FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010600977> ?p ?o ?g. }

• W2010600977 endingPage "57" @default.
• W2010600977 startingPage "51" @default.
• W2010600977 abstract "In rat, fipronil treatment increases the elimination of thyroid hormones (TH). Relevance of this mechanism for the risk of fipronil for human health is subject to controversy because of the specificities of adult rat for TH plasma binding properties which often lead to the assumption that rats are more sensitive than human to thyroid disruption. This study aimed at determining if the mechanism of fipronil-induced thyroid disruption is altered in sheep a species more relevant to human from the standpoint of TH plasma binding. TSH, total triiodothyronine and free and total tetra-iodothyronine 24 h secretory profiles were not modified by fipronil treatment (5 mg/kg every 4 days per os) in rams. In euthyroid-like thyroidectomised ewes, the effect of this treatment was limited to a moderate increase in free T4 clearance. In contrast with the rat, fipronil treatment (0.5 mg/kg/day, IV for 14 days) had no effect on antipyrine clearance, a marker for hepatic cytochrome activity, in ewes. The differences between rat and sheep for the potential of fipronil as a thyroid disruptor might be related to the difference in the exposure to the toxicant, the actual exposure to the sulfone metabolite of fipronil being lower in sheep than in rat." @default.
• W2010600977 created "2016-06-24" @default.
• W2010600977 creator A5032572523 @default.
• W2010600977 creator A5066587645 @default.
• W2010600977 creator A5071905177 @default.
• W2010600977 creator A5072254102 @default.
• W2010600977 creator A5079820017 @default.
• W2010600977 date "2010-05-01" @default.
• W2010600977 modified "2023-09-27" @default.
• W2010600977 title "Is the mechanisms of fipronil-induced thyroid disruption specific of the rat: Re-evaluation of fipronil thyroid toxicity in sheep?" @default.
• W2010600977 cites W1517519529 @default.
• W2010600977 cites W1972990997 @default.
• W2010600977 cites W1973047909 @default.
• W2010600977 cites W1986746415 @default.
• W2010600977 cites W1991893610 @default.
• W2010600977 cites W2011130939 @default.
• W2010600977 cites W2011909468 @default.
• W2010600977 cites W2013915034 @default.
• W2010600977 cites W2020242913 @default.
• W2010600977 cites W2021995068 @default.
• W2010600977 cites W2025268569 @default.
• W2010600977 cites W2033593810 @default.
• W2010600977 cites W2044819383 @default.
• W2010600977 cites W2046911789 @default.
• W2010600977 cites W2050262822 @default.
• W2010600977 cites W2063556633 @default.
• W2010600977 cites W2068590394 @default.
• W2010600977 cites W2070337790 @default.
• W2010600977 cites W2073496541 @default.
• W2010600977 cites W2073913340 @default.
• W2010600977 cites W2075156087 @default.
• W2010600977 cites W2086641164 @default.
• W2010600977 cites W2092752086 @default.
• W2010600977 cites W2154341508 @default.
• W2010600977 cites W2158057955 @default.
• W2010600977 cites W2891774351 @default.
• W2010600977 cites W4239840595 @default.
• W2010600977 doi "https://doi.org/10.1016/j.toxlet.2010.01.018" @default.
• W2010600977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20117195" @default.
• W2010600977 hasPublicationYear "2010" @default.
• W2010600977 type Work @default.
• W2010600977 sameAs 2010600977 @default.
• W2010600977 citedByCount "27" @default.
• W2010600977 countsByYear W20106009772012 @default.
• W2010600977 countsByYear W20106009772013 @default.
• W2010600977 countsByYear W20106009772014 @default.
• W2010600977 countsByYear W20106009772015 @default.
• W2010600977 countsByYear W20106009772016 @default.
• W2010600977 countsByYear W20106009772018 @default.
• W2010600977 countsByYear W20106009772019 @default.
• W2010600977 countsByYear W20106009772020 @default.
• W2010600977 countsByYear W20106009772021 @default.
• W2010600977 countsByYear W20106009772022 @default.
• W2010600977 countsByYear W20106009772023 @default.
• W2010600977 crossrefType "journal-article" @default.
• W2010600977 hasAuthorship W2010600977A5032572523 @default.
• W2010600977 hasAuthorship W2010600977A5066587645 @default.
• W2010600977 hasAuthorship W2010600977A5071905177 @default.
• W2010600977 hasAuthorship W2010600977A5072254102 @default.
• W2010600977 hasAuthorship W2010600977A5079820017 @default.
• W2010600977 hasConcept C126322002 @default.
• W2010600977 hasConcept C134018914 @default.
• W2010600977 hasConcept C161176658 @default.
• W2010600977 hasConcept C185592680 @default.
• W2010600977 hasConcept C2777095047 @default.
• W2010600977 hasConcept C2777195454 @default.
• W2010600977 hasConcept C2777477808 @default.
• W2010600977 hasConcept C2778288131 @default.
• W2010600977 hasConcept C2780473477 @default.
• W2010600977 hasConcept C2780862370 @default.
• W2010600977 hasConcept C29730261 @default.
• W2010600977 hasConcept C46699223 @default.
• W2010600977 hasConcept C526584372 @default.
• W2010600977 hasConcept C6557445 @default.
• W2010600977 hasConcept C71315377 @default.
• W2010600977 hasConcept C71924100 @default.
• W2010600977 hasConcept C86803240 @default.
• W2010600977 hasConcept C98274493 @default.
• W2010600977 hasConceptScore W2010600977C126322002 @default.
• W2010600977 hasConceptScore W2010600977C134018914 @default.
• W2010600977 hasConceptScore W2010600977C161176658 @default.
• W2010600977 hasConceptScore W2010600977C185592680 @default.
• W2010600977 hasConceptScore W2010600977C2777095047 @default.
• W2010600977 hasConceptScore W2010600977C2777195454 @default.
• W2010600977 hasConceptScore W2010600977C2777477808 @default.
• W2010600977 hasConceptScore W2010600977C2778288131 @default.
• W2010600977 hasConceptScore W2010600977C2780473477 @default.
• W2010600977 hasConceptScore W2010600977C2780862370 @default.
• W2010600977 hasConceptScore W2010600977C29730261 @default.
• W2010600977 hasConceptScore W2010600977C46699223 @default.
• W2010600977 hasConceptScore W2010600977C526584372 @default.
• W2010600977 hasConceptScore W2010600977C6557445 @default.
• W2010600977 hasConceptScore W2010600977C71315377 @default.
• W2010600977 hasConceptScore W2010600977C71924100 @default.
• W2010600977 hasConceptScore W2010600977C86803240 @default.
• W2010600977 hasConceptScore W2010600977C98274493 @default.
• W2010600977 hasIssue "3" @default.
• W2010600977 hasLocation W20106009771 @default.

• next