FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010633605> ?p ?o ?g. }

• W2010633605 endingPage "529" @default.
• W2010633605 startingPage "523" @default.
• W2010633605 abstract "Purpose of review Animal experiments demonstrating associations between birth weight and postnatal phenotypes that may increase the risk of cardiovascular disease, such as hypertension, obesity, anxiety, and increased glucocorticoid activity, support the human epidemiologic findings of an association between reduced size at birth and adult cardiovascular disease. Here we review the evidence for exposure of the fetus to excess glucocorticoid as the key underlying mechanism. Recent findings Administration of synthetic glucocorticoids to, and undernutrition of, pregnant animals both results in reduced birth weight and the relevant postnatal phenotypes. However, in the latter paradigm direct evidence of fetal exposure to excess endogenous glucocorticoids of often lacking. Thirty-year-old offspring of pregnant women given glucocorticoids for threatened preterm labour have minimal evidence of increased cardiovascular risk factors. Summary Exposure of the fetus to inappropriate amounts of glucocorticoids can result in a postnatal phenotype that may predispose to cardiovascular disease, although the fact that surrogate endpoints are often studied in animal experiments must be borne in mind. However, assumptions that effects of other interventions, such as maternal undernutrition, are mediated via exposure of the fetus to excess glucocorticoids are often not supported by direct evidence. The value of available human data should not be overlooked." @default.
• W2010633605 created "2016-06-24" @default.
• W2010633605 creator A5023252382 @default.
• W2010633605 creator A5077353164 @default.
• W2010633605 date "2006-12-01" @default.
• W2010633605 modified "2023-09-26" @default.
• W2010633605 title "Evidence for fetal glucocorticoid excess as a cause of adult cardiovascular disease" @default.
• W2010633605 cites W1549364582 @default.
• W2010633605 cites W1582906291 @default.
• W2010633605 cites W1633496227 @default.
• W2010633605 cites W1926927811 @default.
• W2010633605 cites W1932533342 @default.
• W2010633605 cites W1952521210 @default.
• W2010633605 cites W1971172689 @default.
• W2010633605 cites W1971789895 @default.
• W2010633605 cites W1972426879 @default.
• W2010633605 cites W1978450788 @default.
• W2010633605 cites W1981632099 @default.
• W2010633605 cites W1985891842 @default.
• W2010633605 cites W1986965538 @default.
• W2010633605 cites W1990659922 @default.
• W2010633605 cites W1992752376 @default.
• W2010633605 cites W1996356112 @default.
• W2010633605 cites W2002705855 @default.
• W2010633605 cites W2005271716 @default.
• W2010633605 cites W2014603387 @default.
• W2010633605 cites W2015007412 @default.
• W2010633605 cites W2020469940 @default.
• W2010633605 cites W2029380451 @default.
• W2010633605 cites W2029810456 @default.
• W2010633605 cites W2033327825 @default.
• W2010633605 cites W2035621847 @default.
• W2010633605 cites W2040577292 @default.
• W2010633605 cites W2040814903 @default.
• W2010633605 cites W2041013321 @default.
• W2010633605 cites W2041277193 @default.
• W2010633605 cites W2047372093 @default.
• W2010633605 cites W2052280942 @default.
• W2010633605 cites W2063231989 @default.
• W2010633605 cites W2075312998 @default.
• W2010633605 cites W2081350178 @default.
• W2010633605 cites W2090134829 @default.
• W2010633605 cites W2090583597 @default.
• W2010633605 cites W2096859241 @default.
• W2010633605 cites W2098972044 @default.
• W2010633605 cites W2101863401 @default.
• W2010633605 cites W2106666956 @default.
• W2010633605 cites W2108021565 @default.
• W2010633605 cites W2111793219 @default.
• W2010633605 cites W2112526870 @default.
• W2010633605 cites W2117629615 @default.
• W2010633605 cites W2120771685 @default.
• W2010633605 cites W2121411996 @default.
• W2010633605 cites W2126712716 @default.
• W2010633605 cites W2131165622 @default.
• W2010633605 cites W2133167114 @default.
• W2010633605 cites W2134026632 @default.
• W2010633605 cites W2137542514 @default.
• W2010633605 cites W2139708811 @default.
• W2010633605 cites W2140024762 @default.
• W2010633605 cites W2149135657 @default.
• W2010633605 cites W2155160217 @default.
• W2010633605 cites W2164309494 @default.
• W2010633605 cites W2164872379 @default.
• W2010633605 cites W2168298892 @default.
• W2010633605 cites W2345324312 @default.
• W2010633605 cites W4210953733 @default.
• W2010633605 cites W4231979654 @default.
• W2010633605 cites W4247325209 @default.
• W2010633605 cites W4361868709 @default.
• W2010633605 cites W45886679 @default.
• W2010633605 doi "https://doi.org/10.1097/med.0b013e328010ca54" @default.
• W2010633605 hasPublicationYear "2006" @default.
• W2010633605 type Work @default.
• W2010633605 sameAs 2010633605 @default.
• W2010633605 citedByCount "2" @default.
• W2010633605 countsByYear W20106336052017 @default.
• W2010633605 crossrefType "journal-article" @default.
• W2010633605 hasAuthorship W2010633605A5023252382 @default.
• W2010633605 hasAuthorship W2010633605A5077353164 @default.
• W2010633605 hasConcept C112672928 @default.
• W2010633605 hasConcept C126322002 @default.
• W2010633605 hasConcept C134018914 @default.
• W2010633605 hasConcept C172268261 @default.
• W2010633605 hasConcept C172680121 @default.
• W2010633605 hasConcept C2779083892 @default.
• W2010633605 hasConcept C2779134260 @default.
• W2010633605 hasConcept C2779234561 @default.
• W2010633605 hasConcept C2780841215 @default.
• W2010633605 hasConcept C42407357 @default.
• W2010633605 hasConcept C54355233 @default.
• W2010633605 hasConcept C551997983 @default.
• W2010633605 hasConcept C71924100 @default.
• W2010633605 hasConcept C86803240 @default.
• W2010633605 hasConceptScore W2010633605C112672928 @default.
• W2010633605 hasConceptScore W2010633605C126322002 @default.
• W2010633605 hasConceptScore W2010633605C134018914 @default.
• W2010633605 hasConceptScore W2010633605C172268261 @default.

• next