FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010412192> ?p ?o ?g. }

• W2010412192 endingPage "190" @default.
• W2010412192 startingPage "182" @default.
• W2010412192 abstract "Dab2, first identified as a tumor suppressor in ovarian cancerous cells and tissues, is an adaptor protein involved in several signal transduction pathways. Our previous studies of mouse embryos have shown that Dab2 is expressed in the early developing central nervous system and that knockdown of the protein expression perturbs the normal development of the neural tube. In this study, we investigated Dab2 expression in the human fetal hippocampus and temporal, sensory, visual, motor and frontal cortices from 12 to 32 weeks of gestation with a specific immunohistochemical staining method. The hippocampus showed the strongest Dab2 expression among all the brain regions examined. Within the hippocampus, Dab2 expression was first detected at 12–14 weeks in all cellular layers with varying intensities, and the highest level of expression was observed in the pyramidal layer at 26–28 weeks. In the temporal cortex, Dab2 was also expressed in all cellular layers at 12–14 weeks, and its expression peaked at 18–20 weeks and then became weaker at 26–32 weeks. The expression pattern was different in the sensory cortex: the expression was the strongest at 12–14 weeks and then gradually reduced with age. In the visual cortex, Dab2 expression was mainly localized in the marginal zone, upper cortical plate and subcortical layers, whereas the motor and frontal cortices exhibited only low levels of Dab2 expression mostly in the subcortical layers. Our results demonstrated a specific spatiotemporal pattern of Dab2 expression in the human fetal hippocampus and neocortex, implicating roles of Dab2 in the early development of the human brain." @default.
• W2010412192 created "2016-06-24" @default.
• W2010412192 creator A5010693778 @default.
• W2010412192 creator A5023760491 @default.
• W2010412192 creator A5049823634 @default.
• W2010412192 creator A5061273891 @default.
• W2010412192 creator A5063609958 @default.
• W2010412192 date "2008-01-01" @default.
• W2010412192 modified "2023-09-28" @default.
• W2010412192 title "Expression of Dab2, a Tumor Suppressor, in the Human Fetal Hippocampus and Neocortex" @default.
• W2010412192 cites W1969945005 @default.
• W2010412192 cites W1972114425 @default.
• W2010412192 cites W1984267414 @default.
• W2010412192 cites W1993169452 @default.
• W2010412192 cites W1996556707 @default.
• W2010412192 cites W2001056499 @default.
• W2010412192 cites W2002390599 @default.
• W2010412192 cites W2005841227 @default.
• W2010412192 cites W2006778172 @default.
• W2010412192 cites W2007778785 @default.
• W2010412192 cites W2015801933 @default.
• W2010412192 cites W2023324594 @default.
• W2010412192 cites W2026214573 @default.
• W2010412192 cites W2032107473 @default.
• W2010412192 cites W2032408124 @default.
• W2010412192 cites W2032742540 @default.
• W2010412192 cites W2035843228 @default.
• W2010412192 cites W2037293612 @default.
• W2010412192 cites W2040545836 @default.
• W2010412192 cites W2043779556 @default.
• W2010412192 cites W2044342287 @default.
• W2010412192 cites W2048404650 @default.
• W2010412192 cites W2064683425 @default.
• W2010412192 cites W2070369144 @default.
• W2010412192 cites W2075358654 @default.
• W2010412192 cites W2075779574 @default.
• W2010412192 cites W2079918807 @default.
• W2010412192 cites W2082138473 @default.
• W2010412192 cites W2087567898 @default.
• W2010412192 cites W2087954391 @default.
• W2010412192 cites W2094515022 @default.
• W2010412192 cites W2119766505 @default.
• W2010412192 cites W2120777351 @default.
• W2010412192 cites W2120982408 @default.
• W2010412192 cites W2128500531 @default.
• W2010412192 cites W2148601705 @default.
• W2010412192 cites W2151498008 @default.
• W2010412192 cites W2162321314 @default.
• W2010412192 cites W2164710064 @default.
• W2010412192 cites W2611021121 @default.
• W2010412192 doi "https://doi.org/10.1159/000276995" @default.
• W2010412192 hasPublicationYear "2008" @default.
• W2010412192 type Work @default.
• W2010412192 sameAs 2010412192 @default.
• W2010412192 citedByCount "1" @default.
• W2010412192 countsByYear W20104121922021 @default.
• W2010412192 crossrefType "journal-article" @default.
• W2010412192 hasAuthorship W2010412192A5010693778 @default.
• W2010412192 hasAuthorship W2010412192A5023760491 @default.
• W2010412192 hasAuthorship W2010412192A5049823634 @default.
• W2010412192 hasAuthorship W2010412192A5061273891 @default.
• W2010412192 hasAuthorship W2010412192A5063609958 @default.
• W2010412192 hasConcept C169760540 @default.
• W2010412192 hasConcept C173396325 @default.
• W2010412192 hasConcept C2777222312 @default.
• W2010412192 hasConcept C2777348757 @default.
• W2010412192 hasConcept C2779409897 @default.
• W2010412192 hasConcept C2781041448 @default.
• W2010412192 hasConcept C2781161787 @default.
• W2010412192 hasConcept C54355233 @default.
• W2010412192 hasConcept C81885089 @default.
• W2010412192 hasConcept C86803240 @default.
• W2010412192 hasConcept C95444343 @default.
• W2010412192 hasConceptScore W2010412192C169760540 @default.
• W2010412192 hasConceptScore W2010412192C173396325 @default.
• W2010412192 hasConceptScore W2010412192C2777222312 @default.
• W2010412192 hasConceptScore W2010412192C2777348757 @default.
• W2010412192 hasConceptScore W2010412192C2779409897 @default.
• W2010412192 hasConceptScore W2010412192C2781041448 @default.
• W2010412192 hasConceptScore W2010412192C2781161787 @default.
• W2010412192 hasConceptScore W2010412192C54355233 @default.
• W2010412192 hasConceptScore W2010412192C81885089 @default.
• W2010412192 hasConceptScore W2010412192C86803240 @default.
• W2010412192 hasConceptScore W2010412192C95444343 @default.
• W2010412192 hasIssue "4" @default.
• W2010412192 hasLocation W20104121921 @default.
• W2010412192 hasOpenAccess W2010412192 @default.
• W2010412192 hasPrimaryLocation W20104121921 @default.
• W2010412192 hasRelatedWork W1526114854 @default.
• W2010412192 hasRelatedWork W175074270 @default.
• W2010412192 hasRelatedWork W1998428883 @default.
• W2010412192 hasRelatedWork W2036485506 @default.
• W2010412192 hasRelatedWork W2074478341 @default.
• W2010412192 hasRelatedWork W2097604510 @default.
• W2010412192 hasRelatedWork W2123073409 @default.
• W2010412192 hasRelatedWork W2131139893 @default.
• W2010412192 hasRelatedWork W3010706669 @default.
• W2010412192 hasRelatedWork W4252929770 @default.

• next