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- W2010476811 abstract "Abstract The major polyprotein precursors of the four internal structural proteins of Rauscher murine leukemia virus, designated p30, p15, p12, and p10 (collectively termed “gag” proteins), have been characterized. Tryptic peptide sequences and antigenic determinants of the gag proteins are contained in precursor polyproteins Pr3 (≅80,000) and Pr4 (≅65,000 daltons). Two minor precursor polyproteins have also been identified and partially characterized. They are designated Pr5 (≅55,000) and Pr6 (≅45,000 daltons). Pr5 contains peptide sequences of p30, p15, and p12; Pr6 contains sequences of p30 and p12 but lacks p15 sequences. The presence or absence of p10 sequences in Pr5 and Pr6 remains to be established. The major pathway for formation of the gag proteins appears to be via synthesis and processing of Pr3. Antigenic determinants of the gag proteins (and p30 peptide sequences) are also contained in a polyprotein precursor termed Prl a +b (molecular weight, ≅200,000). The latter has also been shown to share antigenic determinants with the reverse transcriptase [ Jamjoom, G. A., Naso, R. B., and Arlinghaus, R. B. (1977) . Virology 78, 11-341." @default.
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- W2010476811 date "1977-09-01" @default.
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- W2010476811 title "“gag” polyprotein precursors of rauscher murine leukemia virus" @default.
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- W2010476811 doi "https://doi.org/10.1016/0042-6822(77)90145-3" @default.
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