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- W2010503586 abstract "In addition to age, gender, family history, hypertension, smoking, and diabetes, significant risk factors for coronary heart disease (CHD) in the Framingham Heart Study include an elevated plasma level of low-density lipoprotein (LDL) cholesterol (>160 mg/dl or 4.1 mmol/l), an elevated lipoprotein (a) (Lp[a]) cholesterol (≥10 mg/dl or 0.25 mmol/l), an elevated lipoprotein remnant-like lipoprotein particle (RLP) cholesterol (>10 mg/dl or 0.25 mmol/l), and a decreased high-density lipoprotein (HDL) cholesterol (<35 mg/dl or 0.9 mmol/l) (Circulation 97: 1837–1845, 1998). Direct assays for the measurement of these consituents in serum or plasma are now available (Clin Chem 40: 400–403, 1994; 41: 232–240, 1995; 44: 1224–1232, 1998). In the Framingham Heart Study the most important factors regulating HDL cholesterol levels are gender, triglyceride levels, alcohol intake, body mass index, and cigarette smoking (J Lipid Res 35: 871–882; 1994). Other significant independent CHD risk factors include elevated fibrinogen and homocysteine levels." @default.
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- W2010503586 date "1999-09-01" @default.
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- W2010503586 title "3. High-density lipoprotein as a coronary heart disease risk factor and gene mutations affecting high-density lipoprotein cholesterol levels: results from the Framingham Heart Study" @default.
- W2010503586 doi "https://doi.org/10.1016/s0021-9150(99)00225-7" @default.
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