Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010378809> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2010378809 endingPage "567" @default.
- W2010378809 startingPage "560" @default.
- W2010378809 abstract "Background: Tumor cells can escape complement‐dependent cytotoxicity (CDC) by expressing complement restriction factors (CRFs), CD46, CD55 and CD59. CRF‐expression in non‐neoplastic mucosa of the head and neck was compared with biopsies of the head and neck squamous cell carcinoma (HNSCC) and cell lines derived from oral squamous cell carcinomas (OSCC). Methods: Normal mucosa and HNSCC tumor tissue (poor, moderate, or well differentiated) specimens were immunostained with anti‐CRF monoclonal antibodies. Immunostaining of the OSCC cell lines (SCC12 and SCC71) was examined under laser scan fluorescence microscopy. Results: CD46, CD55 and CD59 were highly expressed in HNSCC cells including T1/T2N0M0 stages. The CRF expression was much lower or absent in non‐neoplastic squamous epithelia or in the submucosa of both normal and tumor tissues. Conclusions: Enhanced staining of tumor tissues at stages T1/T2 indicates that the CRFs are overexpressed by primary tumors before metastasis to either lymph nodes or organs (N0M0 stage) suggesting that CRFs are formed early during tumorigenesis." @default.
- W2010378809 created "2016-06-24" @default.
- W2010378809 creator A5069348447 @default.
- W2010378809 creator A5088873663 @default.
- W2010378809 date "2006-09-12" @default.
- W2010378809 modified "2023-10-11" @default.
- W2010378809 title "Expression of complement restriction factors (CD46, CD55 & CD59) in head and neck squamous cell carcinomas" @default.
- W2010378809 cites W1548253679 @default.
- W2010378809 cites W1561613355 @default.
- W2010378809 cites W1966151215 @default.
- W2010378809 cites W1971836390 @default.
- W2010378809 cites W1983872339 @default.
- W2010378809 cites W1990479670 @default.
- W2010378809 cites W1993945079 @default.
- W2010378809 cites W2002129746 @default.
- W2010378809 cites W2009562082 @default.
- W2010378809 cites W2009600311 @default.
- W2010378809 cites W2034760871 @default.
- W2010378809 cites W2034844348 @default.
- W2010378809 cites W2035215771 @default.
- W2010378809 cites W2036674239 @default.
- W2010378809 cites W2046349450 @default.
- W2010378809 cites W2056477082 @default.
- W2010378809 cites W2078032056 @default.
- W2010378809 cites W2079258299 @default.
- W2010378809 cites W2090043309 @default.
- W2010378809 cites W2110108677 @default.
- W2010378809 cites W2116280398 @default.
- W2010378809 cites W2138683401 @default.
- W2010378809 cites W2412500346 @default.
- W2010378809 cites W2440004261 @default.
- W2010378809 doi "https://doi.org/10.1111/j.1600-0714.2006.00466.x" @default.
- W2010378809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16968237" @default.
- W2010378809 hasPublicationYear "2006" @default.
- W2010378809 type Work @default.
- W2010378809 sameAs 2010378809 @default.
- W2010378809 citedByCount "27" @default.
- W2010378809 countsByYear W20103788092013 @default.
- W2010378809 countsByYear W20103788092014 @default.
- W2010378809 countsByYear W20103788092015 @default.
- W2010378809 countsByYear W20103788092016 @default.
- W2010378809 countsByYear W20103788092017 @default.
- W2010378809 countsByYear W20103788092019 @default.
- W2010378809 countsByYear W20103788092020 @default.
- W2010378809 countsByYear W20103788092022 @default.
- W2010378809 crossrefType "journal-article" @default.
- W2010378809 hasAuthorship W2010378809A5069348447 @default.
- W2010378809 hasAuthorship W2010378809A5088873663 @default.
- W2010378809 hasConcept C111684460 @default.
- W2010378809 hasConcept C121608353 @default.
- W2010378809 hasConcept C126322002 @default.
- W2010378809 hasConcept C142724271 @default.
- W2010378809 hasConcept C159654299 @default.
- W2010378809 hasConcept C184404459 @default.
- W2010378809 hasConcept C203014093 @default.
- W2010378809 hasConcept C204232928 @default.
- W2010378809 hasConcept C2776530083 @default.
- W2010378809 hasConcept C2776833033 @default.
- W2010378809 hasConcept C4224716 @default.
- W2010378809 hasConcept C502942594 @default.
- W2010378809 hasConcept C71924100 @default.
- W2010378809 hasConcept C86803240 @default.
- W2010378809 hasConceptScore W2010378809C111684460 @default.
- W2010378809 hasConceptScore W2010378809C121608353 @default.
- W2010378809 hasConceptScore W2010378809C126322002 @default.
- W2010378809 hasConceptScore W2010378809C142724271 @default.
- W2010378809 hasConceptScore W2010378809C159654299 @default.
- W2010378809 hasConceptScore W2010378809C184404459 @default.
- W2010378809 hasConceptScore W2010378809C203014093 @default.
- W2010378809 hasConceptScore W2010378809C204232928 @default.
- W2010378809 hasConceptScore W2010378809C2776530083 @default.
- W2010378809 hasConceptScore W2010378809C2776833033 @default.
- W2010378809 hasConceptScore W2010378809C4224716 @default.
- W2010378809 hasConceptScore W2010378809C502942594 @default.
- W2010378809 hasConceptScore W2010378809C71924100 @default.
- W2010378809 hasConceptScore W2010378809C86803240 @default.
- W2010378809 hasIssue "9" @default.
- W2010378809 hasLocation W20103788091 @default.
- W2010378809 hasLocation W20103788092 @default.
- W2010378809 hasOpenAccess W2010378809 @default.
- W2010378809 hasPrimaryLocation W20103788091 @default.
- W2010378809 hasRelatedWork W110523806 @default.
- W2010378809 hasRelatedWork W1546067550 @default.
- W2010378809 hasRelatedWork W1979893467 @default.
- W2010378809 hasRelatedWork W2001495175 @default.
- W2010378809 hasRelatedWork W2056351008 @default.
- W2010378809 hasRelatedWork W2057390952 @default.
- W2010378809 hasRelatedWork W2347823473 @default.
- W2010378809 hasRelatedWork W2512703498 @default.
- W2010378809 hasRelatedWork W2924722371 @default.
- W2010378809 hasRelatedWork W3134667467 @default.
- W2010378809 hasVolume "35" @default.
- W2010378809 isParatext "false" @default.
- W2010378809 isRetracted "false" @default.
- W2010378809 magId "2010378809" @default.
- W2010378809 workType "article" @default.