Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010750158> ?p ?o ?g. }
- W2010750158 endingPage "5" @default.
- W2010750158 startingPage "1" @default.
- W2010750158 abstract "Protein energy wasting is frequently observed in patients with advanced chronic renal failure and end-stage renal disease. Anorexia and reduced food intake are critical contributing factors and negatively impact on patients' survival. Ghrelin is a prophagic peptide produced by the stomach and acting at the hypothalamic level to increase the activity of orexigenic neurons. In patients with chronic renal disease, plasma levels are increased as a likely effect of reduced renal clearance. Nevertheless, patients' food intake is significantly reduced, suggesting inflammation-mediated resistance of hypothalamic nuclei to peripheral signals. A number of forms of evidence show that ghrelin resistance could be overcome by the administration of exogenous ghrelin. Therefore, ghrelin has been proposed as a potential strategy to improve food intake in chronic renal failure patients with protein energy wasting. Preliminary data are encouraging although larger prospective clinical trials are needed to confirm the results and to identify those patients who are likely to benefit most from the administration of exogenous ghrelin." @default.
- W2010750158 created "2016-06-24" @default.
- W2010750158 creator A5001774509 @default.
- W2010750158 creator A5045164292 @default.
- W2010750158 creator A5046484248 @default.
- W2010750158 creator A5046818039 @default.
- W2010750158 creator A5068388301 @default.
- W2010750158 creator A5090948585 @default.
- W2010750158 date "2010-02-04" @default.
- W2010750158 modified "2023-09-26" @default.
- W2010750158 title "Chronic Renal Failure, Cachexia, and Ghrelin" @default.
- W2010750158 cites W1971484222 @default.
- W2010750158 cites W1974108171 @default.
- W2010750158 cites W1980792788 @default.
- W2010750158 cites W1981025527 @default.
- W2010750158 cites W1989169668 @default.
- W2010750158 cites W1991429524 @default.
- W2010750158 cites W2003064100 @default.
- W2010750158 cites W2010371973 @default.
- W2010750158 cites W2020843850 @default.
- W2010750158 cites W2026104660 @default.
- W2010750158 cites W2026358146 @default.
- W2010750158 cites W2031440388 @default.
- W2010750158 cites W2035426136 @default.
- W2010750158 cites W2041107250 @default.
- W2010750158 cites W2056065157 @default.
- W2010750158 cites W2068914724 @default.
- W2010750158 cites W2082113374 @default.
- W2010750158 cites W2084834028 @default.
- W2010750158 cites W2085373178 @default.
- W2010750158 cites W2087076688 @default.
- W2010750158 cites W2094588238 @default.
- W2010750158 cites W2096239574 @default.
- W2010750158 cites W2097265990 @default.
- W2010750158 cites W2102026963 @default.
- W2010750158 cites W2111253761 @default.
- W2010750158 cites W2111736055 @default.
- W2010750158 cites W2113945706 @default.
- W2010750158 cites W2116454569 @default.
- W2010750158 cites W2132422631 @default.
- W2010750158 cites W2132748505 @default.
- W2010750158 cites W2134456501 @default.
- W2010750158 cites W2144547370 @default.
- W2010750158 cites W2148416248 @default.
- W2010750158 cites W2149181234 @default.
- W2010750158 cites W2150509255 @default.
- W2010750158 cites W2152643580 @default.
- W2010750158 cites W2152835975 @default.
- W2010750158 cites W2156297823 @default.
- W2010750158 cites W2156386130 @default.
- W2010750158 cites W2164239270 @default.
- W2010750158 cites W2168293740 @default.
- W2010750158 doi "https://doi.org/10.1155/2010/648045" @default.
- W2010750158 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2925092" @default.
- W2010750158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20798758" @default.
- W2010750158 hasPublicationYear "2010" @default.
- W2010750158 type Work @default.
- W2010750158 sameAs 2010750158 @default.
- W2010750158 citedByCount "16" @default.
- W2010750158 countsByYear W20107501582012 @default.
- W2010750158 countsByYear W20107501582013 @default.
- W2010750158 countsByYear W20107501582014 @default.
- W2010750158 countsByYear W20107501582015 @default.
- W2010750158 countsByYear W20107501582018 @default.
- W2010750158 countsByYear W20107501582019 @default.
- W2010750158 crossrefType "journal-article" @default.
- W2010750158 hasAuthorship W2010750158A5001774509 @default.
- W2010750158 hasAuthorship W2010750158A5045164292 @default.
- W2010750158 hasAuthorship W2010750158A5046484248 @default.
- W2010750158 hasAuthorship W2010750158A5046818039 @default.
- W2010750158 hasAuthorship W2010750158A5068388301 @default.
- W2010750158 hasAuthorship W2010750158A5090948585 @default.
- W2010750158 hasBestOaLocation W20107501581 @default.
- W2010750158 hasConcept C118303440 @default.
- W2010750158 hasConcept C121608353 @default.
- W2010750158 hasConcept C126322002 @default.
- W2010750158 hasConcept C134018914 @default.
- W2010750158 hasConcept C170493617 @default.
- W2010750158 hasConcept C2777205416 @default.
- W2010750158 hasConcept C2777704314 @default.
- W2010750158 hasConcept C2778654693 @default.
- W2010750158 hasConcept C2779134260 @default.
- W2010750158 hasConcept C2779357093 @default.
- W2010750158 hasConcept C2779764123 @default.
- W2010750158 hasConcept C71315377 @default.
- W2010750158 hasConcept C71924100 @default.
- W2010750158 hasConcept C75908981 @default.
- W2010750158 hasConcept C93984277 @default.
- W2010750158 hasConceptScore W2010750158C118303440 @default.
- W2010750158 hasConceptScore W2010750158C121608353 @default.
- W2010750158 hasConceptScore W2010750158C126322002 @default.
- W2010750158 hasConceptScore W2010750158C134018914 @default.
- W2010750158 hasConceptScore W2010750158C170493617 @default.
- W2010750158 hasConceptScore W2010750158C2777205416 @default.
- W2010750158 hasConceptScore W2010750158C2777704314 @default.
- W2010750158 hasConceptScore W2010750158C2778654693 @default.
- W2010750158 hasConceptScore W2010750158C2779134260 @default.
- W2010750158 hasConceptScore W2010750158C2779357093 @default.