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• W2010636701 abstract "Les gliomes nasaux ou hétérotopies nasales sont des tumeurs congénitales rares de la ligne médiane, non héréditaires, composées de tissu neuroglial hétérotopique. L’évaluation initiale doit comprendre un examen tomodensitométrique et/ou par résonance magnétique (IRM), afin d’éliminer une extension intracrânienne. Les principaux diagnostics différentiels concernent les anomalies du développement de l’espace prénasal et regroupent les méningo-encéphalocèles naso-ethmoïdaux, les kystes épidermoïdes et dermoïdes. Le diagnostic différentiel avec un hémangiome nasal (ou angiome Cyrano), peut être difficile. Nous rapportons le cas d’un enfant présentant un gliome nasal paramédian et nous proposons une analyse embryologique et clinique de cette pathologie. Les gliomes nasaux sont rares et entrent dans le cadre des dysraphies médianes. Les principales théories embryopathogéniques sont passées en revue. Celle de l’espace prénasal, décrite par Grünwald en 1910, propose un continuum embryopathogénique entre les encéphalocèles, les gliomes nasaux et les kystes dermoïdes de même topographie. Les travaux récents d’embryologie expérimentale montrent que cette théorie est insuffisante pour les kystes dermoïdes. La connaissance des mécanismes embryologiques impliqués dans la pathogénie de l’hétérotopie gliale nasale devraient permettre une prise en charge thérapeutique adaptée. Nasal gliomas or heterotopia are nonhereditary congenital malformations composed of heterotopic neuroglial tissue. They usually present in infancy. Evaluation should include preoperative imaging with CT scan and/or MRI to rule out intracranial extension. There have been several cases reported in which nasal gliomas were misdiagnosed as capillary hemangiomas. The differential diagnosis includes prenasal space developmental impairment, which are nasoethmoidal meningoencephaloceles, nasal dermoid and epidermoid cysts. We describe the case of a newborn male infant presenting at birth with a paramedial nasal glioma. An embryological and clinical analysis of nasal gliomas is proposed. Nasal glioma is an uncommon congenital lesion presenting as a large panel of midline craniofacial anomalies. The embryological and anatomical origins of nasal gliomas are reviewed. The most known embryological theory was described by Grünwald in 1910 and is called the “prenasal space” theory. This theory is very attractive because of the embryopathogenic continuum proposed among dermoids, gliomas, and encephaloceles. In this article, we discuss major embryological theories on nasal gliomas pathogenesis and propose that while the prenasal space theory can explain the occurrence and the continuum between basal anterior or prenasal encephaloceles and gliomas, it cannot explain the occurrence of craniofacial demoids of the same topography. Better knowledge of embryological mechanisms implicated in the pathogenesis of nasal gliomas can help clinical management of this kind of malformations." @default.
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• W2010636701 date "2006-01-01" @default.
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• W2010636701 title "Hétérotopie gliale nasale : approches clinique et embryologique" @default.
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• W2010636701 doi "https://doi.org/10.1016/s0035-1768(06)76981-9" @default.
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