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- W2010589551 abstract "Antibodies to Pneumocystis carinii develop in early childhood,1 although no associated illness has been identified. The classic concept in that P carinii pneumonia in immunocompromised patients represents a reactivation of dormant childhood infection. Studies with DNA amplification, however, have failed to detect pneumocystis in sputum2 or specimens of lung tissue taken at necropsy3 from immunocompetent patients. Reinfection rather than reactivation may therefore be more relevant. To see whether P carinii exists as a commensal organism of the lower respiratory tract we examined bronchoalveolar lavage fluid and bronchial washings in apparently immunocompetent patients undergoing routine diagnostic (or research) bronchoscopy by using an immunofluorescent antibody test.We studied 220 patients with various clinical diagnoses (table). Patients were considered to have no active disease if investigations, including bronchoscopy, failed to show any lung disease. Patients with …" @default.
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- W2010589551 date "1994-05-07" @default.
- W2010589551 modified "2023-09-25" @default.
- W2010589551 title "Pneumocystis carinii in bronchoalveolar lavage fluid and bronchial washings" @default.
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- W2010589551 doi "https://doi.org/10.1136/bmj.308.6938.1206" @default.
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