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• W2010595715 endingPage "21" @default.
• W2010595715 startingPage "1" @default.
• W2010595715 abstract "Memory cells, the ultimate neurobiological substrates of working memory, remain active for several seconds and are most commonly found in prefrontal cortex and higher multisensory areas. However, if correlated activity in “embodied” sensorimotor systems underlies the formation of memory traces, why should memory cells emerge in areas distant from their antecedent activations in sensorimotor areas, thus leading to “disembodiment” (movement away from sensorimotor systems) of memory mechanisms? We modelled the formation of memory circuits in six-area neurocomputational architectures, implementing motor and sensory primary, secondary and higher association areas in frontotemporal cortices along with known between-area neuroanatomical connections. Sensorimotor learning driven by Hebbian neuroplasticity led to formation of cell assemblies distributed across the different areas of the network. These action-perception circuits (APCs) ignited fully when stimulated, thus providing a neural basis for long-term memory (LTM) of sensorimotor information linked by learning. Subsequent to ignition, activity vanished rapidly from APC neurons in sensorimotor areas but persisted in those in multimodal prefrontal and temporal areas. Such persistent activity provides a mechanism for working memory for actions, perceptions and symbols, including short-term phonological and semantic storage. Cell assembly ignition and “disembodied” working memory retreat of activity to multimodal areas are documented in the neurocomputational models' activity dynamics, at the level of single cells, circuits, and cortical areas. Memory disembodiment is explained neuromechanistically by APC formation and structural neuroanatomical features of the model networks, especially the central role of multimodal prefrontal and temporal cortices in bridging between sensory and motor areas. These simulations answer the “where” question of cortical working memory in terms of distributed APCs and their inner structure, which is, in part, determined by neuroanatomical structure. As the neurocomputational model provides a mechanistic explanation of how memory-related “disembodied” neuronal activity emerges in “embodied” APCs, it may be key to solving aspects of the embodiment debate and eventually to a better understanding of cognitive brain functions." @default.
• W2010595715 created "2016-06-24" @default.
• W2010595715 creator A5045983550 @default.
• W2010595715 creator A5052197754 @default.
• W2010595715 date "2014-08-01" @default.
• W2010595715 modified "2023-09-25" @default.
• W2010595715 title "From sensorimotor learning to memory cells in prefrontal and temporal association cortex: A neurocomputational study of disembodiment" @default.
• W2010595715 cites W1480711868 @default.
• W2010595715 cites W1516329115 @default.
• W2010595715 cites W1527855123 @default.
• W2010595715 cites W1577296797 @default.
• W2010595715 cites W1595091917 @default.
• W2010595715 cites W1607957700 @default.
• W2010595715 cites W1645271453 @default.
• W2010595715 cites W1758538055 @default.
• W2010595715 cites W1864836097 @default.
• W2010595715 cites W1901661521 @default.
• W2010595715 cites W1939596644 @default.
• W2010595715 cites W1965735313 @default.
• W2010595715 cites W1968001820 @default.
• W2010595715 cites W1968073393 @default.
• W2010595715 cites W1977187949 @default.
• W2010595715 cites W1977340386 @default.
• W2010595715 cites W1978372223 @default.
• W2010595715 cites W1978668587 @default.
• W2010595715 cites W1985807796 @default.
• W2010595715 cites W1986856036 @default.
• W2010595715 cites W1990270091 @default.
• W2010595715 cites W1990535258 @default.
• W2010595715 cites W1991593445 @default.
• W2010595715 cites W1995735788 @default.
• W2010595715 cites W1996227544 @default.
• W2010595715 cites W1996348120 @default.
• W2010595715 cites W1997026829 @default.
• W2010595715 cites W2001524933 @default.
• W2010595715 cites W2002429803 @default.
• W2010595715 cites W2004547450 @default.
• W2010595715 cites W2004763811 @default.
• W2010595715 cites W2007468564 @default.
• W2010595715 cites W2008459347 @default.
• W2010595715 cites W2010928959 @default.
• W2010595715 cites W2015303758 @default.
• W2010595715 cites W2015543198 @default.
• W2010595715 cites W2019401192 @default.
• W2010595715 cites W2022856253 @default.
• W2010595715 cites W2024151042 @default.
• W2010595715 cites W2024517947 @default.
• W2010595715 cites W2024877072 @default.
• W2010595715 cites W2025192393 @default.
• W2010595715 cites W2029451026 @default.
• W2010595715 cites W2030092281 @default.
• W2010595715 cites W2031534534 @default.
• W2010595715 cites W2032563801 @default.
• W2010595715 cites W2032907274 @default.
• W2010595715 cites W2035649492 @default.
• W2010595715 cites W2035651017 @default.
• W2010595715 cites W2036447011 @default.
• W2010595715 cites W2037990198 @default.
• W2010595715 cites W2038960392 @default.
• W2010595715 cites W2039756648 @default.
• W2010595715 cites W2042328200 @default.
• W2010595715 cites W2044129383 @default.
• W2010595715 cites W2046572522 @default.
• W2010595715 cites W2046813578 @default.
• W2010595715 cites W2049430110 @default.
• W2010595715 cites W2051353051 @default.
• W2010595715 cites W2052493326 @default.
• W2010595715 cites W2053138442 @default.
• W2010595715 cites W2053389780 @default.
• W2010595715 cites W2054119148 @default.
• W2010595715 cites W2056397825 @default.
• W2010595715 cites W2056603317 @default.
• W2010595715 cites W2057529293 @default.
• W2010595715 cites W2058537734 @default.
• W2010595715 cites W2059049804 @default.
• W2010595715 cites W2060449369 @default.
• W2010595715 cites W2061982926 @default.
• W2010595715 cites W2064615902 @default.
• W2010595715 cites W2066543516 @default.
• W2010595715 cites W2066785847 @default.
• W2010595715 cites W2070900790 @default.
• W2010595715 cites W2073090260 @default.
• W2010595715 cites W2073729506 @default.
• W2010595715 cites W2075328753 @default.
• W2010595715 cites W2076748564 @default.
• W2010595715 cites W2077758457 @default.
• W2010595715 cites W2077951358 @default.
• W2010595715 cites W2082928871 @default.
• W2010595715 cites W2087946919 @default.
• W2010595715 cites W2091301585 @default.
• W2010595715 cites W2093072166 @default.
• W2010595715 cites W2098139051 @default.
• W2010595715 cites W2099535060 @default.
• W2010595715 cites W2100675752 @default.
• W2010595715 cites W2103100551 @default.
• W2010595715 cites W2104862635 @default.
• W2010595715 cites W2104926716 @default.
• W2010595715 cites W2109023847 @default.

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