FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010753605> ?p ?o ?g. }

• W2010753605 endingPage "777" @default.
• W2010753605 startingPage "772" @default.
• W2010753605 abstract "DONOVAN, C. M., and M. J. PAGLIASSOTTI. Quantitative assessment of pathways for lactate disposal in skeletal muscle fiber types. Med. Sci. Sports Exerc., Vol. 32, No. 4, pp. 772–777, 2000. Quantifying the contribution of the various skeletal muscle fiber types toward lactate disposal has proven elusive. In part, this can be attributed to the lack of adequate preparations for the study of all potential metabolic pathways involved. Toward this end our laboratory developed several perfused muscle preparations that are homogeneous for specific fiber types. This paper briefly reviews our findings regarding the influence of fiber type on lactate disposal in resting skeletal muscle and the metabolic pathways involved. Perfusing over a range of lactate concentrations, 1–12 mM, all fiber types were shown to switch from net production at low lactate concentrations to net consumption at higher concentrations. This transition occurred at lower lactate concentrations for Type I and IIa fibers, when compared with IIb fibers. For Type I and IIa fibers oxidation was observed to be the primary route of disposal accounting for approximately 50% of the lactate removed. For all fiber types, transamination was a significant pathway for the disposal of lactate carbon, whereas glyconeogenesis was the primary pathway for disposal in Type IIb fibers. The glyconeogenic capacity was quantitatively similar for Type IIa and IIb fibers but was negligible for Type I fibers. The pathway for glyconeogenesis in skeletal muscle was shown to be substantially different from that employed in hepatic glyconeogenesis. Results indicated that neither the TCA cycle nor phosphoenolpyruvate carboxykinase is involved in skeletal muscle glyconeogenesis. Our findings suggested that PEP formation in skeletal muscle glyconeogenesis occurs by “reversal” of the pyruvate kinase reaction." @default.
• W2010753605 created "2016-06-24" @default.
• W2010753605 creator A5027969739 @default.
• W2010753605 creator A5054009279 @default.
• W2010753605 date "2000-04-01" @default.
• W2010753605 modified "2023-10-03" @default.
• W2010753605 title "Quantitative assessment of pathways for lactate disposal in skeletal muscle fiber types" @default.
• W2010753605 cites W1518013360 @default.
• W2010753605 cites W1554211606 @default.
• W2010753605 cites W157750308 @default.
• W2010753605 cites W1595350639 @default.
• W2010753605 cites W172427808 @default.
• W2010753605 cites W1774598976 @default.
• W2010753605 cites W1918835191 @default.
• W2010753605 cites W1963940227 @default.
• W2010753605 cites W1966262907 @default.
• W2010753605 cites W1966947066 @default.
• W2010753605 cites W1991928071 @default.
• W2010753605 cites W2022295275 @default.
• W2010753605 cites W2022558995 @default.
• W2010753605 cites W206752494 @default.
• W2010753605 cites W2071642479 @default.
• W2010753605 cites W2076577119 @default.
• W2010753605 cites W2090651993 @default.
• W2010753605 cites W2122279626 @default.
• W2010753605 cites W2273703360 @default.
• W2010753605 cites W2284469596 @default.
• W2010753605 cites W2287671349 @default.
• W2010753605 cites W2305919687 @default.
• W2010753605 cites W2399146540 @default.
• W2010753605 cites W2414851192 @default.
• W2010753605 cites W98623729 @default.
• W2010753605 doi "https://doi.org/10.1097/00005768-200004000-00009" @default.
• W2010753605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10776896" @default.
• W2010753605 hasPublicationYear "2000" @default.
• W2010753605 type Work @default.
• W2010753605 sameAs 2010753605 @default.
• W2010753605 citedByCount "64" @default.
• W2010753605 countsByYear W20107536052012 @default.
• W2010753605 countsByYear W20107536052013 @default.
• W2010753605 countsByYear W20107536052014 @default.
• W2010753605 countsByYear W20107536052015 @default.
• W2010753605 countsByYear W20107536052016 @default.
• W2010753605 countsByYear W20107536052017 @default.
• W2010753605 countsByYear W20107536052018 @default.
• W2010753605 countsByYear W20107536052019 @default.
• W2010753605 countsByYear W20107536052020 @default.
• W2010753605 countsByYear W20107536052022 @default.
• W2010753605 countsByYear W20107536052023 @default.
• W2010753605 crossrefType "journal-article" @default.
• W2010753605 hasAuthorship W2010753605A5027969739 @default.
• W2010753605 hasAuthorship W2010753605A5054009279 @default.
• W2010753605 hasBestOaLocation W20107536051 @default.
• W2010753605 hasConcept C126322002 @default.
• W2010753605 hasConcept C134018914 @default.
• W2010753605 hasConcept C143937172 @default.
• W2010753605 hasConcept C178790620 @default.
• W2010753605 hasConcept C181199279 @default.
• W2010753605 hasConcept C185592680 @default.
• W2010753605 hasConcept C192989942 @default.
• W2010753605 hasConcept C20251656 @default.
• W2010753605 hasConcept C20904676 @default.
• W2010753605 hasConcept C2775920511 @default.
• W2010753605 hasConcept C2777318727 @default.
• W2010753605 hasConcept C2779959927 @default.
• W2010753605 hasConcept C3020730638 @default.
• W2010753605 hasConcept C515207424 @default.
• W2010753605 hasConcept C519885992 @default.
• W2010753605 hasConcept C523546767 @default.
• W2010753605 hasConcept C54355233 @default.
• W2010753605 hasConcept C55493867 @default.
• W2010753605 hasConcept C62231903 @default.
• W2010753605 hasConcept C68793091 @default.
• W2010753605 hasConcept C71924100 @default.
• W2010753605 hasConcept C86803240 @default.
• W2010753605 hasConceptScore W2010753605C126322002 @default.
• W2010753605 hasConceptScore W2010753605C134018914 @default.
• W2010753605 hasConceptScore W2010753605C143937172 @default.
• W2010753605 hasConceptScore W2010753605C178790620 @default.
• W2010753605 hasConceptScore W2010753605C181199279 @default.
• W2010753605 hasConceptScore W2010753605C185592680 @default.
• W2010753605 hasConceptScore W2010753605C192989942 @default.
• W2010753605 hasConceptScore W2010753605C20251656 @default.
• W2010753605 hasConceptScore W2010753605C20904676 @default.
• W2010753605 hasConceptScore W2010753605C2775920511 @default.
• W2010753605 hasConceptScore W2010753605C2777318727 @default.
• W2010753605 hasConceptScore W2010753605C2779959927 @default.
• W2010753605 hasConceptScore W2010753605C3020730638 @default.
• W2010753605 hasConceptScore W2010753605C515207424 @default.
• W2010753605 hasConceptScore W2010753605C519885992 @default.
• W2010753605 hasConceptScore W2010753605C523546767 @default.
• W2010753605 hasConceptScore W2010753605C54355233 @default.
• W2010753605 hasConceptScore W2010753605C55493867 @default.
• W2010753605 hasConceptScore W2010753605C62231903 @default.
• W2010753605 hasConceptScore W2010753605C68793091 @default.
• W2010753605 hasConceptScore W2010753605C71924100 @default.
• W2010753605 hasConceptScore W2010753605C86803240 @default.
• W2010753605 hasIssue "4" @default.

• next