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- W2010881851 abstract "Abstract We describe a simple, sensitive method for the determination of phenobarbital, diphenylhydantoin, carbamazepine, and primidone in whole blood by use of gas-liquid chromatography with temperature programming. The methylated derivatives of these anticonvulsants are well resolved. 5-( p -Methylphenyl)-5-phenylhydantoin was used as the internal standard. The proposed procedure requires only 100 μl of blood, which can be collected by finger stick. The lower limit of detection for each of the drugs is 0.5 mg/l. Analytical recoveries of drug from serum were excellent and standard curves were linear to twice the toxic concentration for serum." @default.
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- W2010881851 date "1976-09-01" @default.
- W2010881851 modified "2023-10-02" @default.
- W2010881851 title "Micromethod for the simultaneous analysis of phenobarbital, diphenylhydantoin, carbamazepine, and primidone in blood" @default.
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- W2010881851 doi "https://doi.org/10.1016/0026-265x(76)90007-2" @default.
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