Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010390384> ?p ?o ?g. }
- W2010390384 endingPage "389" @default.
- W2010390384 startingPage "386" @default.
- W2010390384 abstract "Hepatocyte growth factor (HGF) is expressed in placental syncitium and fetal organs and acts as a mitogen, motogen, and morphogen in vitro, suggesting a role in fetal growth and development. We aimed to examine the correlates of serum HGF in human cord blood. HGF was measured by ELISA using recombinant human HGF and mouse MAb to recombinant human HGF (Immunology Institute, Tokyo). Umbilical vein blood was collected prospectively at 148 deliveries including 94 normal pregnancies and 54 pregnancies complicated by medical conditions, primarily diabetes mellitus and pregnancy-induced hypertension. Growth parameters, gestation, pregnancy history, and perinatal events were recorded. Sera from 54 adolescents and 32 adult controls were also analyzed. Cord HGF [0.97 (0.66-1.33) ng/mL] [median (25-75 percentile)] was higher than HGF levels in adolescent sera [0.28 (0.21-0.35) ng/mL, p < 0.0001] and adult control sera [0.23 (0.14-0.31) ng/mL, p < 0.0001]. Cord HGF correlated with gestational age (r = 0.42, p = 0.0001) in normal pregnancies, with term babies (n = 69) having higher cord HGF than babies less than 37 wk of gestation (n = 25) [1.11 (0.78-1.45), 0.78 (0.46-1.03) ng/mL, p = 0.0007]. However, there was no relationship between gestation and cord HGF in complicated pregnancies. Cord HGF did not differ at term between appropriate for gestational age babies and small for gestational age babies. There were no independent correlations between cord HGF and birth weight, birth length and placental weight. We provide evidence for the first time that cord HGF levels are high and relate to gestation in normal pregnancies. HGF may have a significant role in fetal development during pregnancy." @default.
- W2010390384 created "2016-06-24" @default.
- W2010390384 creator A5024493245 @default.
- W2010390384 creator A5046948958 @default.
- W2010390384 creator A5056508229 @default.
- W2010390384 creator A5063153318 @default.
- W2010390384 creator A5066105917 @default.
- W2010390384 creator A5074305133 @default.
- W2010390384 date "1996-03-01" @default.
- W2010390384 modified "2023-10-18" @default.
- W2010390384 title "Relationship of Hepatocyte Growth Factor in Human Umbilical Vein Serum to Gestational Age in Normal Pregnancies" @default.
- W2010390384 cites W1950578150 @default.
- W2010390384 cites W1952532421 @default.
- W2010390384 cites W1965069579 @default.
- W2010390384 cites W1975034079 @default.
- W2010390384 cites W1995644684 @default.
- W2010390384 cites W2005638713 @default.
- W2010390384 cites W2005782838 @default.
- W2010390384 cites W2013641497 @default.
- W2010390384 cites W2017059447 @default.
- W2010390384 cites W2017458919 @default.
- W2010390384 cites W2022217882 @default.
- W2010390384 cites W2022527563 @default.
- W2010390384 cites W2032511791 @default.
- W2010390384 cites W2035174231 @default.
- W2010390384 cites W2038555949 @default.
- W2010390384 cites W2043671544 @default.
- W2010390384 cites W2047099628 @default.
- W2010390384 cites W2052915894 @default.
- W2010390384 cites W2053311718 @default.
- W2010390384 cites W2054042846 @default.
- W2010390384 cites W2059947041 @default.
- W2010390384 cites W2061917954 @default.
- W2010390384 cites W2080356314 @default.
- W2010390384 cites W2087911913 @default.
- W2010390384 cites W2092920460 @default.
- W2010390384 cites W2102969844 @default.
- W2010390384 cites W2108146910 @default.
- W2010390384 cites W2125508002 @default.
- W2010390384 cites W2147150467 @default.
- W2010390384 cites W2151005088 @default.
- W2010390384 cites W4238813317 @default.
- W2010390384 cites W4247617218 @default.
- W2010390384 cites W4247641001 @default.
- W2010390384 doi "https://doi.org/10.1203/00006450-199603000-00002" @default.
- W2010390384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8929855" @default.
- W2010390384 hasPublicationYear "1996" @default.
- W2010390384 type Work @default.
- W2010390384 sameAs 2010390384 @default.
- W2010390384 citedByCount "12" @default.
- W2010390384 countsByYear W20103903842012 @default.
- W2010390384 countsByYear W20103903842022 @default.
- W2010390384 crossrefType "journal-article" @default.
- W2010390384 hasAuthorship W2010390384A5024493245 @default.
- W2010390384 hasAuthorship W2010390384A5046948958 @default.
- W2010390384 hasAuthorship W2010390384A5056508229 @default.
- W2010390384 hasAuthorship W2010390384A5063153318 @default.
- W2010390384 hasAuthorship W2010390384A5066105917 @default.
- W2010390384 hasAuthorship W2010390384A5074305133 @default.
- W2010390384 hasBestOaLocation W20103903841 @default.
- W2010390384 hasConcept C126322002 @default.
- W2010390384 hasConcept C134018914 @default.
- W2010390384 hasConcept C16685009 @default.
- W2010390384 hasConcept C170493617 @default.
- W2010390384 hasConcept C172680121 @default.
- W2010390384 hasConcept C203014093 @default.
- W2010390384 hasConcept C2776953305 @default.
- W2010390384 hasConcept C2776955114 @default.
- W2010390384 hasConcept C2776996007 @default.
- W2010390384 hasConcept C2778376644 @default.
- W2010390384 hasConcept C2779234561 @default.
- W2010390384 hasConcept C2780914630 @default.
- W2010390384 hasConcept C46973012 @default.
- W2010390384 hasConcept C54355233 @default.
- W2010390384 hasConcept C66322754 @default.
- W2010390384 hasConcept C71924100 @default.
- W2010390384 hasConcept C86803240 @default.
- W2010390384 hasConceptScore W2010390384C126322002 @default.
- W2010390384 hasConceptScore W2010390384C134018914 @default.
- W2010390384 hasConceptScore W2010390384C16685009 @default.
- W2010390384 hasConceptScore W2010390384C170493617 @default.
- W2010390384 hasConceptScore W2010390384C172680121 @default.
- W2010390384 hasConceptScore W2010390384C203014093 @default.
- W2010390384 hasConceptScore W2010390384C2776953305 @default.
- W2010390384 hasConceptScore W2010390384C2776955114 @default.
- W2010390384 hasConceptScore W2010390384C2776996007 @default.
- W2010390384 hasConceptScore W2010390384C2778376644 @default.
- W2010390384 hasConceptScore W2010390384C2779234561 @default.
- W2010390384 hasConceptScore W2010390384C2780914630 @default.
- W2010390384 hasConceptScore W2010390384C46973012 @default.
- W2010390384 hasConceptScore W2010390384C54355233 @default.
- W2010390384 hasConceptScore W2010390384C66322754 @default.
- W2010390384 hasConceptScore W2010390384C71924100 @default.
- W2010390384 hasConceptScore W2010390384C86803240 @default.
- W2010390384 hasIssue "3" @default.
- W2010390384 hasLocation W20103903841 @default.
- W2010390384 hasLocation W20103903842 @default.
- W2010390384 hasOpenAccess W2010390384 @default.