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- W2010752723 abstract "Abstract The dissociation and partitioning behaviour of Progabide and one of its degradation products, SL79.182, were investigated. Progabide was found to be amphoteric with pKa values of 3.41 and 12.95. SL79.182 behaved as a typical weak acid with a pKa value of 8.94. The apparent partition coefficient-pH profile of Progabide for the water/n-octanol system was assessed by the filter-probe extractor method whereas that of SL79.182 was determined by the shake-flask method. Log (P) values of 2.97 for Progabide and 4.04 for SL79.182 were derived." @default.
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- W2010752723 date "1988-10-01" @default.
- W2010752723 modified "2023-09-27" @default.
- W2010752723 title "Dissociation and partitioning of Progabide and its degradation product" @default.
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- W2010752723 doi "https://doi.org/10.1016/0378-5173(88)90083-x" @default.
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