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• W2010778222 endingPage "1308" @default.
• W2010778222 startingPage "1291" @default.
• W2010778222 abstract "The medial division of the central nucleus of the amygdala (CeAM) and the lateral division of the bed nucleus of the stria terminalis (BNSTL) are closely related. Both receive projections from the basolateral amygdala (BLA) and both project to brain areas that mediate fear-influenced behaviors. In contrast to CeAM however, initial attempts to implicate the BNST in conditioned fear responses were largely unsuccessful. More recent studies have shown that the BNST does participate in some types of anxiety and stress responses. Here, we review evidence suggesting that the CeAM and BNSTL are functionally complementary, with CeAM mediating short- but not long-duration threat responses (i.e., phasic fear) and BNSTL mediating long- but not short-duration responses (sustained fear or ‘anxiety’). We also review findings implicating the stress-related peptide corticotropin-releasing factor (CRF) in sustained but not phasic threat responses, and attempt to integrate these findings into a neural circuit model which accounts for these and related observations." @default.
• W2010778222 created "2016-06-24" @default.
• W2010778222 creator A5020998015 @default.
• W2010778222 creator A5074155368 @default.
• W2010778222 creator A5079421218 @default.
• W2010778222 date "2009-11-01" @default.
• W2010778222 modified "2023-10-18" @default.
• W2010778222 title "Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses" @default.
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