Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010620009> ?p ?o ?g. }
- W2010620009 endingPage "506" @default.
- W2010620009 startingPage "498" @default.
- W2010620009 abstract "We propose classifying surfactants with respect to their effect on membrane order, which is derived from the time-resolved fluorescence anisotropy of DPH. This may help in understanding why certain surfactants, including biosurfactants such as antimicrobial lipopeptides and saponins, often show a superior performance to permeabilize and lyse membranes and/or a better suitability for membrane protein solubilization. Micelle-forming surfactants induce curvature stress in membranes that causes disordering and, finally, lysis. Typical detergents such as C(12)EO(8), octyl glucoside, SDS, and lauryl maltoside initiate membrane lysis after reaching a substantial, apparently critical extent of disordering. In contrast, the fungicidal lipopeptides surfactin, fengycin, and iturin from Bacillus subtilis QST713 as well as digitonin, CHAPS, and lysophosphatidylcholine solubilize membranes without substantial, overall disordering. We hypothesize they disrupt the membrane locally due to a spontaneous segregation from the lipid and/or packing defects and refer to them as heterogeneously perturbing. This may account for enhanced activity, selectivity, and mutual synergism of antimicrobial biosurfactants and reduced destabilization of membrane proteins by CHAPS or digitonin. Triton shows the pattern of a segregating surfactant in the presence of cholesterol." @default.
- W2010620009 created "2016-06-24" @default.
- W2010620009 creator A5005405473 @default.
- W2010620009 creator A5034049746 @default.
- W2010620009 creator A5035259466 @default.
- W2010620009 date "2012-02-01" @default.
- W2010620009 modified "2023-10-04" @default.
- W2010620009 title "Classifying Surfactants with Respect to Their Effect on Lipid Membrane Order" @default.
- W2010620009 cites W1971311524 @default.
- W2010620009 cites W1971383947 @default.
- W2010620009 cites W1972995661 @default.
- W2010620009 cites W1973926195 @default.
- W2010620009 cites W1975882538 @default.
- W2010620009 cites W1976065093 @default.
- W2010620009 cites W1978278603 @default.
- W2010620009 cites W1979936344 @default.
- W2010620009 cites W1988680661 @default.
- W2010620009 cites W1989451255 @default.
- W2010620009 cites W1991523898 @default.
- W2010620009 cites W1995861782 @default.
- W2010620009 cites W1998716985 @default.
- W2010620009 cites W1999398264 @default.
- W2010620009 cites W2001030125 @default.
- W2010620009 cites W2007744639 @default.
- W2010620009 cites W2008738738 @default.
- W2010620009 cites W2008931830 @default.
- W2010620009 cites W2012672431 @default.
- W2010620009 cites W2016189356 @default.
- W2010620009 cites W2016547038 @default.
- W2010620009 cites W2016941835 @default.
- W2010620009 cites W2017814330 @default.
- W2010620009 cites W2027645500 @default.
- W2010620009 cites W2031909431 @default.
- W2010620009 cites W2041173490 @default.
- W2010620009 cites W2046704370 @default.
- W2010620009 cites W2047662477 @default.
- W2010620009 cites W2051263171 @default.
- W2010620009 cites W2052024604 @default.
- W2010620009 cites W2062312846 @default.
- W2010620009 cites W2068067779 @default.
- W2010620009 cites W2071189581 @default.
- W2010620009 cites W2079031526 @default.
- W2010620009 cites W2082111171 @default.
- W2010620009 cites W2091907000 @default.
- W2010620009 cites W2092369371 @default.
- W2010620009 cites W2099848809 @default.
- W2010620009 cites W2101223910 @default.
- W2010620009 cites W2103128020 @default.
- W2010620009 cites W2110814172 @default.
- W2010620009 cites W2128768386 @default.
- W2010620009 cites W2162518738 @default.
- W2010620009 cites W2164054164 @default.
- W2010620009 cites W2165148465 @default.
- W2010620009 cites W2168999294 @default.
- W2010620009 doi "https://doi.org/10.1016/j.bpj.2011.12.029" @default.
- W2010620009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3274831" @default.
- W2010620009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22325272" @default.
- W2010620009 hasPublicationYear "2012" @default.
- W2010620009 type Work @default.
- W2010620009 sameAs 2010620009 @default.
- W2010620009 citedByCount "135" @default.
- W2010620009 countsByYear W20106200092012 @default.
- W2010620009 countsByYear W20106200092013 @default.
- W2010620009 countsByYear W20106200092014 @default.
- W2010620009 countsByYear W20106200092015 @default.
- W2010620009 countsByYear W20106200092016 @default.
- W2010620009 countsByYear W20106200092017 @default.
- W2010620009 countsByYear W20106200092018 @default.
- W2010620009 countsByYear W20106200092019 @default.
- W2010620009 countsByYear W20106200092020 @default.
- W2010620009 countsByYear W20106200092021 @default.
- W2010620009 countsByYear W20106200092022 @default.
- W2010620009 countsByYear W20106200092023 @default.
- W2010620009 crossrefType "journal-article" @default.
- W2010620009 hasAuthorship W2010620009A5005405473 @default.
- W2010620009 hasAuthorship W2010620009A5034049746 @default.
- W2010620009 hasAuthorship W2010620009A5035259466 @default.
- W2010620009 hasBestOaLocation W20106200091 @default.
- W2010620009 hasConcept C11268172 @default.
- W2010620009 hasConcept C122398194 @default.
- W2010620009 hasConcept C12554922 @default.
- W2010620009 hasConcept C178790620 @default.
- W2010620009 hasConcept C184651966 @default.
- W2010620009 hasConcept C185592680 @default.
- W2010620009 hasConcept C2776102837 @default.
- W2010620009 hasConcept C2776330855 @default.
- W2010620009 hasConcept C2777272437 @default.
- W2010620009 hasConcept C2778336440 @default.
- W2010620009 hasConcept C2778596009 @default.
- W2010620009 hasConcept C2778918659 @default.
- W2010620009 hasConcept C2778920010 @default.
- W2010620009 hasConcept C2778987810 @default.
- W2010620009 hasConcept C39944091 @default.
- W2010620009 hasConcept C41625074 @default.
- W2010620009 hasConcept C43617362 @default.
- W2010620009 hasConcept C523546767 @default.
- W2010620009 hasConcept C54355233 @default.
- W2010620009 hasConcept C55493867 @default.