Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010793433> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2010793433 endingPage "345" @default.
- W2010793433 startingPage "335" @default.
- W2010793433 abstract "To further define the possible inteactions of carcinogenic chemicals and the prostate gland, the ability of N-hydroxyurethane to enter the prostate and its secretion has been assessed in rats and dogs. In anesthetized rats in which prostatic fluid was collected for up to 6 hr after treatment, N-hydroxyurethane rapidly entered the prostatic fluid following the intravenous administration of doses of 100 mg/kg. The mean gland to plasma ratios for the ventral and dorsolateral lobes of the prostates from these rats were 1.33 and 0.91, respectively, while the prostatic fluid concentrations averaged 0.97 times the mean plasma concentration over the periods of collection. In six unanesthetized dogs, four with prostatic fistulas, the intravenous administration of 100 mg/kg of N-hydroxyurethane resulted in the appearance of the chemical in both the gland and its secretion. The mean gland to plasma ratio for four dogs examined at 120 min after treatment was 2.60, and the mean prostatic fluid to plasma ratio for nine samples of fluid collected from three dogs over the first 120–180 min after treatment was 0.95. Thus, N-hydroxyurethane was found to readily penetrate from plasma into both the prostate gland and the prostatic secretion of the rat and dog." @default.
- W2010793433 created "2016-06-24" @default.
- W2010793433 creator A5037827078 @default.
- W2010793433 creator A5050535065 @default.
- W2010793433 creator A5082984962 @default.
- W2010793433 date "1977-05-01" @default.
- W2010793433 modified "2023-09-26" @default.
- W2010793433 title "The penetration of N-hydroxyurethane into the prostate and prostatic secretion of the rat and dog" @default.
- W2010793433 cites W1456663821 @default.
- W2010793433 cites W1561819277 @default.
- W2010793433 cites W1993074893 @default.
- W2010793433 cites W2048837884 @default.
- W2010793433 cites W2310625879 @default.
- W2010793433 cites W2394700146 @default.
- W2010793433 cites W2418733039 @default.
- W2010793433 cites W297347753 @default.
- W2010793433 cites W57212946 @default.
- W2010793433 cites W583144594 @default.
- W2010793433 doi "https://doi.org/10.1016/0041-008x(77)90105-3" @default.
- W2010793433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/877964" @default.
- W2010793433 hasPublicationYear "1977" @default.
- W2010793433 type Work @default.
- W2010793433 sameAs 2010793433 @default.
- W2010793433 citedByCount "1" @default.
- W2010793433 crossrefType "journal-article" @default.
- W2010793433 hasAuthorship W2010793433A5037827078 @default.
- W2010793433 hasAuthorship W2010793433A5050535065 @default.
- W2010793433 hasAuthorship W2010793433A5082984962 @default.
- W2010793433 hasConcept C121608353 @default.
- W2010793433 hasConcept C126322002 @default.
- W2010793433 hasConcept C126894567 @default.
- W2010793433 hasConcept C127413603 @default.
- W2010793433 hasConcept C134018914 @default.
- W2010793433 hasConcept C185592680 @default.
- W2010793433 hasConcept C2776235491 @default.
- W2010793433 hasConcept C2993530982 @default.
- W2010793433 hasConcept C42475967 @default.
- W2010793433 hasConcept C49039625 @default.
- W2010793433 hasConcept C71924100 @default.
- W2010793433 hasConcept C80107235 @default.
- W2010793433 hasConceptScore W2010793433C121608353 @default.
- W2010793433 hasConceptScore W2010793433C126322002 @default.
- W2010793433 hasConceptScore W2010793433C126894567 @default.
- W2010793433 hasConceptScore W2010793433C127413603 @default.
- W2010793433 hasConceptScore W2010793433C134018914 @default.
- W2010793433 hasConceptScore W2010793433C185592680 @default.
- W2010793433 hasConceptScore W2010793433C2776235491 @default.
- W2010793433 hasConceptScore W2010793433C2993530982 @default.
- W2010793433 hasConceptScore W2010793433C42475967 @default.
- W2010793433 hasConceptScore W2010793433C49039625 @default.
- W2010793433 hasConceptScore W2010793433C71924100 @default.
- W2010793433 hasConceptScore W2010793433C80107235 @default.
- W2010793433 hasIssue "2" @default.
- W2010793433 hasLocation W20107934331 @default.
- W2010793433 hasLocation W20107934332 @default.
- W2010793433 hasOpenAccess W2010793433 @default.
- W2010793433 hasPrimaryLocation W20107934331 @default.
- W2010793433 hasRelatedWork W1966296538 @default.
- W2010793433 hasRelatedWork W1988109684 @default.
- W2010793433 hasRelatedWork W2020884724 @default.
- W2010793433 hasRelatedWork W2074268135 @default.
- W2010793433 hasRelatedWork W2090408064 @default.
- W2010793433 hasRelatedWork W2161296685 @default.
- W2010793433 hasRelatedWork W2410537918 @default.
- W2010793433 hasRelatedWork W2748952813 @default.
- W2010793433 hasRelatedWork W2953262584 @default.
- W2010793433 hasRelatedWork W4255681344 @default.
- W2010793433 hasVolume "40" @default.
- W2010793433 isParatext "false" @default.
- W2010793433 isRetracted "false" @default.
- W2010793433 magId "2010793433" @default.
- W2010793433 workType "article" @default.