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• W2010558368 startingPage "538" @default.
• W2010558368 abstract "The efficacy of melatonin or its derivatives in depressive patients has been recently considered for clinical application. However, the evidence for its effect on experimental models of depression is not consolidated. Here, the effects of melatonin on the model of forced swim test (FST) paradigm were studied in male rats of the Wistar strain after acute intraperitoneal (i.p.) administration of 0.1, 0.5 or 1 mg/kg of the hormone. Melatonin at doses of 0.5 and 1 mg/kg, but not of 0.1 mg/kg, decreased the immobility of rats in the FST paradigm suggesting a possible antidepressant-like activity. The dose of 0.5 mg/kg appeared to be as potent as clomipramine 50 mg/kg in reducing the immobility time of rats in the FST paradigm. The effect of melatonin on immobility time of rats in the FST paradigm was abolished by the simultaneous injection of the non-selective melatonin antagonist, luzindole (0.25 mg/kg, subcutaneously). Similarly, administration of small quantities of serotonin (5-HT, 5 ng/1 microl) or of the 5-HT(2A)/5-HT(2C) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (2 ng/1 microl) injected into the amygdale totally suppressed the reduction of immobility time in the FST paradigm induced by melatonin 0.5 mg/kg. These results may suggest that effects of melatonin on the behavioral reaction of rats in the FST paradigm are due to an interaction of the hormone with central 5-HT neurotransmission." @default.
• W2010558368 created "2016-06-24" @default.
• W2010558368 creator A5019482800 @default.
• W2010558368 creator A5023326565 @default.
• W2010558368 creator A5070195593 @default.
• W2010558368 creator A5074416657 @default.
• W2010558368 date "2006-10-01" @default.
• W2010558368 modified "2023-09-26" @default.
• W2010558368 title "Melatonin affects the immobility time of rats in the forced swim test: The role of serotonin neurotransmission" @default.
• W2010558368 cites W144931552 @default.
• W2010558368 cites W1491332053 @default.
• W2010558368 cites W1560550807 @default.
• W2010558368 cites W1965543679 @default.
• W2010558368 cites W1965677206 @default.
• W2010558368 cites W1972107530 @default.
• W2010558368 cites W1973386992 @default.
• W2010558368 cites W1973400965 @default.
• W2010558368 cites W1977708183 @default.
• W2010558368 cites W1978477157 @default.
• W2010558368 cites W1978654570 @default.
• W2010558368 cites W1981138864 @default.
• W2010558368 cites W1985143235 @default.
• W2010558368 cites W1988468531 @default.
• W2010558368 cites W1989675945 @default.
• W2010558368 cites W1990507462 @default.
• W2010558368 cites W1995441711 @default.
• W2010558368 cites W1997899627 @default.
• W2010558368 cites W2001823526 @default.
• W2010558368 cites W2002224654 @default.
• W2010558368 cites W2003201823 @default.
• W2010558368 cites W2003545653 @default.
• W2010558368 cites W2004118951 @default.
• W2010558368 cites W2005578700 @default.
• W2010558368 cites W2006586494 @default.
• W2010558368 cites W2014182497 @default.
• W2010558368 cites W2016351175 @default.
• W2010558368 cites W2022032351 @default.
• W2010558368 cites W2023928627 @default.
• W2010558368 cites W2024240021 @default.
• W2010558368 cites W2024739259 @default.
• W2010558368 cites W2025678690 @default.
• W2010558368 cites W2027842287 @default.
• W2010558368 cites W2028039861 @default.
• W2010558368 cites W2035121631 @default.
• W2010558368 cites W2037831322 @default.
• W2010558368 cites W2039744210 @default.
• W2010558368 cites W2041076472 @default.
• W2010558368 cites W2041263807 @default.
• W2010558368 cites W2044821770 @default.
• W2010558368 cites W2045282219 @default.
• W2010558368 cites W2045644996 @default.
• W2010558368 cites W2046570460 @default.
• W2010558368 cites W2048631090 @default.
• W2010558368 cites W2057200138 @default.
• W2010558368 cites W2059114228 @default.
• W2010558368 cites W2059660519 @default.
• W2010558368 cites W2061933392 @default.
• W2010558368 cites W2063085120 @default.
• W2010558368 cites W2063618622 @default.
• W2010558368 cites W2063787166 @default.
• W2010558368 cites W2068341795 @default.
• W2010558368 cites W2073432994 @default.
• W2010558368 cites W2076120938 @default.
• W2010558368 cites W2083056265 @default.
• W2010558368 cites W2085156548 @default.
• W2010558368 cites W2087093507 @default.
• W2010558368 cites W2087720573 @default.
• W2010558368 cites W2089210700 @default.
• W2010558368 cites W2094052772 @default.
• W2010558368 cites W2119078954 @default.
• W2010558368 cites W2119803867 @default.
• W2010558368 cites W2127872798 @default.
• W2010558368 cites W2130100911 @default.
• W2010558368 cites W2131167630 @default.
• W2010558368 cites W2136350449 @default.
• W2010558368 cites W2144665117 @default.
• W2010558368 cites W2157539184 @default.
• W2010558368 cites W2302121233 @default.
• W2010558368 cites W2324480980 @default.
• W2010558368 cites W2416939370 @default.
• W2010558368 cites W967356148 @default.
• W2010558368 cites W2005246163 @default.
• W2010558368 doi "https://doi.org/10.1016/j.euroneuro.2006.01.005" @default.
• W2010558368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16527463" @default.
• W2010558368 hasPublicationYear "2006" @default.
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