FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010823141> ?p ?o ?g. }

• W2010823141 endingPage "131" @default.
• W2010823141 startingPage "121" @default.
• W2010823141 abstract "Single electrode whole cell current- and voltage-clamp techniques in conjunction with intra- and extracellular phoresis and extracellular application of pharmacological agents were applied to study neurons in deep layers of the brainstem of anesthetized, paralyzed and artificially ventilated cats. We compared slow rhythmic changes and stimulus-evoked postsynaptic current and voltage responses of neurons as they were recorded with fine-tipped microelectrodes filled with 2-3 M 'microelectrode solutions' or with 0.3 M 'patch solutions', or with patch electrodes. The experimental data were then compared with the effects of somatic and dendritic conductance changes simulated in a cell model. A new method was introduced for alternating current and voltage-clamp measurements performed at 300 Hz, which provided quasi-simultaneous measurements of slow changes of spontaneous synaptic currents and potentials. During current or voltage clamp, chemicals which affect voltage- and receptor-controlled conductances were ionophoresed intracellularly through single or theta-type glass electrodes. We show examples of activation of low-voltage activated Ca2+ responses after blockade of Na+ currents by intracellular QX 314 and K+ currents by intracellular Cs+ injections in addition to Sp-cAMPs to activate protein kinase A. TEA, NMDA and GABA were used to demonstrate the effectiveness of extracellular application of drugs through multibarrel electrodes or local application through a 'bath'. The various tests demonstrated that single electrode whole cell current- and voltage-clamp methods, in combination with various techniques for drug application, can be well applied to study the biophysical properties and pharmacological sensitivities of neurons embedded in in vivo networks within deep layers of the brain." @default.
• W2010823141 created "2016-06-24" @default.
• W2010823141 creator A5002943058 @default.
• W2010823141 creator A5030410265 @default.
• W2010823141 creator A5040700909 @default.
• W2010823141 creator A5066242185 @default.
• W2010823141 date "1996-08-01" @default.
• W2010823141 modified "2023-09-25" @default.
• W2010823141 title "Voltage-clamp analysis of neurons within deep layers of the brain" @default.
• W2010823141 cites W118589812 @default.
• W2010823141 cites W1533559637 @default.
• W2010823141 cites W1966354546 @default.
• W2010823141 cites W1973391232 @default.
• W2010823141 cites W1973691144 @default.
• W2010823141 cites W1973868940 @default.
• W2010823141 cites W1979323595 @default.
• W2010823141 cites W1980826539 @default.
• W2010823141 cites W1982662582 @default.
• W2010823141 cites W1983575543 @default.
• W2010823141 cites W1990463952 @default.
• W2010823141 cites W2009757016 @default.
• W2010823141 cites W2014068833 @default.
• W2010823141 cites W2015761713 @default.
• W2010823141 cites W2016234901 @default.
• W2010823141 cites W2017656839 @default.
• W2010823141 cites W2018189834 @default.
• W2010823141 cites W2020822973 @default.
• W2010823141 cites W2022504161 @default.
• W2010823141 cites W2029338036 @default.
• W2010823141 cites W2030034009 @default.
• W2010823141 cites W2035026316 @default.
• W2010823141 cites W2035248513 @default.
• W2010823141 cites W2041047250 @default.
• W2010823141 cites W2043242431 @default.
• W2010823141 cites W2051902737 @default.
• W2010823141 cites W2061756545 @default.
• W2010823141 cites W2062174464 @default.
• W2010823141 cites W2062857457 @default.
• W2010823141 cites W2064658959 @default.
• W2010823141 cites W2067240262 @default.
• W2010823141 cites W2068617048 @default.
• W2010823141 cites W2069076128 @default.
• W2010823141 cites W2069966134 @default.
• W2010823141 cites W2090186992 @default.
• W2010823141 cites W2094169507 @default.
• W2010823141 cites W2102632295 @default.
• W2010823141 cites W2346089158 @default.
• W2010823141 cites W991205576 @default.
• W2010823141 doi "https://doi.org/10.1016/0165-0270(96)00042-8" @default.
• W2010823141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8872877" @default.
• W2010823141 hasPublicationYear "1996" @default.
• W2010823141 type Work @default.
• W2010823141 sameAs 2010823141 @default.
• W2010823141 citedByCount "40" @default.
• W2010823141 countsByYear W20108231412012 @default.
• W2010823141 countsByYear W20108231412014 @default.
• W2010823141 countsByYear W20108231412015 @default.
• W2010823141 countsByYear W20108231412021 @default.
• W2010823141 countsByYear W20108231412022 @default.
• W2010823141 crossrefType "journal-article" @default.
• W2010823141 hasAuthorship W2010823141A5002943058 @default.
• W2010823141 hasAuthorship W2010823141A5030410265 @default.
• W2010823141 hasAuthorship W2010823141A5040700909 @default.
• W2010823141 hasAuthorship W2010823141A5066242185 @default.
• W2010823141 hasConcept C100837961 @default.
• W2010823141 hasConcept C111670793 @default.
• W2010823141 hasConcept C12554922 @default.
• W2010823141 hasConcept C147789679 @default.
• W2010823141 hasConcept C147944092 @default.
• W2010823141 hasConcept C169760540 @default.
• W2010823141 hasConcept C170493617 @default.
• W2010823141 hasConcept C17525397 @default.
• W2010823141 hasConcept C185263204 @default.
• W2010823141 hasConcept C185592680 @default.
• W2010823141 hasConcept C192562407 @default.
• W2010823141 hasConcept C195221683 @default.
• W2010823141 hasConcept C197341189 @default.
• W2010823141 hasConcept C2777151030 @default.
• W2010823141 hasConcept C28406088 @default.
• W2010823141 hasConcept C2910581834 @default.
• W2010823141 hasConcept C29694410 @default.
• W2010823141 hasConcept C55493867 @default.
• W2010823141 hasConcept C79879829 @default.
• W2010823141 hasConcept C86803240 @default.
• W2010823141 hasConceptScore W2010823141C100837961 @default.
• W2010823141 hasConceptScore W2010823141C111670793 @default.
• W2010823141 hasConceptScore W2010823141C12554922 @default.
• W2010823141 hasConceptScore W2010823141C147789679 @default.
• W2010823141 hasConceptScore W2010823141C147944092 @default.
• W2010823141 hasConceptScore W2010823141C169760540 @default.
• W2010823141 hasConceptScore W2010823141C170493617 @default.
• W2010823141 hasConceptScore W2010823141C17525397 @default.
• W2010823141 hasConceptScore W2010823141C185263204 @default.
• W2010823141 hasConceptScore W2010823141C185592680 @default.
• W2010823141 hasConceptScore W2010823141C192562407 @default.
• W2010823141 hasConceptScore W2010823141C195221683 @default.
• W2010823141 hasConceptScore W2010823141C197341189 @default.
• W2010823141 hasConceptScore W2010823141C2777151030 @default.

• next