FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010410987> ?p ?o ?g. }

• W2010410987 endingPage "310" @default.
• W2010410987 startingPage "303" @default.
• W2010410987 abstract "Objective To determine iron‐induced free radical damage in fetal rhesus haemolytic disease (RHD) before and after repeated intrauterine red blood cell transfusions and its relation to hydrops fetalis. Design Prospective, observational study. Setting Department of Obstetrics, Leiden University Medical Centre, the Netherlands. Population Fifty anaemic fetuses, including 13 hydropic ones, 9 preterm and 12 term neonates and 8 female non‐pregnant adults. Methods Venous blood plasma samples were collected from 50 fetuses suffering from RHD preliminary to the first, and if appropriate, subsequent intrauterine red blood cell transfusions for determination of iron status including non‐protein‐bound iron (NPBI) and iron‐binding primary antioxidant proteins, total plasma anti‐oxidant capacity and its contributing secondary antioxidants (e.g. vitamin C, uric acid, sulphydryl groups and peroxidation products). Results were compared with values of healthy preterm and term neonates directly at birth and adult controls. Within the fetal haemolytic group, 13 hydropic fetuses were analysed as a separate group. Main outcome measures Non‐protein‐bound iron, antioxidants, total antioxidant capacity and peroxidation products. Sub analysis of the outcome measures of the hydropic fetuses. Results RHD fetuses had at initial cordocentesis a significantly higher NPBI level and a significantly lower total plasma antioxidant capacity than control babies and adults. Their vitamin C tended to be more oxidised but lipid peroxidation had not increased, when compared with preterm babies. The repeated intrauterine red blood cell transfusions had a positive effect on the total antioxidant capacity of plasma and did not increase the concentration of NPBI. The hydropic fetuses, who had higher NPBI concentrations and lower plasma protein concentrations and total antioxidant capacity, did not show more peroxidation products in plasma than the non‐hydropic fetuses. Fetuses without reversal of hydrops despite intrauterine transfusions showed decreasing levels of proteins with subsequent transfusions but peroxidation products remained constant. Conclusion Repeated intrauterine red blood cell transfusions do not lead to free radical damage in the fetus in utero . Iron‐induced free radical activity does not appear to play a causative role in the proceeding of hydrops fetalis in RHD." @default.
• W2010410987 created "2016-06-24" @default.
• W2010410987 creator A5033018392 @default.
• W2010410987 creator A5048574728 @default.
• W2010410987 creator A5050355175 @default.
• W2010410987 creator A5061682020 @default.
• W2010410987 creator A5090264340 @default.
• W2010410987 date "2004-03-04" @default.
• W2010410987 modified "2023-10-15" @default.
• W2010410987 title "Non-protein-bound iron and free radical damage in fetuses with rhesus haemolytic disease: influence of intrauterine transfusions" @default.
• W2010410987 cites W128506444 @default.
• W2010410987 cites W1536410957 @default.
• W2010410987 cites W1590090751 @default.
• W2010410987 cites W1951419200 @default.
• W2010410987 cites W1967678385 @default.
• W2010410987 cites W1969687883 @default.
• W2010410987 cites W1970446188 @default.
• W2010410987 cites W1971117013 @default.
• W2010410987 cites W1972069137 @default.
• W2010410987 cites W1974283996 @default.
• W2010410987 cites W1975242694 @default.
• W2010410987 cites W1975577170 @default.
• W2010410987 cites W1979371797 @default.
• W2010410987 cites W1981897333 @default.
• W2010410987 cites W1985283373 @default.
• W2010410987 cites W1989534675 @default.
• W2010410987 cites W1992815766 @default.
• W2010410987 cites W2000721848 @default.
• W2010410987 cites W2005894414 @default.
• W2010410987 cites W2007944111 @default.
• W2010410987 cites W2010755663 @default.
• W2010410987 cites W2019926170 @default.
• W2010410987 cites W2022196444 @default.
• W2010410987 cites W2026785305 @default.
• W2010410987 cites W2066580614 @default.
• W2010410987 cites W2068370664 @default.
• W2010410987 cites W2069994257 @default.
• W2010410987 cites W2085427044 @default.
• W2010410987 cites W2085873893 @default.
• W2010410987 cites W2093942585 @default.
• W2010410987 cites W2098439388 @default.
• W2010410987 cites W2109977819 @default.
• W2010410987 cites W2118483146 @default.
• W2010410987 cites W2133443708 @default.
• W2010410987 cites W2136118922 @default.
• W2010410987 cites W2156523657 @default.
• W2010410987 cites W2413091771 @default.
• W2010410987 cites W2467695578 @default.
• W2010410987 doi "https://doi.org/10.1111/j.1471-0528.2004.00072.x" @default.
• W2010410987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15008763" @default.
• W2010410987 hasPublicationYear "2004" @default.
• W2010410987 type Work @default.
• W2010410987 sameAs 2010410987 @default.
• W2010410987 citedByCount "6" @default.
• W2010410987 countsByYear W20104109872015 @default.
• W2010410987 countsByYear W20104109872018 @default.
• W2010410987 crossrefType "journal-article" @default.
• W2010410987 hasAuthorship W2010410987A5033018392 @default.
• W2010410987 hasAuthorship W2010410987A5048574728 @default.
• W2010410987 hasAuthorship W2010410987A5050355175 @default.
• W2010410987 hasAuthorship W2010410987A5061682020 @default.
• W2010410987 hasAuthorship W2010410987A5090264340 @default.
• W2010410987 hasConcept C126322002 @default.
• W2010410987 hasConcept C131872663 @default.
• W2010410987 hasConcept C172680121 @default.
• W2010410987 hasConcept C185592680 @default.
• W2010410987 hasConcept C2776151105 @default.
• W2010410987 hasConcept C2776557347 @default.
• W2010410987 hasConcept C2777551382 @default.
• W2010410987 hasConcept C2777674756 @default.
• W2010410987 hasConcept C2778004101 @default.
• W2010410987 hasConcept C2779234561 @default.
• W2010410987 hasConcept C2780022331 @default.
• W2010410987 hasConcept C2780829032 @default.
• W2010410987 hasConcept C2908647359 @default.
• W2010410987 hasConcept C42407357 @default.
• W2010410987 hasConcept C43044207 @default.
• W2010410987 hasConcept C54355233 @default.
• W2010410987 hasConcept C55493867 @default.
• W2010410987 hasConcept C71924100 @default.
• W2010410987 hasConcept C86803240 @default.
• W2010410987 hasConcept C99454951 @default.
• W2010410987 hasConceptScore W2010410987C126322002 @default.
• W2010410987 hasConceptScore W2010410987C131872663 @default.
• W2010410987 hasConceptScore W2010410987C172680121 @default.
• W2010410987 hasConceptScore W2010410987C185592680 @default.
• W2010410987 hasConceptScore W2010410987C2776151105 @default.
• W2010410987 hasConceptScore W2010410987C2776557347 @default.
• W2010410987 hasConceptScore W2010410987C2777551382 @default.
• W2010410987 hasConceptScore W2010410987C2777674756 @default.
• W2010410987 hasConceptScore W2010410987C2778004101 @default.
• W2010410987 hasConceptScore W2010410987C2779234561 @default.
• W2010410987 hasConceptScore W2010410987C2780022331 @default.
• W2010410987 hasConceptScore W2010410987C2780829032 @default.
• W2010410987 hasConceptScore W2010410987C2908647359 @default.
• W2010410987 hasConceptScore W2010410987C42407357 @default.
• W2010410987 hasConceptScore W2010410987C43044207 @default.
• W2010410987 hasConceptScore W2010410987C54355233 @default.

• next