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- W2010626577 abstract "Double deprotonation of α-ketoamides generates dienediolates, which undergo regioselective α-alkylation to yield α-substituted-α-hydroxy-β,γ-unsaturated amides. 1,2-Disubstituted alkenes are generated exclusively as the E-isomer. 1,1-Disubstituted and 1,1,2-trisubstituted olefins can also be prepared. The amides can be readily converted to the corresponding acids." @default.
- W2010626577 created "2016-06-24" @default.
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- W2010626577 date "2006-04-18" @default.
- W2010626577 modified "2023-09-23" @default.
- W2010626577 title "Efficient Synthesis of Quaternary α-Hydroxy Acids by Alkylation of α-Ketoamide-Derived Dienediolates." @default.
- W2010626577 doi "https://doi.org/10.1002/chin.200616089" @default.
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