Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010473154> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2010473154 endingPage "127" @default.
- W2010473154 startingPage "120" @default.
- W2010473154 abstract "Rapidly progressive periodontitis (RPP) has been suggested as a distinct clinical entity within the spectrum of early onset periodontitis. Immunological mechanisms have been considered in the pathogenesis of RPP. This study was designed to evaluate the distribution and phenotypic properties of the lymphocyte populations within the affected gingival tissue of patients with RPP. Biopsies were obtained from 16 patients between 22 and 33 years of age. The tissue samples were processed for both histopathological and immunohistochemical examinations. Gingival tissue T lymphocytes (CD3+), helper T cells (CD4+), suppressor-cytotoxic T cells (CD8+), and cells positive for HLA-DR antigen were identified using monoclonal antibodies with an immunoperoxidase technique. Intracytoplasmic immunoglobulin-containing cells were also stained immunohistochemically with polyclonal antibodies. CD3+ cells were mainly located beneath the pocket epithelium. CD4+ and CD8+ cells were evenly distributed within this T-cell infiltrate with a CD4+/CD8+ ratio of 1:12. Numerous HLA-DR+ cells were also observed in the lymphocytic infiltrates. The majority of mononuclear cells located throughout the stroma were IgG+ plasma cells. Our results indicate that RPP patients present an IgG-bearing plasma cell dominated lesion with equal participation of both T-cell subpopulations. These findings suggest that activation and proliferation of B-cells play an important role in the pathogenesis of periodontal diseases." @default.
- W2010473154 created "2016-06-24" @default.
- W2010473154 creator A5017723996 @default.
- W2010473154 creator A5020197899 @default.
- W2010473154 creator A5029610866 @default.
- W2010473154 creator A5044850502 @default.
- W2010473154 creator A5081405141 @default.
- W2010473154 date "1993-02-01" @default.
- W2010473154 modified "2023-10-18" @default.
- W2010473154 title "<i>In Situ</i> Characterization of Gingival Mononuclear Cells in Rapidly Progressive Periodontitis" @default.
- W2010473154 cites W1510298326 @default.
- W2010473154 cites W1911962423 @default.
- W2010473154 cites W1971890827 @default.
- W2010473154 cites W1975129133 @default.
- W2010473154 cites W1995597174 @default.
- W2010473154 cites W1997386790 @default.
- W2010473154 cites W2006987999 @default.
- W2010473154 cites W2016210266 @default.
- W2010473154 cites W2021792184 @default.
- W2010473154 cites W2031249923 @default.
- W2010473154 cites W2033936252 @default.
- W2010473154 cites W2043759777 @default.
- W2010473154 cites W2062702817 @default.
- W2010473154 cites W2126798482 @default.
- W2010473154 cites W2132614349 @default.
- W2010473154 doi "https://doi.org/10.1902/jop.1993.64.2.120" @default.
- W2010473154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8433251" @default.
- W2010473154 hasPublicationYear "1993" @default.
- W2010473154 type Work @default.
- W2010473154 sameAs 2010473154 @default.
- W2010473154 citedByCount "23" @default.
- W2010473154 countsByYear W20104731542012 @default.
- W2010473154 countsByYear W20104731542013 @default.
- W2010473154 countsByYear W20104731542015 @default.
- W2010473154 countsByYear W20104731542016 @default.
- W2010473154 crossrefType "journal-article" @default.
- W2010473154 hasAuthorship W2010473154A5017723996 @default.
- W2010473154 hasAuthorship W2010473154A5020197899 @default.
- W2010473154 hasAuthorship W2010473154A5029610866 @default.
- W2010473154 hasAuthorship W2010473154A5044850502 @default.
- W2010473154 hasAuthorship W2010473154A5081405141 @default.
- W2010473154 hasConcept C114684123 @default.
- W2010473154 hasConcept C126322002 @default.
- W2010473154 hasConcept C128102431 @default.
- W2010473154 hasConcept C137061746 @default.
- W2010473154 hasConcept C142724271 @default.
- W2010473154 hasConcept C147483822 @default.
- W2010473154 hasConcept C154317977 @default.
- W2010473154 hasConcept C159654299 @default.
- W2010473154 hasConcept C167672396 @default.
- W2010473154 hasConcept C202751555 @default.
- W2010473154 hasConcept C203014093 @default.
- W2010473154 hasConcept C2780385504 @default.
- W2010473154 hasConcept C2780942790 @default.
- W2010473154 hasConcept C542903549 @default.
- W2010473154 hasConcept C55493867 @default.
- W2010473154 hasConcept C71924100 @default.
- W2010473154 hasConcept C86803240 @default.
- W2010473154 hasConceptScore W2010473154C114684123 @default.
- W2010473154 hasConceptScore W2010473154C126322002 @default.
- W2010473154 hasConceptScore W2010473154C128102431 @default.
- W2010473154 hasConceptScore W2010473154C137061746 @default.
- W2010473154 hasConceptScore W2010473154C142724271 @default.
- W2010473154 hasConceptScore W2010473154C147483822 @default.
- W2010473154 hasConceptScore W2010473154C154317977 @default.
- W2010473154 hasConceptScore W2010473154C159654299 @default.
- W2010473154 hasConceptScore W2010473154C167672396 @default.
- W2010473154 hasConceptScore W2010473154C202751555 @default.
- W2010473154 hasConceptScore W2010473154C203014093 @default.
- W2010473154 hasConceptScore W2010473154C2780385504 @default.
- W2010473154 hasConceptScore W2010473154C2780942790 @default.
- W2010473154 hasConceptScore W2010473154C542903549 @default.
- W2010473154 hasConceptScore W2010473154C55493867 @default.
- W2010473154 hasConceptScore W2010473154C71924100 @default.
- W2010473154 hasConceptScore W2010473154C86803240 @default.
- W2010473154 hasIssue "2" @default.
- W2010473154 hasLocation W20104731541 @default.
- W2010473154 hasLocation W20104731542 @default.
- W2010473154 hasOpenAccess W2010473154 @default.
- W2010473154 hasPrimaryLocation W20104731541 @default.
- W2010473154 hasRelatedWork W1570398970 @default.
- W2010473154 hasRelatedWork W2034871748 @default.
- W2010473154 hasRelatedWork W2044625955 @default.
- W2010473154 hasRelatedWork W2348071268 @default.
- W2010473154 hasRelatedWork W2350566529 @default.
- W2010473154 hasRelatedWork W2359198796 @default.
- W2010473154 hasRelatedWork W2367868627 @default.
- W2010473154 hasRelatedWork W2384437467 @default.
- W2010473154 hasRelatedWork W2393732435 @default.
- W2010473154 hasRelatedWork W2403582269 @default.
- W2010473154 hasVolume "64" @default.
- W2010473154 isParatext "false" @default.
- W2010473154 isRetracted "false" @default.
- W2010473154 magId "2010473154" @default.
- W2010473154 workType "article" @default.