Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010751104> ?p ?o ?g. }
- W2010751104 endingPage "344" @default.
- W2010751104 startingPage "340" @default.
- W2010751104 abstract "Protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 (PCMT1) gene encodes for the protein repair enzyme L-isoaspartate (D-aspartate) O-methyltransferase (PIMT), which is known to protect certain neural cells from Bax-induced apoptosis. Previous study has shown that PCMT1 polymorphisms rs4552 and rs4816 of infant are associated with spina bifida in the Californian population. The association between maternal polymorphism and neural tube defects is still uncovered. A case-control study was conducted to investigate a possible association between maternal PCMT1 and NTDs in Lvliang high-risk area of Shanxi Province in China, using a high-resolution DNA melting analysis genotyping method. We found that increased risk for anencephaly in isolated NTDs compared with the normal control group was observed for the G (vs. A) allele (p=0.034, OR=1.896, 95% CI, 1.04-3.45) and genotypes GG+GA (p=0.025, OR=2.237, 95% CI, 1.09-4.57). Although the significance was lost after multiple comparison correction, the results implied that maternal polymorphisms in PCMT1 might be a potential genetic risk factor for isolated anencephaly in this Chinese population." @default.
- W2010751104 created "2016-06-24" @default.
- W2010751104 creator A5002661071 @default.
- W2010751104 creator A5010806417 @default.
- W2010751104 creator A5010956456 @default.
- W2010751104 creator A5012278873 @default.
- W2010751104 creator A5021149804 @default.
- W2010751104 creator A5035715471 @default.
- W2010751104 creator A5039088967 @default.
- W2010751104 creator A5039717240 @default.
- W2010751104 creator A5051481992 @default.
- W2010751104 creator A5052115159 @default.
- W2010751104 creator A5071854723 @default.
- W2010751104 creator A5075124603 @default.
- W2010751104 creator A5088174174 @default.
- W2010751104 date "2012-09-01" @default.
- W2010751104 modified "2023-09-22" @default.
- W2010751104 title "Maternal PCMT1 gene polymorphisms and the risk of neural tube defects in a Chinese population of Lvliang high-risk area" @default.
- W2010751104 cites W1841821181 @default.
- W2010751104 cites W1921661894 @default.
- W2010751104 cites W1970857676 @default.
- W2010751104 cites W1976312565 @default.
- W2010751104 cites W1977298273 @default.
- W2010751104 cites W2001005123 @default.
- W2010751104 cites W2003014235 @default.
- W2010751104 cites W2006492967 @default.
- W2010751104 cites W2019374625 @default.
- W2010751104 cites W2028767039 @default.
- W2010751104 cites W2038875321 @default.
- W2010751104 cites W2050013837 @default.
- W2010751104 cites W2058266446 @default.
- W2010751104 cites W2061016075 @default.
- W2010751104 cites W2070538961 @default.
- W2010751104 cites W2075558318 @default.
- W2010751104 cites W2076223802 @default.
- W2010751104 cites W2085514791 @default.
- W2010751104 cites W2092671261 @default.
- W2010751104 cites W2096765959 @default.
- W2010751104 cites W2100472643 @default.
- W2010751104 cites W2103953947 @default.
- W2010751104 cites W2107503906 @default.
- W2010751104 cites W2107935380 @default.
- W2010751104 cites W2110178075 @default.
- W2010751104 cites W2116403786 @default.
- W2010751104 cites W2117424414 @default.
- W2010751104 cites W2118105680 @default.
- W2010751104 cites W2126718711 @default.
- W2010751104 cites W2130826341 @default.
- W2010751104 cites W2131496660 @default.
- W2010751104 cites W2135465326 @default.
- W2010751104 cites W2147362161 @default.
- W2010751104 cites W2157982958 @default.
- W2010751104 cites W2159796328 @default.
- W2010751104 cites W2160165018 @default.
- W2010751104 cites W2162530578 @default.
- W2010751104 cites W2162664608 @default.
- W2010751104 cites W2171193990 @default.
- W2010751104 cites W2325417132 @default.
- W2010751104 cites W2045845968 @default.
- W2010751104 doi "https://doi.org/10.1016/j.gene.2012.05.035" @default.
- W2010751104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22647835" @default.
- W2010751104 hasPublicationYear "2012" @default.
- W2010751104 type Work @default.
- W2010751104 sameAs 2010751104 @default.
- W2010751104 citedByCount "6" @default.
- W2010751104 countsByYear W20107511042013 @default.
- W2010751104 countsByYear W20107511042017 @default.
- W2010751104 countsByYear W20107511042020 @default.
- W2010751104 countsByYear W20107511042021 @default.
- W2010751104 countsByYear W20107511042022 @default.
- W2010751104 crossrefType "journal-article" @default.
- W2010751104 hasAuthorship W2010751104A5002661071 @default.
- W2010751104 hasAuthorship W2010751104A5010806417 @default.
- W2010751104 hasAuthorship W2010751104A5010956456 @default.
- W2010751104 hasAuthorship W2010751104A5012278873 @default.
- W2010751104 hasAuthorship W2010751104A5021149804 @default.
- W2010751104 hasAuthorship W2010751104A5035715471 @default.
- W2010751104 hasAuthorship W2010751104A5039088967 @default.
- W2010751104 hasAuthorship W2010751104A5039717240 @default.
- W2010751104 hasAuthorship W2010751104A5051481992 @default.
- W2010751104 hasAuthorship W2010751104A5052115159 @default.
- W2010751104 hasAuthorship W2010751104A5071854723 @default.
- W2010751104 hasAuthorship W2010751104A5075124603 @default.
- W2010751104 hasAuthorship W2010751104A5088174174 @default.
- W2010751104 hasConcept C104317684 @default.
- W2010751104 hasConcept C126322002 @default.
- W2010751104 hasConcept C135763542 @default.
- W2010751104 hasConcept C156957248 @default.
- W2010751104 hasConcept C180754005 @default.
- W2010751104 hasConcept C196843134 @default.
- W2010751104 hasConcept C2776394550 @default.
- W2010751104 hasConcept C2778478650 @default.
- W2010751104 hasConcept C2780594696 @default.
- W2010751104 hasConcept C2908647359 @default.
- W2010751104 hasConcept C31467283 @default.
- W2010751104 hasConcept C34372108 @default.
- W2010751104 hasConcept C54355233 @default.
- W2010751104 hasConcept C71924100 @default.