FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010425523> ?p ?o ?g. }

• W2010425523 endingPage "p65" @default.
• W2010425523 startingPage "p57" @default.
• W2010425523 abstract "<i>Background:</i>L-Arginine (L-arg) and Prostaglandin E₁ (PGE₁) have been used effectively as single agents to ameliorate renal ischemia-reperfusion injury. We hypothesized that combined treatment with L-arg and PGE₁would be more effective. <i>Materials and Methods:</i> The left renal artery of male Sprague-Dawley rats was clamped for 45 min and the right kidney was removed. Fifty six rats were randomly allocated into 5 groups each consisted of 12 rats except sham group (n = 8). (1) sham, underwent right nephrectomy only; (2) control, untreated ischemic rats; (3) L-arg group, L-arg-treated ischemic rats; (4) PGE₁ group, PGE₁-treated ischemic rats; (5) L-arg+PGE₁ group, ischemic rats treated with both L-arg and PGE₁. Renal function and histology were assessed on days 2 and 7 postoperatively. <i>Results:</i> All rats, except control ones, showed a significant improvement of renal function towards normal on postoperative day 7. Serum creatinine and creatinine clearance were significantly better in L-arg+PGE₁ group compared to all other groups on day 7. With the exception of sham-operated and L-arg+PGE₁-treated animals, all other groups showed significant increases in fractional excretion of sodium (FE_Na) in response to renal ischemia-reperfusion. The severest tubular damage was determined in the kidneys of control rats. Rats treated with L-arg+PGE₁ had the least severe tubular damage. <i>Conclusion:</i> The administration of either L-arg or PGE₁ attenuates both functional and structural consequences of renal warm ischemia. A near total protection might be achieved when both agents are administered concomitantly." @default.
• W2010425523 created "2016-06-24" @default.
• W2010425523 creator A5033980475 @default.
• W2010425523 creator A5063109886 @default.
• W2010425523 creator A5073498890 @default.
• W2010425523 creator A5082475482 @default.
• W2010425523 creator A5085373071 @default.
• W2010425523 date "2007-03-01" @default.
• W2010425523 modified "2023-09-26" @default.
• W2010425523 title "Role of Combined L-Arginine and Prostaglandin E₁ in Renal Ischemia-Reperfusion Injury" @default.
• W2010425523 cites W1964979213 @default.
• W2010425523 cites W1967729440 @default.
• W2010425523 cites W1975896607 @default.
• W2010425523 cites W1986429878 @default.
• W2010425523 cites W1986527465 @default.
• W2010425523 cites W1997223195 @default.
• W2010425523 cites W2004770285 @default.
• W2010425523 cites W2007354513 @default.
• W2010425523 cites W2011307569 @default.
• W2010425523 cites W2016040130 @default.
• W2010425523 cites W2021403302 @default.
• W2010425523 cites W2026371035 @default.
• W2010425523 cites W2029491963 @default.
• W2010425523 cites W2035401506 @default.
• W2010425523 cites W2038297645 @default.
• W2010425523 cites W2039199937 @default.
• W2010425523 cites W2040030129 @default.
• W2010425523 cites W2044418405 @default.
• W2010425523 cites W2046622912 @default.
• W2010425523 cites W2065842089 @default.
• W2010425523 cites W2066153805 @default.
• W2010425523 cites W2071367062 @default.
• W2010425523 cites W2077249375 @default.
• W2010425523 cites W2078556415 @default.
• W2010425523 cites W2089747387 @default.
• W2010425523 cites W2090890003 @default.
• W2010425523 cites W2092856484 @default.
• W2010425523 cites W2118863177 @default.
• W2010425523 cites W2131868847 @default.
• W2010425523 cites W2139529386 @default.
• W2010425523 cites W2156578117 @default.
• W2010425523 cites W4234071946 @default.
• W2010425523 cites W4243698721 @default.
• W2010425523 doi "https://doi.org/10.1159/000100425" @default.
• W2010425523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17337910" @default.
• W2010425523 hasPublicationYear "2007" @default.
• W2010425523 type Work @default.
• W2010425523 sameAs 2010425523 @default.
• W2010425523 citedByCount "11" @default.
• W2010425523 countsByYear W20104255232012 @default.
• W2010425523 countsByYear W20104255232013 @default.
• W2010425523 countsByYear W20104255232016 @default.
• W2010425523 countsByYear W20104255232018 @default.
• W2010425523 countsByYear W20104255232020 @default.
• W2010425523 countsByYear W20104255232022 @default.
• W2010425523 crossrefType "journal-article" @default.
• W2010425523 hasAuthorship W2010425523A5033980475 @default.
• W2010425523 hasAuthorship W2010425523A5063109886 @default.
• W2010425523 hasAuthorship W2010425523A5073498890 @default.
• W2010425523 hasAuthorship W2010425523A5082475482 @default.
• W2010425523 hasAuthorship W2010425523A5085373071 @default.
• W2010425523 hasConcept C126322002 @default.
• W2010425523 hasConcept C134018914 @default.
• W2010425523 hasConcept C159641895 @default.
• W2010425523 hasConcept C2777198256 @default.
• W2010425523 hasConcept C2779311647 @default.
• W2010425523 hasConcept C2780091579 @default.
• W2010425523 hasConcept C2780114680 @default.
• W2010425523 hasConcept C2780227381 @default.
• W2010425523 hasConcept C2780306776 @default.
• W2010425523 hasConcept C2780664492 @default.
• W2010425523 hasConcept C2780721119 @default.
• W2010425523 hasConcept C541997718 @default.
• W2010425523 hasConcept C71924100 @default.
• W2010425523 hasConceptScore W2010425523C126322002 @default.
• W2010425523 hasConceptScore W2010425523C134018914 @default.
• W2010425523 hasConceptScore W2010425523C159641895 @default.
• W2010425523 hasConceptScore W2010425523C2777198256 @default.
• W2010425523 hasConceptScore W2010425523C2779311647 @default.
• W2010425523 hasConceptScore W2010425523C2780091579 @default.
• W2010425523 hasConceptScore W2010425523C2780114680 @default.
• W2010425523 hasConceptScore W2010425523C2780227381 @default.
• W2010425523 hasConceptScore W2010425523C2780306776 @default.
• W2010425523 hasConceptScore W2010425523C2780664492 @default.
• W2010425523 hasConceptScore W2010425523C2780721119 @default.
• W2010425523 hasConceptScore W2010425523C541997718 @default.
• W2010425523 hasConceptScore W2010425523C71924100 @default.
• W2010425523 hasIssue "4" @default.
• W2010425523 hasLocation W20104255231 @default.
• W2010425523 hasLocation W20104255232 @default.
• W2010425523 hasOpenAccess W2010425523 @default.
• W2010425523 hasPrimaryLocation W20104255231 @default.
• W2010425523 hasRelatedWork W1490312285 @default.
• W2010425523 hasRelatedWork W2009617568 @default.
• W2010425523 hasRelatedWork W2016815653 @default.
• W2010425523 hasRelatedWork W2062439275 @default.
• W2010425523 hasRelatedWork W2084442026 @default.
• W2010425523 hasRelatedWork W2115814773 @default.

• next