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- W2010501192 abstract "The effect of β-alanine, γ-aminobutyric acid (GABA), and other functionally related amino acids on [3H]flunitrazepam binding to rat spinal cord homogenates was studied. β-Alanine potentiated [3H]flunitrazepam binding by 40% and GABA by 88%. Taurine increased the binding by 19%. Hypotaurine produced an 11% increase. No significant effect was seen in glycine, alanine, serine, valine or the dipeptide carnosine. The β-alanine increase in [3H]flunitrazepam binding was completely inhibited by 10 μM strychnine, where-as the GABA increase required 0.1 mM strychnine to be fully suppressed. Results suggest that β-alanine specifically potentiates binding of [3H]flunitrazepam in rat spinal cord homogenates." @default.
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- W2010501192 date "1990-04-01" @default.
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- W2010501192 title "β-Alanine potentiation of [3H]flunitrazepam binding to rat spinal cord homogenates" @default.
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- W2010501192 doi "https://doi.org/10.1016/0304-3940(90)90268-e" @default.
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