Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010707512> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2010707512 endingPage "99" @default.
- W2010707512 startingPage "85" @default.
- W2010707512 abstract "Tcte2 (t complex testes expressed 2) is a male meiosis-specific gene that maps to band 3.3 of mouse chromosome 17. Two distinct male fertility defects, hybrid sterility and transmission ratio distortion, have previously been mapped to this region. Hybrid sterility arises in crosses between different mouse species and the F1 generation males have defects in the first meiotic division and are sterile. Transmission ratio distortion is shown by males heterozygous for the t haplotype form of chromosome 17 and is a type of meiotic drive in which male gametes function unequally at fertilization. The Tcte2 gene expresses a coding mRNA and a number of putative non-ORF transcripts in meiosis I. A deletion of the 5′ part of the locus abolishes Tcte2 expression on the t haplotype form of chromosome 17. Additionally, the series of putative non-ORF RNAs at the Tcte2 locus are differentially spliced in species that show hybrid sterility when crossed to laboratory mice. The identification of polymorphisms in t haplotypes and in different mouse species allows alleles of Tcte2 to be proposed as candidates for loci which contribute to both meiotic drive and hybrid sterility phenotypes. While theoretical considerations have previously been used to propose that speciation and meiotic drive involve alleles of the same genes, Tcte2 is the first cloned candidate gene to support this link at a molecular level." @default.
- W2010707512 created "2016-06-24" @default.
- W2010707512 creator A5046008529 @default.
- W2010707512 creator A5078461337 @default.
- W2010707512 date "1997-06-01" @default.
- W2010707512 modified "2023-10-02" @default.
- W2010707512 title "Identification of a male meiosis-specific gene, Tcte2, which is differentially spliced in species that form sterile hybrids with laboratory mice and deleted in t chromosomes showing meiotic drive" @default.
- W2010707512 cites W103371265 @default.
- W2010707512 cites W1542585825 @default.
- W2010707512 cites W1599642664 @default.
- W2010707512 cites W1849418340 @default.
- W2010707512 cites W1903563740 @default.
- W2010707512 cites W1961602847 @default.
- W2010707512 cites W1965072420 @default.
- W2010707512 cites W1970930870 @default.
- W2010707512 cites W1977565627 @default.
- W2010707512 cites W1983942657 @default.
- W2010707512 cites W1988276360 @default.
- W2010707512 cites W1988979372 @default.
- W2010707512 cites W2013094037 @default.
- W2010707512 cites W2037842315 @default.
- W2010707512 cites W2045706605 @default.
- W2010707512 cites W2049964127 @default.
- W2010707512 cites W2052560322 @default.
- W2010707512 cites W2056478819 @default.
- W2010707512 cites W2068446924 @default.
- W2010707512 cites W2068974811 @default.
- W2010707512 cites W2073001975 @default.
- W2010707512 cites W2083207182 @default.
- W2010707512 cites W2083570769 @default.
- W2010707512 cites W2101624747 @default.
- W2010707512 cites W2109698267 @default.
- W2010707512 cites W2122398875 @default.
- W2010707512 cites W2123741601 @default.
- W2010707512 cites W2124732634 @default.
- W2010707512 cites W2146207251 @default.
- W2010707512 cites W2152262375 @default.
- W2010707512 cites W2152810225 @default.
- W2010707512 cites W2161287363 @default.
- W2010707512 cites W2262007220 @default.
- W2010707512 cites W2336705950 @default.
- W2010707512 cites W2398225480 @default.
- W2010707512 doi "https://doi.org/10.1006/dbio.1997.8574" @default.
- W2010707512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9188755" @default.
- W2010707512 hasPublicationYear "1997" @default.
- W2010707512 type Work @default.
- W2010707512 sameAs 2010707512 @default.
- W2010707512 citedByCount "24" @default.
- W2010707512 countsByYear W20107075122018 @default.
- W2010707512 countsByYear W20107075122019 @default.
- W2010707512 countsByYear W20107075122020 @default.
- W2010707512 countsByYear W20107075122022 @default.
- W2010707512 crossrefType "journal-article" @default.
- W2010707512 hasAuthorship W2010707512A5046008529 @default.
- W2010707512 hasAuthorship W2010707512A5078461337 @default.
- W2010707512 hasBestOaLocation W20107075121 @default.
- W2010707512 hasConcept C104317684 @default.
- W2010707512 hasConcept C148196450 @default.
- W2010707512 hasConcept C180754005 @default.
- W2010707512 hasConcept C197754878 @default.
- W2010707512 hasConcept C2776687438 @default.
- W2010707512 hasConcept C54355233 @default.
- W2010707512 hasConcept C54809848 @default.
- W2010707512 hasConcept C84597430 @default.
- W2010707512 hasConcept C86803240 @default.
- W2010707512 hasConceptScore W2010707512C104317684 @default.
- W2010707512 hasConceptScore W2010707512C148196450 @default.
- W2010707512 hasConceptScore W2010707512C180754005 @default.
- W2010707512 hasConceptScore W2010707512C197754878 @default.
- W2010707512 hasConceptScore W2010707512C2776687438 @default.
- W2010707512 hasConceptScore W2010707512C54355233 @default.
- W2010707512 hasConceptScore W2010707512C54809848 @default.
- W2010707512 hasConceptScore W2010707512C84597430 @default.
- W2010707512 hasConceptScore W2010707512C86803240 @default.
- W2010707512 hasIssue "1" @default.
- W2010707512 hasLocation W20107075121 @default.
- W2010707512 hasLocation W20107075122 @default.
- W2010707512 hasOpenAccess W2010707512 @default.
- W2010707512 hasPrimaryLocation W20107075121 @default.
- W2010707512 hasRelatedWork W1551477413 @default.
- W2010707512 hasRelatedWork W1845110652 @default.
- W2010707512 hasRelatedWork W1982749768 @default.
- W2010707512 hasRelatedWork W2026258702 @default.
- W2010707512 hasRelatedWork W2038283596 @default.
- W2010707512 hasRelatedWork W2057739827 @default.
- W2010707512 hasRelatedWork W2073937565 @default.
- W2010707512 hasRelatedWork W2074555261 @default.
- W2010707512 hasRelatedWork W2124448918 @default.
- W2010707512 hasRelatedWork W2155294402 @default.
- W2010707512 hasVolume "186" @default.
- W2010707512 isParatext "false" @default.
- W2010707512 isRetracted "false" @default.
- W2010707512 magId "2010707512" @default.
- W2010707512 workType "article" @default.