal abnormalities were evaluated by experienced observers without knowledge of group membership of the images (T.J. and J.R.H., respectively). Sub- cortical white matter abnormalities were defined by an increased signal on mixed T,/ T, and T, weighted images (TR-2,00Oms, TE-25, 70 ms) obtained in axial and coronal planes. Regions of increased signal found normally directly anterior to the frontal horn or posterior to the occipital horn ofthe lateral ventricle were excluded. Fifteen bipolar patients met Research Diagnostic Criteria (Spitzer et al., 1978) for the disorder. However, one patient was excluded from analysis due to the presence of a previously undiagnosed arachnoid cyst dis- placing the left temporal lobe. The remaining @ 1987 Ekvier bipolar patients were 13 males and 1 female. Seven patients were on lithium alone, two were on lithium plus a tricyclic anti- depressant, one was on lithium, benztropine, and fluphenazine HCl, one was on carba- mazepine, and three were unmedicated. One bipolar male had recentlycompletedacourse of electroconvulsive therapy (ECT). Eight males served as controls. The average age of the patients was 38 + 8 years, and that of the controls was 41 f 9 years (NS difference). Eight of the 14 bipolars and none of the controls exhibited white matter abnormali- ties @ 0.90). To our knowledge, this is the first study demonstrating focal parenchymal abnor- malities in bipolar patients using MRI. Further studies are underway to evaluate the relationship of these lesions to performance on tests of cognitive functioning. Scientific Publishers Ireland Ltd." @default.
• W2010371873 created "2016-06-24" @default.
• W2010371873 creator A5058224561 @default.
• W2010371873 creator A5064045531 @default.
• W2010371873 creator A5071645390 @default.
• W2010371873 creator A5076053154 @default.
• W2010371873 creator A5079125637 @default.
• W2010371873 creator A5080015493 @default.
• W2010371873 date "1987-08-01" @default.
• W2010371873 modified "2023-10-15" @default.
• W2010371873 title "Subcortical signal hyperintensities in bipolar patients detected by MRI" @default.
• W2010371873 cites W1974702488 @default.
• W2010371873 cites W2017524325 @default.
• W2010371873 cites W2049165791 @default.
• W2010371873 cites W2059196043 @default.
• W2010371873 cites W2095127857 @default.
• W2010371873 cites W2114613490 @default.
• W2010371873 cites W62361546 @default.
• W2010371873 doi "https://doi.org/10.1016/0165-1781(87)90020-5" @default.
• W2010371873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3628618" @default.
• W2010371873 hasPublicationYear "1987" @default.
• W2010371873 type Work @default.
• W2010371873 sameAs 2010371873 @default.
• W2010371873 citedByCount "83" @default.
• W2010371873 countsByYear W20103718732012 @default.
• W2010371873 countsByYear W20103718732015 @default.
• W2010371873 countsByYear W20103718732016 @default.
• W2010371873 countsByYear W20103718732019 @default.
• W2010371873 crossrefType "journal-article" @default.
• W2010371873 hasAuthorship W2010371873A5058224561 @default.
• W2010371873 hasAuthorship W2010371873A5064045531 @default.
• W2010371873 hasAuthorship W2010371873A5071645390 @default.
• W2010371873 hasAuthorship W2010371873A5076053154 @default.
• W2010371873 hasAuthorship W2010371873A5079125637 @default.
• W2010371873 hasAuthorship W2010371873A5080015493 @default.
• W2010371873 hasBestOaLocation W20103718732 @default.
• W2010371873 hasConcept C121332964 @default.
• W2010371873 hasConcept C126838900 @default.
• W2010371873 hasConcept C143409427 @default.
• W2010371873 hasConcept C146638467 @default.
• W2010371873 hasConcept C15744967 @default.
• W2010371873 hasConcept C169760540 @default.
• W2010371873 hasConcept C2989005 @default.
• W2010371873 hasConcept C46141821 @default.
• W2010371873 hasConcept C71924100 @default.
• W2010371873 hasConceptScore W2010371873C121332964 @default.
• W2010371873 hasConceptScore W2010371873C126838900 @default.
• W2010371873 hasConceptScore W2010371873C143409427 @default.
• W2010371873 hasConceptScore W2010371873C146638467 @default.
• W2010371873 hasConceptScore W2010371873C15744967 @default.
• W2010371873 hasConceptScore W2010371873C169760540 @default.
• W2010371873 hasConceptScore W2010371873C2989005 @default.
• W2010371873 hasConceptScore W2010371873C46141821 @default.
• W2010371873 hasConceptScore W2010371873C71924100 @default.
• W2010371873 hasIssue "4" @default.
• W2010371873 hasLocation W20103718731 @default.
• W2010371873 hasLocation W20103718732 @default.
• W2010371873 hasLocation W20103718733 @default.
• W2010371873 hasOpenAccess W2010371873 @default.
• W2010371873 hasPrimaryLocation W20103718731 @default.
• W2010371873 hasRelatedWork W1991894501 @default.
• W2010371873 hasRelatedWork W2021468470 @default.
• W2010371873 hasRelatedWork W2082419882 @default.
• W2010371873 hasRelatedWork W2090103820 @default.
• W2010371873 hasRelatedWork W2106430568 @default.
• W2010371873 hasRelatedWork W2117421758 @default.
• W2010371873 hasRelatedWork W2135989124 @default.
• W2010371873 hasRelatedWork W2748952813 @default.
• W2010371873 hasRelatedWork W2899084033 @default.
• W2010371873 hasRelatedWork W2911417743 @default.
• W2010371873 hasVolume "21" @default.
• W2010371873 isParatext "false" @default.
• W2010371873 isRetracted "false" @default.
• W2010371873 magId "2010371873" @default.
• W2010371873 workType "article" @default.