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• W2010598840 abstract "Surface plasmon resonance (SPR) imaging is a powerful technique for high-throughput, real-time, label-free characterization of molecular interactions in a microarray format. In this paper, we demonstrate SPR imaging with nanohole arrays illuminated by a laser source. Periodic nanoholes couple incident photons into SPs, obviating the need for the prism used in conventional SPR instruments, while a laser source provides the intensity, stability and spectral coherence to improve the detection sensitivity. The formation of a self-assembled monolayer of alkanethiolates on gold changed the laser transmission by more than 35%, and binding kinetics were measured in parallel from a 5 x 3 microarray of nanohole sensors. These results demonstrate the potential of nanohole sensors for high-throughput SPR imaging on microarrays." @default.
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• W2010598840 date "2008-01-01" @default.
• W2010598840 modified "2023-10-12" @default.
• W2010598840 title "Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing" @default.
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• W2010598840 doi "https://doi.org/10.1364/oe.16.000219" @default.
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