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- W2010706739 abstract "Genome sequences and gene-expression data from representatives of five distinct lineages of African cichlid fish reveal signatures of the genomic changes that underlie the astounding cichlid diversity seen today. See Article p.375 The 2,000 or so species of cichlid fish, to be found in the lakes and rivers of Africa's Rift Valley, provide the classic example of adaptive radiations. This large-scale international collaboration has sequenced and analysed the genomes and transcriptomes of five distinct lineages of African cichlids. The data reveal an excess of gene duplications in comparison to other fish species. There is an abundance of non-coding element divergence; accelerated coding sequence evolution; expression divergence associated with transposable element insertions in orthologous gene pairs; and regulation by novel miRNAs. Sequencing data from sixty individuals from six closely related Lake Victoria species point to rapid cichlid speciation associated with genome-wide diversifying selection on coding and regulatory variants, and imply that ancient periods of relaxed purifying selection enabled the accumulation of standing variation, which may have been important in facilitating diversification." @default.
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- W2010706739 date "2014-09-01" @default.
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- W2010706739 title "Radiating genomes" @default.
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- W2010706739 doi "https://doi.org/10.1038/nature13742" @default.
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