FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010793934> ?p ?o ?g. }

• W2010793934 endingPage "978" @default.
• W2010793934 startingPage "968" @default.
• W2010793934 abstract "Many synaptotagmins are Ca2+-binding membrane proteins with functions in Ca2+-triggered exocytosis. Synaptotagmin IV (syt IV) has no Ca2+ binding activity, but nevertheless modulates exocytosis. Here, cell-attached capacitance recording was used to study single vesicle fusion and fission in control and syt IV overexpressing PC12 cells. Unitary capacitance steps varied widely in size, indicating that both microvesicles (MVs) and dense-core vesicles (DCVs) undergo fusion. Syt IV overexpression reduced the size of DCVs and endocytotic vesicles but not MVs. Syt IV also reduced the basal rate of Ca2+-induced fusion. During kiss-and-run, syt IV increased the conductance and duration of DCV fusion pores but not MV fusion pores. During full-fusion of DCVs syt IV increased the fusion pore conductance but not the duration. Syt IV overexpression increased the duration but not the conductance of fission pores during endocytosis. The effects of syt IV on fusion pores in PC12 cells resembled the effects on fusion pores in peptidergic nerve terminals. However, differences between these and results obtained with amperometry may indicate that amperometry and capacitance detect the fusion of different populations of vesicles. The effects of syt IV on fusion pores are discussed in terms of structural models and kinetic mechanisms." @default.
• W2010793934 created "2016-06-24" @default.
• W2010793934 creator A5016673919 @default.
• W2010793934 creator A5045839676 @default.
• W2010793934 creator A5046833465 @default.
• W2010793934 date "2010-03-01" @default.
• W2010793934 modified "2023-10-15" @default.
• W2010793934 title "Synaptotagmin IV Modulation of Vesicle Size and Fusion Pores in PC12 Cells" @default.
• W2010793934 cites W1485367438 @default.
• W2010793934 cites W1599906730 @default.
• W2010793934 cites W1970249565 @default.
• W2010793934 cites W1971457402 @default.
• W2010793934 cites W1975642381 @default.
• W2010793934 cites W1975830464 @default.
• W2010793934 cites W1979272031 @default.
• W2010793934 cites W2001637662 @default.
• W2010793934 cites W2005537077 @default.
• W2010793934 cites W2025828073 @default.
• W2010793934 cites W2026005895 @default.
• W2010793934 cites W2028069387 @default.
• W2010793934 cites W2035070093 @default.
• W2010793934 cites W2037502953 @default.
• W2010793934 cites W2041317493 @default.
• W2010793934 cites W2044679183 @default.
• W2010793934 cites W2058289105 @default.
• W2010793934 cites W2058616059 @default.
• W2010793934 cites W2059171611 @default.
• W2010793934 cites W2061613461 @default.
• W2010793934 cites W2066562577 @default.
• W2010793934 cites W2068323391 @default.
• W2010793934 cites W2069500280 @default.
• W2010793934 cites W2077644186 @default.
• W2010793934 cites W2080384074 @default.
• W2010793934 cites W2083279393 @default.
• W2010793934 cites W2087513927 @default.
• W2010793934 cites W2092562744 @default.
• W2010793934 cites W2096582689 @default.
• W2010793934 cites W2098635427 @default.
• W2010793934 cites W2106723144 @default.
• W2010793934 cites W2106758010 @default.
• W2010793934 cites W2113728164 @default.
• W2010793934 cites W2136422440 @default.
• W2010793934 cites W2150487147 @default.
• W2010793934 cites W2151380386 @default.
• W2010793934 cites W2154649008 @default.
• W2010793934 cites W2161127226 @default.
• W2010793934 doi "https://doi.org/10.1016/j.bpj.2009.11.024" @default.
• W2010793934 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2849050" @default.
• W2010793934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20303854" @default.
• W2010793934 hasPublicationYear "2010" @default.
• W2010793934 type Work @default.
• W2010793934 sameAs 2010793934 @default.
• W2010793934 citedByCount "30" @default.
• W2010793934 countsByYear W20107939342012 @default.
• W2010793934 countsByYear W20107939342013 @default.
• W2010793934 countsByYear W20107939342014 @default.
• W2010793934 countsByYear W20107939342015 @default.
• W2010793934 countsByYear W20107939342016 @default.
• W2010793934 countsByYear W20107939342017 @default.
• W2010793934 countsByYear W20107939342018 @default.
• W2010793934 countsByYear W20107939342019 @default.
• W2010793934 countsByYear W20107939342020 @default.
• W2010793934 countsByYear W20107939342021 @default.
• W2010793934 countsByYear W20107939342022 @default.
• W2010793934 crossrefType "journal-article" @default.
• W2010793934 hasAuthorship W2010793934A5016673919 @default.
• W2010793934 hasAuthorship W2010793934A5045839676 @default.
• W2010793934 hasAuthorship W2010793934A5046833465 @default.
• W2010793934 hasBestOaLocation W20107939341 @default.
• W2010793934 hasConcept C103038307 @default.
• W2010793934 hasConcept C114614502 @default.
• W2010793934 hasConcept C121932024 @default.
• W2010793934 hasConcept C12554922 @default.
• W2010793934 hasConcept C130316041 @default.
• W2010793934 hasConcept C138885662 @default.
• W2010793934 hasConcept C148785051 @default.
• W2010793934 hasConcept C1491633281 @default.
• W2010793934 hasConcept C158525013 @default.
• W2010793934 hasConcept C175969161 @default.
• W2010793934 hasConcept C185592680 @default.
• W2010793934 hasConcept C196330066 @default.
• W2010793934 hasConcept C28005876 @default.
• W2010793934 hasConcept C33923547 @default.
• W2010793934 hasConcept C41625074 @default.
• W2010793934 hasConcept C41895202 @default.
• W2010793934 hasConcept C55493867 @default.
• W2010793934 hasConcept C86473631 @default.
• W2010793934 hasConcept C86803240 @default.
• W2010793934 hasConcept C92488253 @default.
• W2010793934 hasConcept C95444343 @default.
• W2010793934 hasConceptScore W2010793934C103038307 @default.
• W2010793934 hasConceptScore W2010793934C114614502 @default.
• W2010793934 hasConceptScore W2010793934C121932024 @default.
• W2010793934 hasConceptScore W2010793934C12554922 @default.
• W2010793934 hasConceptScore W2010793934C130316041 @default.
• W2010793934 hasConceptScore W2010793934C138885662 @default.
• W2010793934 hasConceptScore W2010793934C148785051 @default.
• W2010793934 hasConceptScore W2010793934C1491633281 @default.

• next