Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010372217> ?p ?o ?g. }
- W2010372217 endingPage "601" @default.
- W2010372217 startingPage "593" @default.
- W2010372217 abstract "Inflammation results in the production of free radicals. We evaluated the anti-inflammatory and antioxidant capacity of lipoic acid in an experimental uveitis model upon a subcutaneous injection of endotoxin into Lewis rats. The role of oxidative stress in the endotoxin-induced uveitis model is well-known. Besides, the Th1 response classically performs a central part in the immunopathological process of experimental autoimmune uveitis. Exogenous sources of lipoic acid have been shown to exhibit antioxidant and anti-inflammatory properties. Our results show that lipoic acid treatment plays a preventive role in endotoxin-induced oxidative stress at 24 h post-administration and reduced Th1 lymphocytes-related cytokines by approximately 50-60%. Simultaneously, lipoic acid treatment caused a significant reduction in uveal histopathological grading and in the protein concentration in aqueous humors, but not in cellular infiltration." @default.
- W2010372217 created "2016-06-24" @default.
- W2010372217 creator A5008880843 @default.
- W2010372217 creator A5025195097 @default.
- W2010372217 creator A5033290178 @default.
- W2010372217 creator A5044496196 @default.
- W2010372217 creator A5074773006 @default.
- W2010372217 creator A5087243292 @default.
- W2010372217 date "2013-06-13" @default.
- W2010372217 modified "2023-10-18" @default.
- W2010372217 title "Lipoic acid lessens Th1-mediated inflammation in lipopolysaccharide-induced uveitis reducing selectively Th1 lymphocytes-related cytokines release" @default.
- W2010372217 cites W1553386677 @default.
- W2010372217 cites W1596294096 @default.
- W2010372217 cites W1775749144 @default.
- W2010372217 cites W1897201563 @default.
- W2010372217 cites W1898603768 @default.
- W2010372217 cites W1906015743 @default.
- W2010372217 cites W1917585002 @default.
- W2010372217 cites W1965696818 @default.
- W2010372217 cites W1967892082 @default.
- W2010372217 cites W1970749702 @default.
- W2010372217 cites W1973127776 @default.
- W2010372217 cites W1977180065 @default.
- W2010372217 cites W1978227204 @default.
- W2010372217 cites W1979356762 @default.
- W2010372217 cites W1985312132 @default.
- W2010372217 cites W1998468392 @default.
- W2010372217 cites W1999149231 @default.
- W2010372217 cites W2003949605 @default.
- W2010372217 cites W2006694641 @default.
- W2010372217 cites W2016853025 @default.
- W2010372217 cites W2024279142 @default.
- W2010372217 cites W2028464299 @default.
- W2010372217 cites W2029423245 @default.
- W2010372217 cites W2029974988 @default.
- W2010372217 cites W2036736548 @default.
- W2010372217 cites W2046728427 @default.
- W2010372217 cites W2054870986 @default.
- W2010372217 cites W2059112250 @default.
- W2010372217 cites W2061245081 @default.
- W2010372217 cites W2064170412 @default.
- W2010372217 cites W2067769137 @default.
- W2010372217 cites W2069194257 @default.
- W2010372217 cites W2072299377 @default.
- W2010372217 cites W2077486579 @default.
- W2010372217 cites W2077899403 @default.
- W2010372217 cites W2081055734 @default.
- W2010372217 cites W2085534129 @default.
- W2010372217 cites W2089547931 @default.
- W2010372217 cites W2092134362 @default.
- W2010372217 cites W2092890519 @default.
- W2010372217 cites W2095424605 @default.
- W2010372217 cites W2102131116 @default.
- W2010372217 cites W2110607710 @default.
- W2010372217 cites W2113588185 @default.
- W2010372217 cites W2118626596 @default.
- W2010372217 cites W2127685167 @default.
- W2010372217 cites W2128149258 @default.
- W2010372217 cites W2129305481 @default.
- W2010372217 cites W2137598362 @default.
- W2010372217 cites W2141304647 @default.
- W2010372217 cites W2141868068 @default.
- W2010372217 cites W2150546396 @default.
- W2010372217 cites W2152331398 @default.
- W2010372217 cites W2156813826 @default.
- W2010372217 cites W2160397772 @default.
- W2010372217 cites W2162810808 @default.
- W2010372217 cites W2165626477 @default.
- W2010372217 cites W2165781405 @default.
- W2010372217 cites W2920938799 @default.
- W2010372217 doi "https://doi.org/10.3109/10715762.2013.805882" @default.
- W2010372217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23678888" @default.
- W2010372217 hasPublicationYear "2013" @default.
- W2010372217 type Work @default.
- W2010372217 sameAs 2010372217 @default.
- W2010372217 citedByCount "9" @default.
- W2010372217 countsByYear W20103722172014 @default.
- W2010372217 countsByYear W20103722172015 @default.
- W2010372217 countsByYear W20103722172016 @default.
- W2010372217 countsByYear W20103722172018 @default.
- W2010372217 countsByYear W20103722172021 @default.
- W2010372217 countsByYear W20103722172022 @default.
- W2010372217 countsByYear W20103722172023 @default.
- W2010372217 crossrefType "journal-article" @default.
- W2010372217 hasAuthorship W2010372217A5008880843 @default.
- W2010372217 hasAuthorship W2010372217A5025195097 @default.
- W2010372217 hasAuthorship W2010372217A5033290178 @default.
- W2010372217 hasAuthorship W2010372217A5044496196 @default.
- W2010372217 hasAuthorship W2010372217A5074773006 @default.
- W2010372217 hasAuthorship W2010372217A5087243292 @default.
- W2010372217 hasConcept C164027704 @default.
- W2010372217 hasConcept C185592680 @default.
- W2010372217 hasConcept C203014093 @default.
- W2010372217 hasConcept C2776151105 @default.
- W2010372217 hasConcept C2776194053 @default.
- W2010372217 hasConcept C2776914184 @default.
- W2010372217 hasConcept C2778004101 @default.
- W2010372217 hasConcept C2778690821 @default.