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- W2010538897 abstract "The rate of progression of cycling HeLa cells from G2 into mitosis is greatly reduced by the amino acid analogue, p-fluorophenylalanine, but a small percentage of cells continually escapes into mitosis. Most of a presynchronized population can be held for several h in G2, thereby facilitating analyses of cells at this late stage of the cell cycle. They are reversed from the block by the addition of phenylalanine and resume progression within about 1 h with predictable kinetics but without a significantly enhanced synchrony. The mechanism of action of the analogue is consistent with the hypothesis that synthesis of false proteins interferes with the correct assembly of division-relevant structures." @default.
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- W2010538897 date "1979-12-01" @default.
- W2010538897 modified "2023-09-24" @default.
- W2010538897 title "Reversible retention of synchronized HeLa cells in G of the mammalian cell cycle" @default.
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- W2010538897 doi "https://doi.org/10.1016/0309-1651(79)90079-1" @default.
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