FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010407408> ?p ?o ?g. }

• W2010407408 endingPage "167" @default.
• W2010407408 startingPage "159" @default.
• W2010407408 abstract "Human exposure to organic solvents is often complicated by ethanol ingestion and the literature is replete with demonstrations of metabolic interactions between ethanol and organic solvents at a pharmacokinetic level. Because of the possible modulation of xylene toxicity by ethanol consumption, the present group of studies characterizes the effect of ethanol on the p-xylene-induced decrease in axonal transport in the rat optic system previously reported by our laboratory. Long-Evans, hooded, male rats were divided randomly into two groups: those receiving 10% ethanol in their drinking water and those receiving water only. These two groups were further subdivided into two groups which were either exposed by inhalation to 1600 ppm p-xylene for 6 h/day, 5 days/week for 8 exposure-days or were treated identically except that they were exposed to air while in the inhalation chambers. The ethanol-drinking rats were given ethanol 6 days prior to and on the days of the inhalation exposure. Immediately after removal from the inhalation chambers on the last exposure day, the animals were injected intraocularly with [35S]methionine and [3H]fucose to measure the synthesis and rapid axonal transport of proteins and glycoproteins, respectively, in the retinal ganglion cells. The animals were sacrificed 20 h later, and the amount of radioactivity in different areas of the retinal ganglion cells was determined by liquid scintillation counting. As in previous experiments, the xylene exposure group showed a significant reduction in axonal transport of proteins and glycoproteins, whereas the ethanol exposure alone produced no significant reductions in the transport of either proteins or glycoproteins. In the animals receiving both ethanol and xylene, however, the ethanol treatment prevented the decreased transport characteristic of the xylene only animals, i.e. in all areas of the optic projections the level of transport were similar to the level present in the control groups. These data suggest that the xylene-induced reduction in rapid axonal transport was reversed (or prevented) by subacute ethanol consumption." @default.
• W2010407408 created "2016-06-24" @default.
• W2010407408 creator A5021072254 @default.
• W2010407408 creator A5022937815 @default.
• W2010407408 creator A5041676888 @default.
• W2010407408 date "1992-11-01" @default.
• W2010407408 modified "2023-09-28" @default.
• W2010407408 title "Subacute ethanol consumption reverses p-xylene-induced decreases in axonal transport" @default.
• W2010407408 cites W1581536771 @default.
• W2010407408 cites W1934227057 @default.
• W2010407408 cites W1988843296 @default.
• W2010407408 cites W199620032 @default.
• W2010407408 cites W1998486206 @default.
• W2010407408 cites W2005434453 @default.
• W2010407408 cites W2006773457 @default.
• W2010407408 cites W2016040165 @default.
• W2010407408 cites W2016848746 @default.
• W2010407408 cites W2017057682 @default.
• W2010407408 cites W2018613448 @default.
• W2010407408 cites W2019809520 @default.
• W2010407408 cites W2028758833 @default.
• W2010407408 cites W2029332281 @default.
• W2010407408 cites W2031104940 @default.
• W2010407408 cites W2037888311 @default.
• W2010407408 cites W2044578186 @default.
• W2010407408 cites W2072421800 @default.
• W2010407408 cites W2073271116 @default.
• W2010407408 cites W2077661380 @default.
• W2010407408 cites W2085243205 @default.
• W2010407408 cites W2090364551 @default.
• W2010407408 cites W2090558615 @default.
• W2010407408 cites W2092310033 @default.
• W2010407408 cites W2092903922 @default.
• W2010407408 cites W2113861816 @default.
• W2010407408 cites W2145837734 @default.
• W2010407408 cites W2148014345 @default.
• W2010407408 cites W2261522463 @default.
• W2010407408 cites W2312523884 @default.
• W2010407408 cites W2328974317 @default.
• W2010407408 cites W2409089316 @default.
• W2010407408 cites W2415242142 @default.
• W2010407408 cites W2417856636 @default.
• W2010407408 cites W2473237648 @default.
• W2010407408 doi "https://doi.org/10.1016/0300-483x(92)90154-7" @default.
• W2010407408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1281343" @default.
• W2010407408 hasPublicationYear "1992" @default.
• W2010407408 type Work @default.
• W2010407408 sameAs 2010407408 @default.
• W2010407408 citedByCount "7" @default.
• W2010407408 countsByYear W20104074082012 @default.
• W2010407408 countsByYear W20104074082015 @default.
• W2010407408 countsByYear W20104074082016 @default.
• W2010407408 countsByYear W20104074082020 @default.
• W2010407408 crossrefType "journal-article" @default.
• W2010407408 hasAuthorship W2010407408A5021072254 @default.
• W2010407408 hasAuthorship W2010407408A5022937815 @default.
• W2010407408 hasAuthorship W2010407408A5041676888 @default.
• W2010407408 hasConcept C105702510 @default.
• W2010407408 hasConcept C126322002 @default.
• W2010407408 hasConcept C134018914 @default.
• W2010407408 hasConcept C178790620 @default.
• W2010407408 hasConcept C185592680 @default.
• W2010407408 hasConcept C2776954882 @default.
• W2010407408 hasConcept C2777691172 @default.
• W2010407408 hasConcept C2779777708 @default.
• W2010407408 hasConcept C2779896714 @default.
• W2010407408 hasConcept C2780161600 @default.
• W2010407408 hasConcept C29730261 @default.
• W2010407408 hasConcept C33070731 @default.
• W2010407408 hasConcept C42219234 @default.
• W2010407408 hasConcept C55493867 @default.
• W2010407408 hasConcept C70192387 @default.
• W2010407408 hasConcept C71924100 @default.
• W2010407408 hasConcept C86803240 @default.
• W2010407408 hasConcept C98274493 @default.
• W2010407408 hasConceptScore W2010407408C105702510 @default.
• W2010407408 hasConceptScore W2010407408C126322002 @default.
• W2010407408 hasConceptScore W2010407408C134018914 @default.
• W2010407408 hasConceptScore W2010407408C178790620 @default.
• W2010407408 hasConceptScore W2010407408C185592680 @default.
• W2010407408 hasConceptScore W2010407408C2776954882 @default.
• W2010407408 hasConceptScore W2010407408C2777691172 @default.
• W2010407408 hasConceptScore W2010407408C2779777708 @default.
• W2010407408 hasConceptScore W2010407408C2779896714 @default.
• W2010407408 hasConceptScore W2010407408C2780161600 @default.
• W2010407408 hasConceptScore W2010407408C29730261 @default.
• W2010407408 hasConceptScore W2010407408C33070731 @default.
• W2010407408 hasConceptScore W2010407408C42219234 @default.
• W2010407408 hasConceptScore W2010407408C55493867 @default.
• W2010407408 hasConceptScore W2010407408C70192387 @default.
• W2010407408 hasConceptScore W2010407408C71924100 @default.
• W2010407408 hasConceptScore W2010407408C86803240 @default.
• W2010407408 hasConceptScore W2010407408C98274493 @default.
• W2010407408 hasIssue "2" @default.
• W2010407408 hasLocation W20104074081 @default.
• W2010407408 hasLocation W20104074082 @default.
• W2010407408 hasOpenAccess W2010407408 @default.
• W2010407408 hasPrimaryLocation W20104074081 @default.

• next