Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010796656> ?p ?o ?g. }
- W2010796656 endingPage "1093" @default.
- W2010796656 startingPage "1086" @default.
- W2010796656 abstract "PLGA porous microspheres loaded with doxorubicin (DOX) and paclitaxel (PTX) were developed for in situ treatment of metastatic lung cancer. The synergistic effect of the combined drugs was investigated against B16F10 cells to obtain the optimal prescription for in vivo studies. The combination therapy showed great synergism when DOX was the majority in the combination therapy, while they showed moderate antagonism when PTX is in major. The combination of DOX and PTX at a molar ratio of 5/1 showed the best synergistic therapeutic effect in the free form. However, the drugs exhibited more synergism in the PLGA microspheres at a molar ratio of 2/1, due to the difference in drug release rate. The in vivo study verified the synergism of DOX and PTX at the optimal molar ratio. These results suggested that dual encapsulation of DOX and PTX in porous PLGA microspheres would be a promising technology for long effective lung cancer treatment." @default.
- W2010796656 created "2016-06-24" @default.
- W2010796656 creator A5000852341 @default.
- W2010796656 creator A5005035675 @default.
- W2010796656 creator A5005243346 @default.
- W2010796656 creator A5015423597 @default.
- W2010796656 creator A5015860750 @default.
- W2010796656 creator A5043992437 @default.
- W2010796656 creator A5045930233 @default.
- W2010796656 creator A5072777093 @default.
- W2010796656 date "2014-11-01" @default.
- W2010796656 modified "2023-10-18" @default.
- W2010796656 title "Synergistic co-delivery of doxorubicin and paclitaxel by porous PLGA microspheres for pulmonary inhalation treatment" @default.
- W2010796656 cites W1693638809 @default.
- W2010796656 cites W1972651324 @default.
- W2010796656 cites W1975490265 @default.
- W2010796656 cites W1978283158 @default.
- W2010796656 cites W1980596533 @default.
- W2010796656 cites W1980803266 @default.
- W2010796656 cites W1980909702 @default.
- W2010796656 cites W1984601093 @default.
- W2010796656 cites W1988450779 @default.
- W2010796656 cites W1991766601 @default.
- W2010796656 cites W2043994894 @default.
- W2010796656 cites W2048620211 @default.
- W2010796656 cites W2049756302 @default.
- W2010796656 cites W2051160517 @default.
- W2010796656 cites W2055017037 @default.
- W2010796656 cites W2062181861 @default.
- W2010796656 cites W2067032133 @default.
- W2010796656 cites W2077529759 @default.
- W2010796656 cites W2077945404 @default.
- W2010796656 cites W2079126602 @default.
- W2010796656 cites W2079332722 @default.
- W2010796656 cites W2080638211 @default.
- W2010796656 cites W2090892185 @default.
- W2010796656 cites W2096439168 @default.
- W2010796656 cites W2101703583 @default.
- W2010796656 cites W2102440762 @default.
- W2010796656 cites W2103562758 @default.
- W2010796656 cites W2105395122 @default.
- W2010796656 cites W2106787323 @default.
- W2010796656 cites W2107552147 @default.
- W2010796656 cites W2153409108 @default.
- W2010796656 cites W2160547085 @default.
- W2010796656 cites W2168101221 @default.
- W2010796656 cites W2170529518 @default.
- W2010796656 cites W2270295692 @default.
- W2010796656 cites W2332884175 @default.
- W2010796656 cites W34291945 @default.
- W2010796656 doi "https://doi.org/10.1016/j.ejpb.2014.09.012" @default.
- W2010796656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25305583" @default.
- W2010796656 hasPublicationYear "2014" @default.
- W2010796656 type Work @default.
- W2010796656 sameAs 2010796656 @default.
- W2010796656 citedByCount "93" @default.
- W2010796656 countsByYear W20107966562015 @default.
- W2010796656 countsByYear W20107966562016 @default.
- W2010796656 countsByYear W20107966562017 @default.
- W2010796656 countsByYear W20107966562018 @default.
- W2010796656 countsByYear W20107966562019 @default.
- W2010796656 countsByYear W20107966562020 @default.
- W2010796656 countsByYear W20107966562021 @default.
- W2010796656 countsByYear W20107966562022 @default.
- W2010796656 countsByYear W20107966562023 @default.
- W2010796656 crossrefType "journal-article" @default.
- W2010796656 hasAuthorship W2010796656A5000852341 @default.
- W2010796656 hasAuthorship W2010796656A5005035675 @default.
- W2010796656 hasAuthorship W2010796656A5005243346 @default.
- W2010796656 hasAuthorship W2010796656A5015423597 @default.
- W2010796656 hasAuthorship W2010796656A5015860750 @default.
- W2010796656 hasAuthorship W2010796656A5043992437 @default.
- W2010796656 hasAuthorship W2010796656A5045930233 @default.
- W2010796656 hasAuthorship W2010796656A5072777093 @default.
- W2010796656 hasConcept C127413603 @default.
- W2010796656 hasConcept C141071460 @default.
- W2010796656 hasConcept C150903083 @default.
- W2010796656 hasConcept C170493617 @default.
- W2010796656 hasConcept C178790620 @default.
- W2010796656 hasConcept C185592680 @default.
- W2010796656 hasConcept C189942447 @default.
- W2010796656 hasConcept C202751555 @default.
- W2010796656 hasConcept C207001950 @default.
- W2010796656 hasConcept C2776694085 @default.
- W2010796656 hasConcept C2776954882 @default.
- W2010796656 hasConcept C2777292972 @default.
- W2010796656 hasConcept C2777383412 @default.
- W2010796656 hasConcept C2779820397 @default.
- W2010796656 hasConcept C2780165375 @default.
- W2010796656 hasConcept C2781303535 @default.
- W2010796656 hasConcept C42219234 @default.
- W2010796656 hasConcept C42360764 @default.
- W2010796656 hasConcept C55493867 @default.
- W2010796656 hasConcept C71924100 @default.
- W2010796656 hasConcept C86803240 @default.
- W2010796656 hasConcept C98274493 @default.
- W2010796656 hasConceptScore W2010796656C127413603 @default.
- W2010796656 hasConceptScore W2010796656C141071460 @default.