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- W2010765407 abstract "Taking advantage of the effects on DNA secondary structure of two DNA-intercalators, ethidium bromide and chloroquine, we used each of them to treat nuclei from both mature erythrocytes and reticulocytes of chicken, as an alternative approach to study the relationships between DNA secondary structure, nuclear proteins and chromatin structure. We presented results of differential extraction of nuclear proteins from nuclei with DNA-intercalators, as well as preliminary characterization of these proteins. A 45kd protein is the major component in fractions extracted by both intercalators from nuclei from either mature erythrocytes or reticulocytes and seems to be a DNA-binding protein. Furthermore, from current concepts of functional aspects of DNA conformation and structural heterogeneity in chromatin and nuclear proteins, we have discussed both the significance of our resuits as well as technical aspects of this approach." @default.
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- W2010765407 title "The effects of DNA intercalators on chromatin of chicken red blood cells --- differential extraction on nonhistone proteins" @default.
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- W2010765407 doi "https://doi.org/10.1038/cr.1990.11" @default.
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