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• W2010708694 abstract "Highly efficient organic reactions in water are important for designing environmental-friendly and low cost synthetic processes. Herein, we demonstrate an intermediate-in-water strategy for the heterogeneous synthesis of benzofurans in aqueous media. The cyclization reaction of 2-(phenylethynyl)phenol to 2-phenylbenzofuran cannot proceed in pure water. However, this reaction can be efficiently promoted by the formation of sparingly soluble intermediate in the presence of alkaline. Quantitative conversion of a variety of substrates to benzofuran derivatives has been achieved in the absence of noble metal catalyst. Other remarkable features including easy-isolation and purification of product, along with wide range of functional group tolerance render the methodology promising in the realm of green-synthesis." @default.
• W2010708694 created "2016-06-24" @default.
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• W2010708694 date "2014-06-01" @default.
• W2010708694 modified "2023-10-14" @default.
• W2010708694 title "Highly efficient heterogeneous synthesis of benzofurans under aqueous condition" @default.
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• W2010708694 doi "https://doi.org/10.1016/j.tet.2014.04.005" @default.
• W2010708694 hasPublicationYear "2014" @default.
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