Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010434645> ?p ?o ?g. }
- W2010434645 endingPage "e992217" @default.
- W2010434645 startingPage "e992217" @default.
- W2010434645 abstract "Metabolomics has emerged as a new discovery tool with the promise of identifying therapeutic targets in cancer. Recent discoveries described essential metabolomic pathways in breast cancer and characterized oncometabolites that drive tumor growth and progression. Oncogenes like MYC and tumor suppressor genes like TP53 prominently affect breast cancer biology through regulation of cell metabolism and mitochondrial biogenesis. These findings indicate that tumors with dominant mutations could be susceptible to inhibitors of disease metabolism. Moreover, various pre-clinical and clinical studies have linked tumor metabolism to therapeutic response and patient survival. Thus, recent advances suggest that metabolic profiling provides new opportunities to improve outcomes in breast cancer. In this review, we have summarized some of the identified roles of oncometabolites in breast cancer biology and highlight their clinical utility." @default.
- W2010434645 created "2016-06-24" @default.
- W2010434645 creator A5027170042 @default.
- W2010434645 creator A5080471399 @default.
- W2010434645 date "2015-01-07" @default.
- W2010434645 modified "2023-10-18" @default.
- W2010434645 title "Metabolic signatures of human breast cancer" @default.
- W2010434645 cites W1486422396 @default.
- W2010434645 cites W1640494480 @default.
- W2010434645 cites W1896429920 @default.
- W2010434645 cites W1963582543 @default.
- W2010434645 cites W1964480573 @default.
- W2010434645 cites W1964891521 @default.
- W2010434645 cites W1964959571 @default.
- W2010434645 cites W1974032653 @default.
- W2010434645 cites W1975215468 @default.
- W2010434645 cites W1977622464 @default.
- W2010434645 cites W1980181091 @default.
- W2010434645 cites W1982330633 @default.
- W2010434645 cites W1983079076 @default.
- W2010434645 cites W1984621921 @default.
- W2010434645 cites W1989568128 @default.
- W2010434645 cites W1990542495 @default.
- W2010434645 cites W1991394829 @default.
- W2010434645 cites W1995321444 @default.
- W2010434645 cites W1998142996 @default.
- W2010434645 cites W1999599951 @default.
- W2010434645 cites W2004045970 @default.
- W2010434645 cites W2009569524 @default.
- W2010434645 cites W2013747211 @default.
- W2010434645 cites W2014988241 @default.
- W2010434645 cites W2015207840 @default.
- W2010434645 cites W2016535776 @default.
- W2010434645 cites W2022369905 @default.
- W2010434645 cites W2022899908 @default.
- W2010434645 cites W2023947368 @default.
- W2010434645 cites W2024367581 @default.
- W2010434645 cites W2025342576 @default.
- W2010434645 cites W2034530633 @default.
- W2010434645 cites W2036192035 @default.
- W2010434645 cites W2036536263 @default.
- W2010434645 cites W2038009564 @default.
- W2010434645 cites W2039343804 @default.
- W2010434645 cites W2039558597 @default.
- W2010434645 cites W2044055595 @default.
- W2010434645 cites W2044702943 @default.
- W2010434645 cites W2046584993 @default.
- W2010434645 cites W2048540822 @default.
- W2010434645 cites W2050377304 @default.
- W2010434645 cites W2056174640 @default.
- W2010434645 cites W2056648518 @default.
- W2010434645 cites W2062515127 @default.
- W2010434645 cites W2066411725 @default.
- W2010434645 cites W2070432942 @default.
- W2010434645 cites W2072816950 @default.
- W2010434645 cites W2075394689 @default.
- W2010434645 cites W2078358665 @default.
- W2010434645 cites W2078972833 @default.
- W2010434645 cites W2080452140 @default.
- W2010434645 cites W2082318061 @default.
- W2010434645 cites W2086816631 @default.
- W2010434645 cites W2089041399 @default.
- W2010434645 cites W2096283457 @default.
- W2010434645 cites W2096410299 @default.
- W2010434645 cites W2097255042 @default.
- W2010434645 cites W2097259163 @default.
- W2010434645 cites W2099335989 @default.
- W2010434645 cites W2099660203 @default.
- W2010434645 cites W2101239722 @default.
- W2010434645 cites W2104542806 @default.
- W2010434645 cites W2106393230 @default.
- W2010434645 cites W2108195113 @default.
- W2010434645 cites W2108560895 @default.
- W2010434645 cites W2110521199 @default.
- W2010434645 cites W2112106342 @default.
- W2010434645 cites W2116465095 @default.
- W2010434645 cites W2117594441 @default.
- W2010434645 cites W2119239003 @default.
- W2010434645 cites W2120553786 @default.
- W2010434645 cites W2121630405 @default.
- W2010434645 cites W2121727754 @default.
- W2010434645 cites W2124966133 @default.
- W2010434645 cites W2126524529 @default.
- W2010434645 cites W2127624416 @default.
- W2010434645 cites W2131719921 @default.
- W2010434645 cites W2131860315 @default.
- W2010434645 cites W2131994307 @default.
- W2010434645 cites W2132053398 @default.
- W2010434645 cites W2132117833 @default.
- W2010434645 cites W2132151783 @default.
- W2010434645 cites W2140472853 @default.
- W2010434645 cites W2141627190 @default.
- W2010434645 cites W2142084063 @default.
- W2010434645 cites W2142765712 @default.
- W2010434645 cites W2143044700 @default.
- W2010434645 cites W2144957807 @default.
- W2010434645 cites W2145742835 @default.
- W2010434645 cites W2147944526 @default.