Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010803274> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2010803274 endingPage "946" @default.
- W2010803274 startingPage "941" @default.
- W2010803274 abstract "Timely diagnosis and prompt treatment can reduce the complications of scrub typhus. It is thus important to find easy laboratory tests to help in the diagnosis, especially in patients without eschar at initial presentation. Because serum aminotransferase elevation is common in scrub typhus, its associated factors and clinical implications need further investigations.We conducted a retrospective study in Kinmen, Taiwan, to collect clinically suspected scrub typhus patients notified to Taiwan Centers for Disease Control for confirmation during 2005-2010. Scrub typhus was diagnosed and Orientia tsutsugamushi was genotyped by serological or molecular assays. The laboratory data and clinical information were recorded for analysis.Overall, 344 suspected scrub typhus patients were reported to Taiwan Centers for Disease Control and 288 of them were certified scrub typhus. Scrub typhus patients had significantly more thrombocytopenia, serum aminotransferase elevation (76% vs. 54%, p = 0.001), higher frequency of fever, eschar, and lymphadenopathy, compared with nontyphus patients. Hepatic dysfunction in scrub typhus was associated with older age, longer fever duration, and absence of lymphadenopathy, but seemed to be unrelated to the rickettsial genotypes. Multivariate analysis showed that serum aminotransferase elevation (odds ratio: 3.75; p = 0.003; 95% confidence interval: 1.56-9.01) independently predicted scrub typhus. Furthermore, in suspected scrub typhus patients without eschar, 92% of true typhus patients had serum aminotransferase elevation compared with the nontyphus ones (odds ratio: 6.47; p = 0.028, 95% confidence interval: 1.23-34.11).Hepatic dysfunction in scrub typhus patients is associated with older age, longer fever duration, and absence of lymphadenopathy. Serum aminotransferase elevation can aid in the diagnosis of scrub typhus, especially in suspected patients without eschar." @default.
- W2010803274 created "2016-06-24" @default.
- W2010803274 creator A5005714550 @default.
- W2010803274 creator A5006213436 @default.
- W2010803274 creator A5026933700 @default.
- W2010803274 creator A5063550464 @default.
- W2010803274 creator A5069456338 @default.
- W2010803274 creator A5072593323 @default.
- W2010803274 creator A5079917695 @default.
- W2010803274 date "2016-12-01" @default.
- W2010803274 modified "2023-10-18" @default.
- W2010803274 title "Associated factors and clinical implications of serum aminotransferase elevation in scrub typhus" @default.
- W2010803274 cites W1498617252 @default.
- W2010803274 cites W1547559400 @default.
- W2010803274 cites W1911780358 @default.
- W2010803274 cites W1981591073 @default.
- W2010803274 cites W1992118361 @default.
- W2010803274 cites W2000677722 @default.
- W2010803274 cites W2009301521 @default.
- W2010803274 cites W2017925595 @default.
- W2010803274 cites W2054350958 @default.
- W2010803274 cites W2092061797 @default.
- W2010803274 cites W2110514337 @default.
- W2010803274 cites W2123680507 @default.
- W2010803274 cites W2124867669 @default.
- W2010803274 cites W2129150802 @default.
- W2010803274 cites W2142022289 @default.
- W2010803274 cites W2154832533 @default.
- W2010803274 doi "https://doi.org/10.1016/j.jmii.2014.10.005" @default.
- W2010803274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25556044" @default.
- W2010803274 hasPublicationYear "2016" @default.
- W2010803274 type Work @default.
- W2010803274 sameAs 2010803274 @default.
- W2010803274 citedByCount "5" @default.
- W2010803274 countsByYear W20108032742018 @default.
- W2010803274 countsByYear W20108032742019 @default.
- W2010803274 countsByYear W20108032742021 @default.
- W2010803274 countsByYear W20108032742023 @default.
- W2010803274 crossrefType "journal-article" @default.
- W2010803274 hasAuthorship W2010803274A5005714550 @default.
- W2010803274 hasAuthorship W2010803274A5006213436 @default.
- W2010803274 hasAuthorship W2010803274A5026933700 @default.
- W2010803274 hasAuthorship W2010803274A5063550464 @default.
- W2010803274 hasAuthorship W2010803274A5069456338 @default.
- W2010803274 hasAuthorship W2010803274A5072593323 @default.
- W2010803274 hasAuthorship W2010803274A5079917695 @default.
- W2010803274 hasBestOaLocation W20108032741 @default.
- W2010803274 hasConcept C126322002 @default.
- W2010803274 hasConcept C141071460 @default.
- W2010803274 hasConcept C142724271 @default.
- W2010803274 hasConcept C156957248 @default.
- W2010803274 hasConcept C203014093 @default.
- W2010803274 hasConcept C2779528086 @default.
- W2010803274 hasConcept C2780206043 @default.
- W2010803274 hasConcept C2780823208 @default.
- W2010803274 hasConcept C44249647 @default.
- W2010803274 hasConcept C71924100 @default.
- W2010803274 hasConcept C90924648 @default.
- W2010803274 hasConceptScore W2010803274C126322002 @default.
- W2010803274 hasConceptScore W2010803274C141071460 @default.
- W2010803274 hasConceptScore W2010803274C142724271 @default.
- W2010803274 hasConceptScore W2010803274C156957248 @default.
- W2010803274 hasConceptScore W2010803274C203014093 @default.
- W2010803274 hasConceptScore W2010803274C2779528086 @default.
- W2010803274 hasConceptScore W2010803274C2780206043 @default.
- W2010803274 hasConceptScore W2010803274C2780823208 @default.
- W2010803274 hasConceptScore W2010803274C44249647 @default.
- W2010803274 hasConceptScore W2010803274C71924100 @default.
- W2010803274 hasConceptScore W2010803274C90924648 @default.
- W2010803274 hasIssue "6" @default.
- W2010803274 hasLocation W20108032741 @default.
- W2010803274 hasLocation W20108032742 @default.
- W2010803274 hasOpenAccess W2010803274 @default.
- W2010803274 hasPrimaryLocation W20108032741 @default.
- W2010803274 hasRelatedWork W2018016861 @default.
- W2010803274 hasRelatedWork W2040866038 @default.
- W2010803274 hasRelatedWork W2152635638 @default.
- W2010803274 hasRelatedWork W2594076160 @default.
- W2010803274 hasRelatedWork W2901539352 @default.
- W2010803274 hasRelatedWork W3014161131 @default.
- W2010803274 hasRelatedWork W3086578845 @default.
- W2010803274 hasRelatedWork W3145116613 @default.
- W2010803274 hasRelatedWork W4376610219 @default.
- W2010803274 hasRelatedWork W4383336801 @default.
- W2010803274 hasVolume "49" @default.
- W2010803274 isParatext "false" @default.
- W2010803274 isRetracted "false" @default.
- W2010803274 magId "2010803274" @default.
- W2010803274 workType "article" @default.